Specialists in internal medicine from Davies Veterinary Specialists (Davies) in Hertfordshire and Willows Veterinary Centre and Referral Service in Solihull are urgently seeking canine patients with chronic small intestinal diarrhoea, to help with a multi-centre study on faecal matter transplantation (FMT).

Faecal matter transplantation (FMT) has been used in people to treat Clostridium difficile infections and has also been trialled in conditions such as irritable bowel syndrome, Crohn’s disease and ulcerative colitis.

The researchers believe that FMT offers a potential new option for the treatment of chronic diarrhoea in dogs and the study will investigate whether it contributes to a more rapid resolution of clinical signs. The study is being conducted in association with eight other private practices or universities around the country.

Julien Bazelle, a European Veterinary Specialist in Small Animal Internal Medicine at Davies said: "The goal is to recruit, over a short period of time, canine patients with chronic small intestinal diarrhoea, for a randomised trial in which the cohort receives or not FMT at the time of the initial investigations and prior to any other treatment.”

Dogs aged 6 months to 10 years with a history of chronic small intestinal diarrhoea (+/- other GI signs) are needed to participate in the study. Half of the dogs will receive FMT and the other half will be managed without. FMT will be performed in eligible patients during the sedation for their routine abdominal ultrasound. Transplanted faecal matter will be administered via a retention enema.

To be eligible, dogs must not have received antibiotics, probiotics or steroids recently.

If you have a potentially suitable patient please contact: julien.bazelle@vetspecialists.co.uk or Fergus.Allerton@willows.uk.net


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