Merial Animal Health has announced that Zactran is now indicated for use in treatment of Swine Respiratory Disease (SRD) associated with Actinobacillus pleuropneumoniae, Haemophilus parasuis and Pasteurella multocida.

SRD remains a significant problem for the swine industry¹. Associated production losses include 30-70% morbidity, a mortality rate of 4-6% (and even higher in severely affected units), decreased feed efficiency and reduced growth rates².

Zactran contains gamithromycin. Merial says this bactericidal azalide rapidly accumulates in target lung tissue in less than 30 minutes, where it reaches and exceeds the MBC* for SRD pathogens for an extended period, helping to relieve clinical signs and minimise lung damage.

Zactran has a dose rate of 1ml per 25kg in pigs, administered by intramuscular injection.

The product is available in three pack sizes: 50ml glass bottle and 100ml and 250ml polypropylene shock-resistant bottles, and has a 3 year shelf-life.

References

1. VanAlstine W. (2012). Chapter 21 Respiratory System. In: Diseases of Swine. 10th Edition p. 348. Wiley Blackwell.
2. 2) Opriessnig T. et al. (2011). Polymicrobial respiratory diseases in pigs. Animal Health Research Review 12 (2); 133-148.

*MBC: Minimum Bactericidal Concentrations. MBC is the lowest concentration of drug which reduces bacterial counts by 99.9% (CVMP/627/01)

PS: Whilst you're here, take a moment to see our latest job opportunities for vets.