In the past, few employers in the veterinary profession have chosen to advertise salary details, perhaps because they don't want to open a negotiation with their cards on the table, or perhaps they've been fearful of their existing employees finding out what they're prepared to offer a new candidate.
In the VetSurgeon forums, some employers have also remarked that the job isn't about money, and they wouldn't be interested in a candidate whose search criteria included the salary on offer.
The reality, of course, is that we all have bills to pay, children to feed or mortgages to cover and whilst few if any veterinary surgeons search for a job on the basis of salary alone, it's perfectly reasonable that the salary is part of their deliberations.
More than that, all the indications are that job advertisements which include salary details generate more, better qualified responses. Reed carried out a survey of 1000 jobseekers in 2016, 2/3rds of whom said they would be more likely to apply when a salary is displayed on the advert. Another company, Smart Recruit Online, found back in 2013 that job adverts which included a salary generated 30% more responses that those that didn't.
There are also indications that in the future, Google may start to prioritise jobs advertised with salary information in its search results.
To try and strike a balance between some employers' reluctance to display what they might be prepared to pay and the need for greater transparency, advertisers can now display a 'Minimum Offer' on VetSurgeon Jobs, described to the potential applicant as: "The minimum this employer is prepared to offer someone with the skills and experience needed to fulfil the job requirements. They may or may not be prepared to offer more. They may also be prepared to accept someone with a lower level of qualification or experience for an amount less than displayed."
Alternatively, employers can advertise a 'Pay Range', described to potential applicants as: "The employer expects to pay something within the displayed range, depending on their assessment of the value of the applicant's skills and experience to the practice."
In addition, employers can also display other benefits which are likely to be of more or less value to individual applicants, such as a RCVS fees, association subscriptions, health insurance and CPD allowances.
VetSurgeon.org Editor Arlo Guthrie said: "This is entirely optional, but I do hope as many employers as possible will make good use of this new feature, because all the research and anecdotal evidence suggests it’s what candidates want to hear, and it should lead to a better response. Not to mention how time-saving it is for two people to come to the table with realistic expectations."
AB Science, a young Paris-based biotech company, has announced the pan-European commercial launch of its veterinary anticancer drug, Masivet
Masivet was approved in November 2008 by the European Medicines Agency (EMEA) for the treatment of dogs with non-resectable grade 2 or 3 mast cell tumours. Masivet's active pharmaceutical ingredient is masitinib, a tyrosine kinase inhibitor. Masitinib, discovered and developed by AB Science, belongs to a therapeutic class of drug known as targeted therapy that is, according to AB Science, revolutionising the treatment of cancer in humans.
Alain Moussy, CEO of AB Science said: "Masivet is the first product ever registered as a cancer treatment in veterinary medicine. AB Science is a dynamic and very entrepreneurial biotech company, and is proud to have introduced a drug that can extend the life of dogs suffering from cancer ahead of the large pharmaceutical companies".
The company says Mastocytoma can be an aggressive cancer with a poor prognosis, and represents up to 20% of all cutaneous canine tumours. Some breeds are particularly susceptible, among them Golden Retrievers, Labradors and Boxers. Cancers have the same prevalence in dogs as in humans (1 dog in 4 will suffer from cancer during its lifetime) but surprisingly, no drugs developed for veterinary medicine with a demonstrated efficacy and safety have ever been approved until the arrival of Masivet.
The company claims two main benefits of the new treatment:
AB Science is a biotech company specialising in developing targeted drugs for high need indications, such as cancers, chronic inflammatory diseases and neurodegenerative disorders. Masitinib is the most advanced drug in the pipeline. Now being marketed in veterinary medicine, masitinib is also under development in humans, with phase 3 clinical studies in pancreatic cancer and in gastrointestinal stromal tumour (GIST).
Alain Moussy said: "This registration in veterinary medicine is good news for the future success of masitinib in humans, for whom we are aggressively developing it in cancers and other indications with high morbidity or pain.
"It is very unusual to develop such an innovative product simultaneously in veterinary and human medicines, and even more so that the product is registered in veterinary medicine first. There is no doubt that experts in human oncology will be watching Masivet's future very closely from now on.. However, people will have to wait a while before benefiting from masitinib because it is unlikely to be available to man before 2012".
For more information, see www.masivet.com and www.ab-science.com
Virbac has has announced the launch of Buprevet, a buprenorphine-based, injectable solution indicated for the potentiation of sedative effects of centrally-acting agents in dogs and for use in cats and dogs as part of a multimodal approach to analgesia.
Buprevet is presented in a 10 ml multi-dose bottle which can be broached up to 25 times and can be open for up to 28 days.
Sarah Walker MRCVS, Product Manager, said: "Buprenorphine is a potent, high affinity, synthetic opioid agonist which forms a key element of practice anaesthetic protocols and complements our existing anaesthetic range. Its potentiation effects means less sedation is needed in the pre-medication and in the anaesthesia, facilitating smoother recoveries with more comfortable patients."
"Buprenorphine is a tried and trusted solution for analgesia in many practices. Buprevet can be given pre-operatively to allow analgesia during and after surgery. It works effectively as part of a pre-emptive approach to analgesia, alongside products such as Inflacam and Carprox in our NSAIDs range."
Dechra Veterinary Products has launched TAF Spray (thiamphenicol), a next generation antibiotic wound spray for superficial wound infections in horses, cattle, goats, sheep and pigs.
Dechra says TAF Spray can also be used to treat infections of the claw and hoof in cattle, goats and sheep such as foot rot, interdigital dermatitis and digital dermatitis.
TAF Spray is the only licensed wound spray for horses and has a zero day meat withdrawal period for horses, cattle, goats, sheep, and 14 days for pigs.
Dechra is also highlighting the fact that TAF Spray is the only golden yellow coloured product of its kind on the market, allowing treatment areas to be distinguished clearly.
Brand Manager Emma Jennings said: “Dechra has developed TAF Spray in direct response to the research we conducted among farmers".
The research1 showed that 51% of the veterinary surgeons had used an antibiotic spray for the treatment of digital dermatitis – an infection that 92% of farmers had experienced in their livestock in the past 12 months.
Emma added: "Thiamphenicol is a highly effective antibiotic. With the brightly coloured spray format making it distinguishable from other treatments and a can that is able to be used in upright and inverted positions, we are sure that TAF Spray will become a popular product among veterinary professionals.”
TAF Spray comes in a 150ml can with a 360-degree nozzle which allows wounds to be targeted at any angle.
For further information about Dechra’s antibiotic portfolio, visit www.dechra.co.uk
Reference
According to the company, two promotional videos it prepared for social media have already reached more than 1.7 million people in the first two days of the campaign.
Virbac says that some of the UK's best loved pet influencers will also be promoting the campaign to their followers over the coming week.
What is a pet influencer, anyway? Someone who influences pets? I picture a Barbara-Woodhouse sort of character surrounded by a rapt audience of dogs: "Come on now, dogs, eat Veterinary HPM, it really is properly yummy, and sooo good for you."
I digress.
As part of the campaign pet owners will be able use an online protein calculator to check whether their current pet food is providing optimal levels of protein to their pet.
Pet owners will also be able to locate their nearest veterinary practice stockist using a new locator tool on the Virbac website and benefit from a discount voucher for their first Veterinary HPM purchase, which can only be redeemed in participating veterinary practices.
Tracey West, Nutrition Manager at Virbac, said: "Nutrition plays such a key role in the long-term health and well-being of our pets, and veterinary practices play such a key role in educating pet owners on this important subject.
"We’re delighted that as part of our ‘pro-veterinary’ strategy for Veterinary HPM, we will be able to help drive pet owners back into veterinary practices with this campaign."
For more information, speak to your Virbac Territory Manager.
Metacam 40 mg/ml solution for injection for cattle and horses contains 40 mg/ml of meloxicam, and is available in either 50 ml or 100 ml presentations. It is approved for subcutaneous or intravenous use in cattle, and intravenous use in horses.
Boehringer says the introduction comes on the back of a recent large-scale landmark study that found adding Metacam to standard antibiotic therapy for mastitis resulted in a greater first-service conception rate, fewer inseminations required to conceive and a higher probability of pregnancy by 120 days post-calving when compared to cows receiving antibiotic therapy alone1.
Boehringer Ingelheim’s technical manager Kath Aplin said: "By reducing the pain and inflammation caused by mastitis and other conditions, the use of Metacam 40 can result in improvements in cattle health and welfare, and may help limit any reduction in feed intakes. This is central to efficient herd management and productivity."
The company adds that new Metacam 40 mg/ml formulation offers a lower volume dose compared to the existing 20 mg/ml presentation, giving vets more flexibility in their use of Metacam.
The company says Salmoporc has been used on German and Polish farms for over 15 years and has proved to be safe and effective in controlling salmonella.
The vaccine can be administered orally in piglets and via subcutaneous injection in sows.
Company vet Dr Rike Schmelz said: "Salmonella in pigs is growing threat and an important zoonotic disease. According to the 2018 European Food Safety Authority (EFSA) report, salmonellosis is the second most reported zoonosis in Europe with over 90,000 cases reported in humans.
"Salmonella typhimurium and monophasic Salmonella typhimurium represented 17 per cent of confirmed human cases in 2017 so constitutes a major risk to humans."
VetSurgeon.org understands the new vaccine is expected in the UK sometime after October, before which it can be obtained under a Special Import Certificate.
Alexander McKinstry and Andrew Rutherford were both charged with writing letters indicating that Rebecca Inman had undertaken an assessment when in fact they had done the assessments themselves, the former without Ms Inman's knowledge, the latter with.
The charges were that all three, who worked at the same practice group in North-West, had been dishonest, misleading and risked undermining procedures designed to promote animal welfare.
At the outset of the hearing, all three admitted the charges against them and the Committee found serious professional misconduct in the case of all admitted charges.
The Committee then considered the sanctions for all three of the respondents.
In the cases against Mr McKinstry and Mr Rutherford, the Committee considered that the conduct was premeditated, that they had an increased position of trust and responsibility as practice directors at the time of the misconduct and that it was a breach of trust for the farm clients.
Additionally, Mr McKinstry had put Dr Inman’s professional reputation in jeopardy by not informing her of his conduct.
In mitigation, the Committee considered that there was no harm or risk of harm to animals, the conduct was not done for personal financial gain, that both had been open and frank in their dealings with the RCVS and had shown insight into their behaviour, and their previous good character and unblemished careers.
Regarding Dr Inman, the aggravating factors were the abuse of her position of trust as a registered mobility scorer and the breach of trust with the farm clients.
In mitigation the Committee considered that it had been an isolated incident involving, from Dr Inman’s point of view, a single telephone call.
It also considered that there was no risk of harm, no personal financial gain, her open and frank admissions in dealings with the RCVS, demonstration of insight, previously unblemished record, and efforts to avoid repeats and remediate past misconduct.
Paul Morris, chairing the Committee and speaking on its behalf, said: “The Committee carefully weighed the demands of the public interest, as well as the previously stated mitigating and aggravating factors and all the particular circumstances before it.
"The Committee concluded that a period of suspension was sufficient and proportionate in this case to meet the need to maintain public confidence in the profession and uphold proper standards.
"It had a sufficient deterrent effect upon others in the profession and was sufficient to mark that the disgraceful conduct was unacceptable.
“The Committee considered all of the factors before it, and decided that given the personal mitigation in this case, as set out above, a period of one month was appropriate and proportionate in all the circumstances."
The full findings of the Disciplinary Committee regarding this case can be found at: www.rcvs.org.uk/disciplinary
Dechra says Finilac inhibits prolactin secretion by the pituitary gland and therefore inhibits all prolactin-dependent processes, meaning it can also suppress lactation in bitches and queens.
Finilac, which contains cabergoline (50 microgram/ml), is presented as a liquid which can be given orally or in food. It is available in 3 ml, 10 ml, 15 ml and 25 ml bottles with 1 ml and 2.5 ml syringes included in every pack to ensure accurate dosing.
The dosage is 0.1 ml/kg bodyweight once daily for four to six consecutive days, depending on the severity of the clinical condition. Maximum inhibition of prolactin secretion is achieved after four to eight hours.
Dechra Brand Manager Carol Morgan said: "A false pregnancy can be a distressing condition for an animal and its owner so Finilac offers a fresh approach for cases with more severe symptoms that require veterinary intervention.
"It is easy to administer either directly into the mouth or by mixing with food and it doesn’t need to be transported or stored in the refrigerator, making it ideal as an ‘at home’ treatment that can be administered by owners."
Purina carried out a survey earlier this year which revealed the different ways British cat owners manage sensitivity to cat allergens2. They included removing the cat when sensitivities to allergens act up (76%), restricting the cat to specific places in the home (75%), using special cat products on the cat such as dander removers or allergen sprays (64%), bathing the cat (56%) and taking the cat to a groomer (52%).
92% also use a high-quality vacuum cleaner, 66% put covers on their furniture and 26% clean their home and furniture daily to remove traces of cat hair.
Dr Ebenezer Satyaraj, PhD, immunologist for Nestlé Purina Research and lead investigator on the research that led to the development of Pro Plan LiveClear, said: “Many people think that cat hair or dander is the allergen, but it’s actually what’s on it – the major cat allergen called Fel d 1, a protein that cats produce naturally in their saliva.” 3,4
All cats produce Fel d 1, regardless of breed, age, hair length, sex or body weight, but at differing levels.4-6 When cats groom themselves, Fel d 1 gets on the hair and skin through the saliva and with shedding, it eventually gets into the home environment. Feld d 1 attaches itself to any surface it comes into contact with and remains in houses for over a year or more.
Purina says Pro Plan LiveClear contains a specific protein, sourced from eggs, which binds itself to the Fel d 1 and safely neutralises it in the cat’s mouth, thereby reducing the amount of active allergen shed in the environment 7,8.
In a study, feeding Pro Plan LiveClear was shown to reduce the allergens on cat hair and dander by an average of 47%, starting in the third week of daily feeding7.
There have been no studies as yet which have tested the effect of this allergen reduction on human symptoms, but Purina says anecdotal evidence from consumers who have tried the product has been positive thus far.
Amena Warner, Head of Clinical Services at Allergy UK said: "Amena Warner, Head of Clinical Services at Allergy UK said: "There are a number of ways in which cat owners try to manage their exposure to cat allergens and keep their symptoms at bay, including taking antihistamines, using inhalers for quick symptoms relief as sensitivity to cat allergens is often linked to allergy-related asthmas, regularly cleaning and hoovering, bathing and grooming the cat by non-allergic family members. And if these measures do not work, current medical advice is often to relinquish the pet to limit exposure to the allergens.
"Every cat is unique though, and so the level of Fel d 1 they produce varies, just as every person's sensitivity level to these allergens is different. That is why there is no ‘one size fits all’ way to manage exposure to cat allergens. Every little bit helps so a combination of management tools often works best to help reduce cat allergens in your home - the combination is unique to your lifestyle. We welcome the development of Pro Plan LiveClear, which when used as part of a cat allergen management regime, could be a meaningful extra tool for affected households.”
Purina says Pro Plan LiveClear is not intended to replace other cat allergen-reduction strategies but to add another measure that can help reduce the cat allergen burden in cat households.
Pro Plan LiveClear is available at Pets at Home retail stores and from the Purina online shop as a complete life-stage range with six products tailored for Kitten, Adult and Adult 7+.
References
Ms Evans was charged with causing or allowing a veterinary nurse colleague to order a prescription-only medicine from a practice supplier knowing that it was intended for human use, and made a false entry prescribing the medication on the clinical records of a cat belonging to her nurse colleague.
She was also charged with falsely recording details purporting to be the results of the blood tests on cat and then entering notes on the animal's clinical history which falsely indicated that there had been a meaningful result, and then indicating to the animal's owner that there had been a meaningful result, when in fact the tests had failed to produce any meaningful results.
The final charge was that her conduct in making the false entry for the prescription-only medication, and all elements of the second charge was dishonest and misleading.
Ms Evans admitted the first charge on the basis that she had allowed rather than caused the order to be made, all the other facts of this charge were admitted.
She admitted the second charge on the basis that she had failed to inform the cat’s owner of the test results, all the other facts of this charge were admitted.
She also admitted that elements of her conduct had been dishonest and misleading.
Having found the charges proven by Ms Evans’ admissions, the Committee considered whether her admitted actions and conduct amounted to serious professional misconduct.
Ms Evans, through her legal counsel, accepted that the admitted charges passed the threshold for serious professional misconduct, though that question still needed to be determined independently by the Committee.
The Committee found that Dr Evans’ conduct had breached several key parts of the Code of Professional Conduct and its supporting guidance, particularly around honesty and integrity.
It also found aggravating factors in this case, including the risk to human health by allowing the prescription-only medication to be ordered knowing it was for human use, the abuse of her professional position, the breach of client trust, the potential adverse impact on the welfare of the cat for whom she falsified the blood test records, and the potential adverse impact on the welfare of the cat for whom she had falsely recorded the prescription-only medicine.
The Committee found no mitigating factors relating to the facts.
Paul Morris, chairing the Committee and speaking on its behalf, said in relation to the first charge: “In the Committee’s view, this irresponsible approach to a prescription-only medicine risked human health, potentially compromised an animal’s welfare, since the clinical record suggested the cat had been given Fluconazole when it had not, constituted an abuse of the trust placed in her as a registered veterinary surgeon and was in breach of legal provisions designed to safeguard human health.
“Such behaviour falls far below the standard expected of a registered veterinary surgeon, undermines public confidence in the profession and would be considered deplorable by colleagues and the public alike.
"The Committee was thus satisfied that charge 1 on its own amounts to disgraceful conduct in a professional respect.”
He added: “Acting dishonestly runs contrary to one of the most fundamental principles of the profession.
"The public need to know that they can rely on the honesty and integrity of the people to whom they entrust the care and welfare of their animals.
“Further, Dr Evans’ conduct in both incidents had the potential to undermine public confidence in the profession of veterinary surgery and bring the profession into disrepute.
"In all the circumstances, the Committee was satisfied that Dr Evans’ behaviour as reflected in charge 2 fell far short of the standard expected of a veterinary surgeon and amounted to disgraceful conduct.
“Accordingly, the Committee found proved the allegation that Dr Evans was guilty of disgraceful conduct in a professional respect.”
Having found serious professional misconduct in relation to all charges, the Committee considered what the most appropriate and proportionate sanction would be for Ms Evans’ actions and conduct.
In doing so, it considered 137 positive references and testimonials from Dr Evans’ professional colleagues and clients, poor staff morale at the practice at the time as well as compelling, exceptional evidence relating to Dr Evans’s health at the time of the two incidents.
In mitigation, the Committee considered the fact that Dr Evans had no previous disciplinary history and had a hitherto unblemished career as a veterinary surgeon; her open and frank admissions; the circumstances of pressures at work exacerbated by Dr Evans’ desire to please everyone and not let anyone down; the fact that Dr Evans was feeling very isolated; the significant insight into her conduct and its impact; effective and targeted remediation to ensure there would be no likelihood of the conduct being repeated; genuine expressions or remorse and apology; support from her employers; and the very significant number of positive testimonials.
Summing up the Committee’s decision on sanction, Mr Morris said “In all the, somewhat exceptional, circumstances of this case, the Committee was satisfied that a reprimand and a warning not to behave in this way again, would provide adequate protection to animals, as it was satisfied Dr Evans was most unlikely to ever make such a flawed set of decisions again.
“The Committee was satisfied that Dr Evans does not represent a risk to animals going forward, indeed from the character evidence it is clear that she always puts the welfare of animals first.
"She has also shown, since this episode, that she can work under pressure and not resort to making bad decisions and thus the Committee considered the wider public interest would best be served in this case by a reprimand and a warning.
“Notwithstanding the serious nature of Dr Evans' conduct, the Committee was satisfied that a fully informed member of the public would not be shocked if Dr Evans were allowed to continue to practise.
“The decision of this Committee is, therefore, that Dr Evans be reprimanded and warned about her behaviour.
"Dr Evans should, however, be under no illusion of how serious it is to have a finding of disgraceful conduct in a professional respect made against her and she should not take lightly the decision of this Committee to reprimand and warn her.”
www.rcvs.org.uk/disciplinary
For the research, 326 recruited veterinary practices examined 812 cats and 662 dogs using a standardised flea inspection protocol in April and June 2018.
Fleas were collected, the species identified, and pooled flea samples from each host were analysed for the presence of pathogens using PCR and sequence analysis.
Overall, fleas were found on 28.1% of cats and 14.4% of dogs.
Unsurprisingly, over 90% of the fleas on both cats and dogs were our dear old friends, Ctenocephalides felis.
The PCR results found that at least 14% of the samples were positive for at least one pathogen, and 11.3% were positive for Bartonella spp (35 from cats, 4 from dogs), a pathogen which was identified as a risk to veterinary professionals and others with direct animal contact in a 2010 research paper2.
Entomologist Professor Richard Wall from the University of Bristol said: "Fleas are the most clinically important ectoparasites of dogs and cats worldwide.
"Rising levels of pet ownership, climate change and globalisation are increasing the importance of a detailed understanding of the endemicity and prevalence of flea-borne pathogens. This requires continued surveillance to detect change.
"The results have shown the high numbers of cats and dogs that still carry fleas and the relatively high prevalence of Bartonella spp found in the samples provided, which is of significant concern for the health of the pet, pet owner and veterinary practice staff."
Nicola Barclay, Senior Product Manager at MSD Animal Health said: "The Big Flea Project results demonstrate the ongoing need for pet owners to understand the importance of flea prevention, particularly with the implications of infestation for human and animal health.
"It’s particularly important at this time of the year as the weather is getting warmer and infestation is more likely to occur.
"Our national launch today has been designed to raise awareness amongst pet owners and encourage them to seek advice from the veterinary practice.
"Building awareness of the risks of fleas to practices and pet owners is also at the forefront of our ongoing campaign."
Kruuse has announced that it has become the exclusive UK and Ireland distributor for Pulse Veterinary Technologies LLC shockwave systems, including the Versatron, Versatron 4paws and Equitron.
Shockwave therapy, otherwise known as extracorporeal shock wave therapy (ESWT), uses a high-energy sound wave that rapidly increases pressure as it travels through tissue. It is a non-invasive modality used to stimulate healing particularly in ligament, tendon or boney structures.
Andrew Groom, Managing Director, Kruuse UK Ltd said: "This agreement widens the Kruuse equine and small animal capital equipment profile within the UK and Ireland; increasing the range of technologies available to the veterinary practitioner , whilst providing aftercare support of existing shockwave users".
Eric Goorno , Chief Executive Officer, Pulse Veterinary Technologies LLC said: "This exciting partnership will further enhance our presence within the veterinary industry and allow Kruuse UK to bring leading edge technology to its customers, building upon its strong relationships within veterinary practices".
ISFM points to an editorial published ten years ago in The Lancet (Hypertension: uncontrolled and conquering the world), which presented alarming facts about hypertension in people: the risk of becoming hypertensive during a lifetime exceeds 90% for people in developed countries, with over 1.5 billion adults expected to have hypertension by 2025. It also said: 'screening is not done systematically, and the diagnosis is often made at a late stage when target organ damage has already happened'.
The Society says there are broadly similar concerns in our feline companions. Hypertension is a well-recognised condition in older cats, yet probably remains significantly underdiagnosed. The consequences can be severe, with target organ damage typically affecting the eyes, heart, brain and kidneys. Some damage, such as blindness resulting from complete retinal detachment, is irreversible. Other damage, however, is more amenable to antihypertensive treatment, highlighting the importance of early diagnosis and intervention. However, this presents challenges, particularly as routine blood pressure monitoring is generally performed infrequently in cats. Furthermore, cats are notoriously susceptible to stress in the veterinary clinic, which can lead to 'white coat hypertension' and hamper interpretation of results.
The new ISFM consensus guidelines are published in its Journal of Feline Medicine and Surgery1. The recommendations are those of an expert panel of veterinary clinicians and academics gathered from the UK, Australia, New Zealand, Spain, France and the USA, and cover several key areas. They include: how often to monitor blood pressure for cats of different ages and health status; when antihypertensive therapy is justified based on different systolic blood pressure readings and evidence of target organ damage; and what an investigation of hypertensive cats should include.
Samantha Taylor, a specialist in feline medicine and one of the co-chairs of the guidelines panel, said: "Well-illustrated and easy to read, it is hoped that these guidelines will encourage more widespread monitoring of blood pressure in veterinary clinics to increase the early identification of this treatable condition, and prevent the severe clinical consequences of untreated hypertension."
Accompanying the guidelines, which are endorsed by the American Association of Feline Practitioners, are further resources to assist veterinarians with the diagnosis of hypertension. A blood pressure evaluation form can be downloaded from the supplementary material; in addition, a series of short videos produced by the ISFM on measuring blood pressure in cats is available in various languages at https://www.youtube.com/user/iCatCare/playlists.
Pfizer Animal Health has launched Zylexis for horses, the first and only immunomodulator licensed in the UK to reduce the clinical signs of equine respiratory disease associated with over-crowding and stress.
Zylexis contains inactivated parapox ovis virus (iPPOV), a super-antigen which Pfizer says boosts a horse's immune system to reduce the effects of infectious respiratory disease1,2 - bridging the gap between potential and performance.
According to the company, Zylexis acts by stimulating the horse's non-specific immune system, inducing antiviral interferons and interleukins and stimulating innate immune cells. In this way it bridges the gap until the horse's adaptive immune system can develop a pathogen-specific response.3-5
Pfizer highlights research which has shown a 40.3% reduction in the clinical signs and duration of respiratory disease in young horses under conditions of crowding and stress and a significant reduction of purulent nasal discharge when using Zylexis.6,7 No local or systemic adverse events were observed in a 999 dose study.8
Wendy Talbot, National Veterinary Manager at Pfizer, said: "Zylexis has been licensed in the States and in Germany for a number of years. We believe Zylexis plays a pivotal role in helping to minimise the severity of respiratory disease outbreaks in these countries, therefore helping to maintain performance potential. It's a very welcome addition to the medicine box of UK vets."
The administration of Zylexis is recommended as a course of three single dose intramuscular injections on days 0, 2 and 9. The first dose should be administered shortly before the over-crowding or stressful situation.
Furthermore, the research found that among female dogs that had problems giving birth, French bulldog bitches are then 2.4 times more likely to undergo invasive caesarean sections than crossbred dogs.
This compared to brachycephalic bitches in general, which the RVC researchers found are 1.54 times more likely to need a caesarean compared with their longer-nosed pure breed or crossbred counterparts.
As part of the research, academics studied 20,000 bitches that required emergency treatment at 50 Vets Now veterinary clinics between 2012 and 2014.
Their findings, published in two papers in The Veterinary Record, highlight the substantial risks that bitches and their puppies face during the birthing process.
According to the first paper1, 3.7% of female dogs suffer from dystocia. Alongside French bulldogs, other pure breeds such as Boston terriers, chihuahuas and pugs, are also particularly at risk of birthing problems. Compared to crossbred bitches, Boston terriers are 12.9 times more likely to face birthing issues, pugs 11.3 times more likely and chihuahuas 10.4 times more likely.
The second paper2, which is available open access, examines the effects of difficult births more closely. It found that on average, 25% of puppies and 1.7% of the bitches do not survive problem births. Apart from the risk of death, problem births also mean that many bitches have to undergo painful and invasive surgery, with 48.6% of problem births needing caesarean surgery.
Bulldogs (also known as British Bulldogs), border terriers and golden retrievers were the top three breeds at risk of caesarean section once they have difficulty giving birth. Bulldogs are 7.6 times more likely, border terriers are 4.9 times more likely and golden retrievers are 4.1 times more likely to need the procedure compared with crossbreeds.
RVC veterinary epidemiologist and VetCompass researcher Dr Dan O’Neill said: "This new research is another piece of evidence suggesting that mankind may have gone too far in modifying dog breed shapes towards extreme conformation that can interfere with basic biological functions. We all need to fall back in love with dog-shaped dogs and move away from the current fascination with extreme-shaped dogs."
O’Neill, DG., O’Sullivan, AM., Manson, EA., Church, DB., McGreevy, PD., Boag, AK., Brodbelt, DC.(2019) Canine dystocia in 50 UK first-opinion emergency care veterinary practices: clinical management and outcomes Veterinary Record Published Online First:04 February 2019. doi: 10.1136/vr.104944.
The study1, which was conducted by surgery resident Dr Charlie Brincin at Highcroft Veterinary Group (soon to be Bristol Vet Specialists) and orthopaedic surgeon Dr Matt Matiasovic at Manchester Vet Specialists, looked at the records of 825 dogs that had been treated surgically for unilateral MPL at 10 referral centres, and then had a planned follow-up visit, including radiographs.
The frequency of, and reasons for, changes in further recovery recommendations were investigated.
The findings demonstrated that if the dog made an uneventful2 recovery after surgery, was presented without owner concern, and if no abnormality was found on physical examination, then radiographic findings only led to a change in recommendation in 3% (13/432) of these dogs.
Researchers say that this reflects similar research on the influence of follow-up radiographs in human medicine, and those of previous veterinary studies on post-operative radiographs, following uncomplicated tibial plateau leveling osteotomy (TPLO). These particular studies3,4 showed radiography had an impact on post-operative management in just 2%-3.8% of cases.
As a result of the MPL and TPLO studies, Highcroft Veterinary Referrals and Manchester Veterinary Specialists will no longer systematically perform follow-up radiographs on their patients, unless justified clinically.
Charlie said: “Radiographs are not without additional costs or risks - including radiation exposure, sedation-associated risks and strain on veterinary staff.
"Radiographic intervention should be clinically justified and our study suggests that if the dog had an uneventful recovery and is presented without owner or clinician raised concern, then repeat radiographs might not be necessary.
"This study also highlights the value of a thorough owner history and clinical examination for clinical decision-making when re-examining dogs following this orthopaedic surgery.”
The MPL study also evaluated factors which significantly increased the risk of finding radiographic abnormalities at routine follow-up, and those which led to a change in post-operative recommendation.
Lameness, administration of analgesia at follow-up, and history of unplanned visits prior to routine re-examination were associated with increased odds of a change in postoperative plan (P < 0.001).
In the absence of owner and clinician concerns, the odds of having a change in convalescence plans were not different, whether or not isolated radiographic abnormalities were present (P = 0.641).
Lead author Professor Clare Rusbridge, Chief of Neurology at Fitzpartick Referrals, conducted the study because of a lack of clarity on the recognition and diagnosis of the clinical signs associated with CM as opposed to syringomyelia (SM).
CM is an abnormality in the skull, making it smaller, and impacting on the brain to alter the flow of cerebrospinal fluid; this results in pain and a collection of fluid pockets within the spinal cord. These fluid pockets are commonly known as SM and over time can cause irreversible damage to a dog’s spinal cord. However it is not clear whether signs of pain in affected dogs are due to CM or SM or both.
To try to rectify this, Clare studied the medical records of all the cavalier King Charles spaniels diagnosed with CM-associated clinical signs presenting to her at Fitzpatrick Referrals over a five year period. She documented the historical and examination findings and related them to the MRI findings, including presence and size of the SM.
She found common signs in all dogs were vocalisation, spinal pain (neck, middle or lower back), reduced activity, reduced stairs or jumping ability, aversion to being touched or groomed, altered emotional state (described as being more timid, anxious, withdrawn or aggressive) and sleep disturbance.
A tendency to rub or scratch at the head or ears was common but was more likely in dogs with small or no SM suggesting that this may be a sign of head discomfort associated with CM. Head and ear rubbing was not associated with the presence of material within the middle ear (a condition which is also common in this breed and often given the acronym PSOM).
The only signs that were specific to SM were phantom scratching, scoliosis (twisted spine) and weakness and these were only present when the SM was large (at least 4mm wide).
Clare says this study is important because it suggests that CM alone is a cause of pain in many dogs. The aim now is to use the information gained in this study to develop a questionnaire to determine risk of CM and monitor the response to clinical signs.
Photo: Charlie on a bad day
The study, titled ‘Physics of animal health: On the mechanobiology of hoof growth and form’, represents the fruit of a collaboration between researchers in equine medicine, maths, physics and stem cell biology. It was conducted by the School of Veterinary Medicine and Science at University of Nottingham in collaboration with the Waltham Centre for Pet Nutrition and the Royal Veterinary College.
Lead author Dr Cyril Rauch said: "With new scientific inputs from physics, mathematics and biology, this study provides an entirely new paradigm regarding hard growing tissues such as the horse hoof, which can be applied across cattle, sheep and other species, to unify a set of apparently disparate conditions and clarify the roles of physics and/or biology."
Using hooves from horses euthanased for non-research purposes, the study revealed how it is possible for the hoof growth rate to be greater than the potential proliferation rate of epithelial cells. It also explained how the synthesis of the hoof capsule starts from the coronet and that the soft papillae undergo gradual transition through three interpapillary regions into hard keratinised tissue.
Mathematics, physics and cell biology were then used in the study to explain and describe how the dorsal hoof wall can grow in a curved manner rather than the usual straight manner as a result of faster growth from the coronary band at the quarters compared to the toe region.
Evaluation of the feet from live underweight and obese subjects (assessed using Body Condition Scoring) allowed the influence of body weight on the balances of the stresses affecting hoof growth to be evaluated. The results suggest that being proportionally heavier may promote straighter hoof growth and that being too lean may precipitate poor hoof growth and the development of a hoof with a dorsal curved shape.
The study also showed that a high concentration of insulin stimulated equine progenitor keratinocytes (the outermost layer of cells on the hoof wall) to grow in culture. If this also happens chronically within the live animal, it is possible that it could affect the growth stresses within the hoof and so promote a dorsal curved hoof shape.
Co-author Nicola Menzies-Gow said: "These results taken together can explain how the hoof grows and how it is possible for it to develop a dorsal curvature. However, it should be acknowledged that this does not take into account the genetic or metabolic influences on hoof growth nor the role of hoof trimming and shoeing in maintaining a mechanically healthy hoof. It is appreciated that the underlying biology of hoof growth remains an essential factor for hoof pathologies."
Dr Cyril Rauch continued: “Given that the hoof is a weight bearing element it is essential to untangle the biology from the physics in this system; only then can meaningful biological and/or physical causes be prescribed for particular hoof shape. Removing the cause(s) when physically or biologically possible is essential to resolve hoof conditions."
Zenalpha provides restraint, sedation and analgesia during non-invasive, non-painful or mildly painful procedures and examinations intended to last no more than 30 minutes2.
It is administered intramuscularly and takes effect within 5-15 minutes1, 2.
Dechra says patients also recover more rapidly2, potentially avoiding hospitalisation and allowing them to get home sooner.
Zenalpha contains the active ingredients 0.5 mg/ml medetomidine hydrochloride and 10mg/ml vatinoxan hydrochloride.
Medetomidine is an alpha-2 agonist used for its sedative and analgesic properties.
Vatinoxan is a peripherally selective alpha-2 antagonist which Dechra says has limited penetration across the blood-brain barrier, so it works to antagonise only the alpha-2 receptors located in the periphery, reducing cardiovascular side effects without impacting the quality of sedation or analgesia.
In a study of 223 dogs1 comparing a traditional alpha-2 agonist with Zenalpha, Zenalpha was found to minimise cardiovascular side effects while preserving reliable sedation and analgesia.
Claire Westoby, brand manager at Dechra said: ‘The next generation of alpha-2 agonists have evolved to provide the same effective and reliable sedation and analgesia, but with reduced cardiovascular side effects and a reduced chance of vomiting.
"This improves the sedation experience for the canine patient, as well as reducing the associated stress commonly experienced by veterinary teams and dog owners.”
Matt Gurney FRCVS, an RCVS and EBVS European Specialist in Veterinary Anaesthesia and hospital director at Anderson Moores, said: “It is really exciting to see the launch of an innovative new product, especially one with a unique mechanism of action that will improve the sedation experience for the vet team and our patients.
"Zenalpha not only provides a solution to cases where IV placement is not possible and a rapid onset IM option is required, but it also offers a rapid and complete recovery which ensures that dogs can be reunited with their owners and return home as soon as possible.”
Zenalpha is presented in a 10 ml glass vial in individually packed cardboard boxes.
For more information: www.dechra.co.uk/zenalpha or contact your local Dechra territory manager.
To watch Matt Gurney’s ‘Zennovation in sedation – the next generation of alpha-2 agonists’: www.dechra.co.uk/academy.
Leishmaniosis is caused by the parasite Leishmania infantum, which is endemic in some areas of Europe, but not in the UK. The patient in this case had not travelled outside the UK.
In endemic areas, the infection is carried by female sand-flies and spread through sand-fly bites. Transmission has also been reported via dog bites from an infected dog and infected blood transfusions, although the RVC says these routes have not been reported in the UK before.
Dogs with Leishmaniosis display a range of signs that can take months to years to develop after initial infection. Typical signs include:
Weight loss
Lack of energy or enthusiasm
Increased thirst and increased urination
Changes to the skin (particularly around the eyes, ears and feet)
Vomiting or diarrhoea
Lameness due to joint pain
Sudden nose bleeds
Soreness around the eyes
Treatment is available for dogs with leishmaniosis, but infection is difficult to clear and long-term medication is therefore frequently needed. Leishmaniosis can be zoonotic - meaning it can be passed to people in rare situations.
Apparently there is another leishmaniosis case reported in the Veterinary Record this week, this time where the dog was suspected of contracting the disease via sand-flies unintentionally brought back in its owners' luggage following a trip to Spain.
Myles McKenna said: "It is important to take note of this first reported case of likely dog-to-dog transmission of Leishmania infantum in the UK. Historically we had considered this to be a condition affecting dogs with a travel history to areas where Leishmania infantum is endemic. Dog-to-dog transmission in non-endemic areas has previously been reported, for example in the USA, but this case serves as a reminder to UK veterinary surgeons that we must be vigilant for conditions such as Leishmania in non-travelled dogs and that alternative transmission mechanisms do exist."
The Vet Record has published four recommendations to protect dogs and humans in the UK from leishmaniosis.
Photo: Bone marrow cytology showing macrophages with numerous intracellular organisms consistent with Leishmania species amastigotes. Credit Charalampos Attipa
Virbac Animal Health has announced that its medical castration implant Suprelorin 9.4mg has received a marketing authorisation for use in ferrets.
The neutering of male ferrets (hobs) is recommended to suppress fertility, decrease odour and reduce territorial aggressive behaviour and urinary marking¹. According to Virbac, Suprelorin offers temporary sterilisation but without the need for surgery, and its use prevents the high Luteinizing hormone (LH)/Follicle-stimulating hormone (FSH) levels which occur following surgery and which can play a role in the development of hyperadrenocorticism².
Suprelorin is a slow-release implant containing the gonadotropin-releasing hormone (GnRH) agonist deslorelin. Once injected under the skin of healthy, sexually mature and entire ferrets, the continuous low release of deslorelin from the implant causes an interruption of the HPA circuit, leading to a reduction in LH/ FSH levels and therefore testosterone production. This results in a reduction of libido, spermatogenesis and testicle size.
The implant lasts for up to four years, at which stage the ferret can be re-implanted to maintain the effect.
Chris Geddes MRCVS, Virbac Product Manager, said: "For owners looking for a surgery-free route to the castration of male ferrets and the problems it can cause, Suprelorin provides a simple and effective alternative."
Suprelorin 4.7mg has been available for use in dogs since 2008. Suprelorin 9.4mg was launched in 2011.
For further information, please contact your Territory Manager or call Head Office on 01359 243243.
References:
THE Society of Practising Veterinary Surgeons (SPVS) has published its annual Salary Survey, which provides a guide to what full time assistants are now earning.
The survey, which asked the society's members and anyone on the RCVS Register qualified for under three years to provide details about employees' salary levels, uniquely provides a breakdown of what full-time assistants are earning.
Respondents were asked to provide details of their basic salaries together with any benefits in kind such as rental accommodation, access to a car and CPD allowances, and total remuneration packages were calculated.
The survey, which is distributed along with the annual Fees Survey to SPVS members as a key benefit of membership, provides a breakdown of minimum, average and maximum salaries over categories ranging from location to the number of years qualified.
For the second year, student loan levels are featured, which, worryingly, highlights the increasing number of students graduating with large value loans.
Richard Hillman, SPVS President, said: "I very much welcome the publication of this important annual survey, which comes at a time when vet salaries and the fees we charge are under fire. It is interesting to note that the recent ‘league table' which effectively labeled us the ‘fat cats' among small businesses was based on the minority of corporate practices."
He added: "Our survey provides a very valuable base for employers to develop a transparent pay scheme and for employees to negotiate. It is particularly useful with new legislation on greater transparency of pay scales in businesses and the outlawing of salary ‘secrecy clauses' together with the Government's push for equality in male/female pay awards."
The SPVS annual Fees Survey, which provides a breakdown of fees charged across the small animal, cattle and equine sectors, will be published in September.
SPVS is run by practitioners for practitioners and if you'd like further information on the courses and membership benefits that SPVS offers, please contact the secretariat on 01926 410454 or visit the web site at www.spvs.org.uk
Ms Mulvey faced a total of nine charges against her:
Ms Mulvey did not respond to the charges, was not present at the hearing and was not represented.
She told the College that she couldn't attend for health reasons, but did not then provide any medical evidence and did not apply for a remote hearing, which was offered.
She had appeared before the Disciplinary Committee twice previously, facing a number of similar charges.
In 2016/2017, Ms Mulvey admitted all charges she was faced with and was found guilty of disgraceful conduct in a professional respect.
The Committee then decided to postpone the sanction for a period of one year.
In 2019, Ms Mulvey appeared before the Committee for the resumed sanction hearing and faced further new charges relating to failures to provide clinical history, failing to communicate with clients, failing to respond to requests for information from the College concerning complaints made against her, continuing professional development and indemnity insurance.
Ms Mulvey admitted the new charges and that she was guilty of disgraceful conduct in a professional respect, for which she was struck off for six months.
Taking into account the fact that this was not Ms Mulvey’s first time before the Committee, as well as new accompanying evidence, the Committee considered the facts of each subsection of each charge individually.
The Committee found all charges proved, apart from one subsection of charge 1.
The Committee then went on to decide if Ms Mulvey was guilty of disgraceful conduct in a professional respect, noting that it was entitled to consider the facts on a cumulative basis.
In other words, whilst any one charge may not fall far below the relevant standard expected of a veterinary surgeon on a standalone basis, it may when considered in conjunction with other failings that have been found proved.
The Committee found a number of aggravating factors in the case, including actual injury to animals (including death and amputation), dishonesty, breach of trust, sustained behaviour, disregard of the role of the RCVS, lack of insight by the defendant and previous adverse findings.
There were no mitigating factors.
The Committee then went on to decide upon a sanction.
Paul Morris, chairing the Committee and speaking on its behalf, said: “The Committee found that Dr Mulvey has demonstrated a wilful disregard for the role of her regulator and the systems that regulate the profession which are designed to ensure animal welfare.
"She has failed to learn from, or respond to in any meaningful way, her previous appearances before her regulator and advice given.
"The instant charges found proved dated back to shortly after the earlier suspension had elapsed.
"The Committee further noted that, if a period of suspension were to be imposed, at the end of the suspension Dr Mulvey would be entitled to resume practice without any preconditions.
“This is a case involving serious malpractice.
"It was sustained over a period of time.
"It followed previous adverse findings for almost identical failures.
"From as long ago as 2013, Dr Mulvey was given ample opportunity and support to remedy the deficiencies in her practice, which she squandered.
"Dr Mulvey’s conduct had very serious consequences for animal welfare.
"She continued, and continues, to display a wilful disregard for her responsibilities as a veterinary surgeon under the Code of Professional Conduct.
"Dr Mulvey’s conduct was a gross departure from the conduct expected of a veterinary surgeon.
“Dr Mulvey’s disgraceful conduct is so serious that removal from the Register is the only means of protecting animals and the wider public interest which includes protection of the public, the maintenance of public confidence in the profession, and the upholding of standards.”
Dr Mulvey has 28 days from being notified of her removal from the Register to lodge an appeal with the Privy Council.
https://www.rcvs.org.uk/concerns/disciplinary-hearings
Zoetis has launched UlcerGold (omeprazole) for the treatment - and prevention of recurrence - of gastric ulcers in horses and foals, presented in a syringe suitable for foals from four weeks of age and horses from 70 to 700kg.
Equine Gastric Ulceration Syndrome (EGUS) is a serious and common condition affecting horses and foals.2,3 Approximately 90% of racehorses, 60% of performance horses, 37% of leisure horses and 50% of foals have been shown to be affected.2,4,5 The condition is associated with injury to the mucosa of the oesophagus, stomach and duodenum, with prolonged exposure to gastric acid thought to be the primary cause.2,3 Risk factors include stress, intense exercise, a high-grain diet, intermittent feeding and illness.2,3 EGUS can have a profound impact on a horse's condition and performance and can ultimately be life threatening, especially in foals.3,5 It is a challenging condition to diagnose as the clinical signs are often vague and not always present.3 Gastroscopy is the only method currently available for a definitive diagnosis and treatment is usually based on acid suppressive therapy to allow ulcer healing.2
UlcerGold is indicated to treat and prevent the recurrence of gastric ulcers in horses, administered once-daily for 28 consecutive days at the full dose of 4mg/kg bodyweight followed by the reduced dose of 1mg/kg bodyweight for a further 28 days.1 It contains omeprazole, a proton pump inhibitor that suppresses gastric acid secretion.1,2 One syringe contains enough UlcerGold for a horse weighing up to 700kg. It can be used for foals as young as four weeks of age that weigh over 70kg and for breeding stallions.
Zoetis says UlcerGold is supported by a comprehensive gastroscope training programme, pricing model, client support and communications plan to ensure that it is a strong asset to veterinary businesses.
Penny McCann, Equine Product Manager, Zoetis UK Ltd, said: "UlcerGold is an exciting addition to our equine POM-V portfolio. We have designed a training, education and business programme to help practices make sure they get the best from our new product, not only in terms of gastric ulceration treatment but also practice health."