Zoetis, formerly Pfizer Animal Health, has launched Flexi4, a nutritional supplement for horses containing a patented combination of natural plant extracts designed to help maintain joint flexibility and the management of joint pain.

Flexi4 contains a blend of four plant extracts, Curcumin, Yucca schidigera, Salix alba and Boswellia serrata, which the company says have been shown to have anti-inflammatory, anti-pyretic and analgesic properties as follows:

• Curcumin, an extract from the roots of the herb Curcuma longa, has been shown to down-regulate inflammatory pathways and inhibit the production of inflammatory cytokines.¹ It has also been shown to reduce the release of GAGs from the cartilage matrix.²
• Yucca schidigera is a botanical extract containing saponins that suppress the intestinal protozoa, which are thought to have a role in joint inflammation in some circumstances.³ The extract also contains antioxidant polyphenols, which inhibit the enzymes of the arachidonic acid cascade, thereby reducing the production of inflammatory mediators.⁴
• Salix alba is an extract of white willow bark containing salicin, polyphenols and flavonoids. These are reported to have a positive effect on chrondrocyte viability, differentiation and function⁵ as well as anti-inflammatory, anti-pyretic and analgesic properties.⁶
• Boswellia serrata is the botanical extract of gum resin. Its role is to inhibit the pro-inflammatory cytokines and mediators which initiate the inflammatory process⁷ and produce anti-inflammatory activity at sites of chronic inflammation.⁸

Mary King, Olympic three day eventing team silver medallist, said: "When performing at the highest level it's important that my horses' joints remain flexible and free of pain. Using Flexi4 has made them more resilient to aches and pains during intense training and I am confident when competing that my horses are feeling the benefit of this natural product, helping them to perform at their very best."

Flexi4 is an apple-flavoured gel that is fed as a once daily supplement. It doesn't contain any substances listed as prohibited by the FEI.* For more information, contact your Zoetis Account Manager, call 0845 300 8034 or email customersupportuk@zoetis.com.

References

1. Jurenka JS, AlternMed Rev. 2009 Jun.
2. Clutterbuck 2009.
   
3. Cheeke et al. Journal of Inflammation 2006.
   
4. Wenzig et al. Agric Food Chem. 2008.
   
5. Shakibaei 2012 Evidence-based Complementary and alternative Medicine volume 2012, article ID 509383.
6. Nahrstedt et al. Wien Med Wochenschr. 2007.
   
7. Gayathri et al. Int Immunopharmacol. 2007 Apr.
8. Siddiqui, Indian J Pharm Sci. 2011 May-Jun.

*FEI prohibited substance list, 2013

Ceva Animal Health has introduced Cevazuril, a toltrazuril-based oral solution for the control of diarrhoea in sucking pigs. Cevazuril is a one-dose treatment that comes in two pack sizes, both with dosing pumps, for convenient administration to large or small herds.

Ceva says newborn sucking piglets are especially sensitive to coccidiosis and infection may result in lost daily gain of almost 2kg in the first 28 days, due to diarrhoea. The control of coccidiosis using toltrazuril prevents damage to the intestinal mucosa caused by the developmental stages of Isospora suis, helping to preserve digestive function and maintain optimal growth rate.

Toltrazuril is absorbed very slowly in the intestine for longer-lasting action. It works on all intracellular developmental stages of coccidia and reduces oocyst production, even if administered after the appearance of the first oocysts in the faeces of the host.

According to the company, extensive trials showed that three day old piglets treated with toltazuril at 20mg/kg gained 801 grams at weaning and 1601 grams by the end of the post-weaning period compared to control pigs.

Cevazuril is available in a 250ml pack with a pump or a one litre pack with a multi-dose injector. It complements Ceva's swine portfolio which includes the antimicrobials Cevaxel, Coliscour, Florkem, Marbox, Spectam Scourhalt and Tiamvet.

For further product information contact Ceva Animal Health Ltd, 90 The Broadway, Chesham, Bucks, HP5 1EG, telephone 01494 781510 or visit the website at www.ceva.uk.com

The RCVS Disciplinary Committee has agreed to accept undertakings from a Dorset veterinary surgeon, Philippa Ann Rodale MBE, in which she requests that her name is removed from the RCVS Register of Veterinary Surgeons with effect from 31 July 2015, and undertakes never to apply to be restored to it.

The Committee met on Monday 17 August, resuming a hearing which had been adjourned on 20 July. The adjournment had been made to allow Ms Rodale time to submit formal responses to the charges against her and indicate whether she agreed with them. In the event, as outlined by a letter from her solicitors received by the College on 14 August, Ms Rodale declined to comment on the charges and did not admit to any of them.

Ms Rodale did not attend the hearing on 17 August, however, the Committee decided to continue in her absence, on the understanding that, as evidenced by her solicitors’ letter, she was fully aware of the hearing and had voluntarily waived her right to be presented and represented.

The original charges related to Ms Rodale’s standards of practice (in relation to issues such as biosecurity, hygiene, in-patient facilities, drug storage and the disposal of hazardous waste, among other things) and also to a test for Intradermal Comparative Tuberculin. The charges relating to her standards of practice did not have complainants, as the College raised the matters itself; with respect to the Tuberculin test charge, the Animal and Plant Health Agency, as the relevant body, raised no objection to the proposed course of accepting undertakings.

In accepting the undertakings, the Committee felt that a contested hearing that could take up to seven days and involve up to eight witnesses for the College and up to three for the Respondent would not be in the public interest. Furthermore, since the 20 July hearing, Ms Rodale had retired and closed her practice. The Committee also noted that there had been no previous disciplinary findings against her, in what was otherwise a long and unblemished career.

Ian Green, chairing the Committee and speaking on its behalf, said: “The Committee is satisfied that the undertakings offered by the Respondent protect the welfare of animals since the Respondent has now retired and is no longer in practice. It is also satisfied that the reputation of the profession is upheld since the undertakings offered go beyond any sanction which the Committee could impose at the conclusion of a contested hearing, were any of the Heads of Charge to be found proved. It considers that it would not be proportionate or in the public interest for there to be a lengthy contested hearing.”

A Royal College of Veterinary Surgeons audit panel is to visit UK veterinary schools to assess how Extra-Mural Studies (EMS) is being carried out, identify good practice and make recommendations for improvement. The exercise is part of a package of measures which aims to improve the way that EMS helps veterinary undergraduates to gain skills and knowledge in a practice environment.

RCVS Council agreed to the implementation of proposals made by a Working Party set up to review the whole EMS process in November 2009. While the EMS system was largely agreed to be valuable and working well, some areas were identified for improvement. Many of the recommendations centred on a better understanding amongst all parties involved - students, practices and vet schools - of the aims and objectives of EMS for the student, and improved communication about expectations and outcomes.

As a first step, the Education Policy and Specialisation Committee has put in place an audit of EMS at the veterinary schools. It has commissioned Dr Barry Johnson, who led the original Working Party, together with practitioners David Black, David Wadsworth and Dr Chris Chesney, to follow through individual cases, talking to the students, practitioners and clinical tutors and EMS co-ordinators at the vet schools, to build a picture of how administration, communication and follow-up is managed.

Barry said: "The objective of the audit is to identify areas of good practice that can be shared, and identify where improvements could be made - it will also promote dialogue between practices and the schools. The exercise will be repeated over the next couple of years to track changes."

The first audit took place at the Royal Veterinary College in February, as part of the full RCVS visitation of the undergraduate degree programme. The EMS audit panel will report its initial findings in June.

The full report and recommendations from the EMS Working Party can be viewed at www.rcvs.org.uk/EMS.

Horiba UK Ltd is to host In practice haematology - beyond the pale!, a free CPD webinar presented by Ronnie Barron from the University of Glasgow Veterinary School, on Thursday 28th October at 7:30pm.

Ronnie (pictured right) will look at quality control and artefacts of sample quality and review the effects of different pathologies. By examining analyser output, he'll demonstrate how abnormalities of cells and plasma may affect measured parameters and their indices.

Using images, photomicrographs and video links, he'll move onto explain the techniques and equipment needed to complement analytical automation in order to confirm results quality. 

Ronnie said: "“We now have more near patient testing in veterinary haematology than ever before. Quality is key to best practice and ultimately superior patient care. Sod’s Law states that ‘if something can go wrong, it will!’, so along the way to your generating a Complete Blood Count, it pays to be aware of some of the pitfalls that you may encounter.

“One should never underestimate the value of gross exam and simple methods that can be used to ensure sample quality and results accuracy. Seeing is believing after all!” 

There will also be an open Q&A session with Ronnie after the presentation, so attendees are invited to bring any questions on all things haematology.

To register for the webinar, visit: https://register.gotowebinar.com/register/2458623866746094093 

Kruuse UK has announced that it will be launching its new Android telemetric ECG system at BEVA 2011.

The original Televet 100 supports transmission of ECG data to a range of approx 100m (330ft), allowing recording and displaying of real time data only within a confined lunging or riding arena. By linking this system to a mobile network via 3G Android phone and a Windows 7 based tablet PC, the new Televet system overcomes this range limitation.

The new system requires the rider/horse to carry a 3G mobile phone which transmits data over the mobile internet, allowing the veterinary surgeon to display and record real time data on any PC/laptop with internet access or mobile internet connection. This also includes GPS information collected by the phone allowing the ECG, heart rate and velocity of the horse to be displayed in parallel.

The Android Telemetric ECG system is specifically targeted towards veterinary applications in the field of sports horses where extended range is particularly useful, such as endurance riding, three day eventing and racing.

Televet software can now also be integrated in Dicom infrastructures in practice for data capture and recording.

Sarah Stokes, Kruuse Equine Territory Manager said: "the flexibility and simplicity of the system along with immediate access to ECG data of patients will be an invaluable diagnostic tool for UK vets allowing vital support for patients and owners wherever they are."

Visitors to the Kruuse stand at BEVA 2011 will also have the chance to win an Acer ICONI W500 tablet worth £500.

The BSAVA has announced its award winners for 2021 and 2022.

And the winners are:

Laurent Garosi (The Bourgelat Award for outstanding international contributions to the field of small animal practice), Sarah Girling (The Simon Award for outstanding contributions in the field of veterinary surgery), Kit Sturgess (The Woodrow Award for contributions to the advancement of small animal medicine), Martin Hawes (The Amoroso Award for outstanding contributions to small animal studies), Daniella Dos Santos (The J.A. Wight Memorial Award for an outstanding contribution to the welfare of companion animals) and Claire Bessant (The Ray Butcher Award for an individual who has made a significant contribution to animal welfare in the community).

Other winners included: Marzia Stabile (The Melton Award for the first named author of the best original research article on small animal surgery published in the Journal of Small Animal Practice), Ross Bond (The PetSavers Veterinary Achievement Award for the first author of the most valuable full research paper published following a BSAVA PetSavers' grant) and Rosanne Jepson (The Blaine Award for outstanding contributions to the advancement of small animal veterinary medicine or surgery).

BSAVA Honorary Secretary, Krista Arnold said: “Congratulations to all those that are receiving an accolade.

“All the nominations were exceptional, making judging particularly difficult this year.”

Goddards, the Greater London-based 46-branch, 3 hospital veterinary group has announced the move of its HQ to a new premises in a former police station in Woodford Green, Essex.

Twenty staff from the practice, including senior managers, the accounts and IT teams and the ProActive Pets Wellness Club, are now based at the new premises.

PC Philip Goddard of Woodford Green said: "After 60 years working within our hospital in Wanstead, our support teams had outgrown the office space available. The move provides a greatly enhanced working environment for them and has also freed up space in the hospital that will be used to improve facilities for staff there, including a new lecture room for our Nursing College and Training Department."

The new address is: Claygate House, Manor Road, Woodford Green, Essex IG8 8BX. Telephone: 020 8506 0703.

Petplan has launched a new system through which veterinary staff at Appointed Representative (AR) practices can activate 4 weeks Immediate Veterinary Cover (IVC) for clients' puppies, kittens and rabbits at www.petplanvet.co.uk.

Petplan says the new system will greatly improve its service to the veterinary industry, enabling same day information transfer, reducing the amount of paperwork and admin for veterinary staff as well as ruling out the chances of paperwork getting lost or delayed in the post.

Simon Masding, Petplan Head of Sales and Partnerships said: "Petplan has the most established cover note scheme in the market and due to the strength of our brand and the products we offer is able to generate more insured clients for practices than any other provider. Our team of Account Executives visit practices across the UK on a daily basis which means we understand the pressures of day-to-day practice life. Our new online IVC service is just one of the innovative ways we try to make things easier for veterinary staff so they can focus on looking after clients and their pets."

For more information about becoming a Petplan AR practice, and Immediate Veterinary Cover, call Petplan's Vetline on 0800 316 8800.

Any practices that activate IVC online at petplanvet.co.uk  before 31^st July 2012 will be entered into a prize draw to win an iPad.

Viennese biotech company BlueSky Immunotherapies says it has used its viral vector platform delNS to treat sarcoids in horses successfully, paving the way for a new cancer therapy in humans.

BlueSky says that conventional treatment for equine sarcoids, which are induced by tumour antigens E6 and E7 of the bovine papillomavirus, have only limited effect and typically result in the recurrence of the tumours.

However, research published by the company in PLoSONE¹ showed that sarcoids treated with delNS/E6E7 were completely and permanently eliminated.

For the study, 29 horses were treated with different regimes involving direct injection into the tumours over three years. 

Visible and very significant regression of the sarcoids was achieved in 20 of the treated horses, and 100% regression of the sarcoids in 10 equine patients.

Thomas Muster, CEO of BlueSky Immunotherapies said: "The complete elimination of very aggressive and difficult-to-cure equine sarcoids is yet another important proof of the potential offered by our delNS platform."

In addition, the systemic delNS-mediated immune stimulation eliminated non-injected sarcoids and the papillomavirus that caused the sarcoids.

Thomas added: "We are therefore confident that we will also be able to successfully heal and/or eliminate the cervical tumours of the women enrolled in the clinical trials currently under way."

Reference

1. Jindra, C., Hainisch, E. K., Rümmele, A., Wolschek, M., Muster, T., & Brandt, S. (2021). Influenza virus vector iNS1 expressing bovine papillomavirus 1 (BPV1) antigens efficiently induces tumour regression in equine sarcoid patients. PloS one, 16(11), e0260155. https://doi.org/10.1371/journal.pone.0260155 

The Disciplinary Committee (DC) of the Royal College of Veterinary Surgeons last week issued a reprimand to a veterinary surgeon for reckless certification of an equine passport, having found her to have been "wholly indifferent" as to whether the horse had been vaccinated properly against equine influenza.

Eleri Wyn Jones graduated from the University of Liverpool and qualified as a veterinary surgeon in 2006, before joining The Veterinary Practice on Bala Road in Dolgellau, Gwynedd, where she was also an authorised Local Veterinary Inspector (LVI). The principal of that practice is Iwan Parry, who himself was the subject of a DC hearing involving false certification earlier this year, for which he received a one-month suspension from the Register.

The Committee heard how, in late 2007, as Ms Jones was leaving the practice to begin her rounds, she was asked by a non-veterinary colleague to certify in a horse passport that two vaccinations for equine influenza had been administered. The horse in question was being liveried by a regular client of the practice, to whom the practice regularly dispensed veterinary vaccines (although Ms Jones was unaware of this), but had been recently purchased by someone who was not a registered client.

In evidence, Ms Jones admitted the certification process took her only 30 seconds and that she did not obtain any further information about the certification, either from clinical or non-clinical colleagues; nor did she check any other documentation before signing the passport, but assumed the vaccinations had been administered by a veterinary colleague. The Committee had to decide whether Ms Jones had acted recklessly, and to do so, Ms Jones' Counsel suggested the Committee would need to be satisfied that she "did not care less" whether or not the vaccinations had been given by a veterinary surgeon before signing the passport.

In reaching its decision, the Committee took into account the fact Ms Jones, on her own evidence, was generally familiar with RCVS guidance on certification and, as an authorised Local Veterinary Inspector, had certification training. It stated: "Whilst we recognise that Ms Jones received little or no mentoring from Mr Parry, we are satisfied that she would have been aware of the importance of veterinary certification. She was also aware that Mr Parry had been suspended as an LVI, due to certification issues, which had affected her own authorisation."

In view of these facts, and that Ms Jones made no attempt to obtain verification from any other source despite knowing she had not performed the vaccinations herself, the Committee decided that Ms Jones had been "wholly indifferent" to proper vaccination procedures and was therefore guilty of disgraceful professional conduct for reckless certification.

In reaching its decision on sanction, the Committee wished to remind members that cases involving improper certification would ordinarily result in suspension or removal from the Register. "We strongly disapprove of the circumstances in which Ms Jones certified this horse.

Clients, and external bodies, are entitled to rely upon the integrity of the veterinary surgeon in not certifying that horses have been vaccinated unless they have carried out the vaccinations themselves or have obtained full and proper evidence that vaccination has been carried out by another veterinary surgeon," it said.

In mitigation, however, the Committee took into account Ms Jones' age and inexperience, her previously good record, her good character and the significant number of supporting references from colleagues and clients alike. It was also mindful that any sanction's main purpose was to protect animal welfare and maintain public confidence in the profession, rather than to punish.

Nigel Swayne, chairing the Committee, concluded: "This is not a case where undertakings for training or monitoring are required. This isolated incident was a fateful misjudgement on a single occasion. We consider that the sanction most proportionate to the nature and extent of the charge, the public interest and the interests of Ms Jones is a reprimand."

Vet Futures has published the results of a survey of the profession in which only half of veterinary surgeons who graduated within the last eight years say their career has matched their expectations.

The online survey gathered views from 892 veterinary students (via the Association of Veterinary Students) and 1,973 veterinary surgeons who had graduated within the last eight years, during May and June this year.

Although 37% of graduates reported that their working lives had met their expectations, and a further 13% said it had exceeded them, this left 50% partly or wholly unsatisfied. Furthermore, 10% said they were considering leaving the profession entirely.

The RCVS and the BVA say the results should be a “wakeup call” to the profession.

Vets who have been qualified for five years or more were least optimistic about the future, rating their opportunities for career progression less positively than more recent graduates. They were also least likely to feel that their degree had prepared them for their current work. Meanwhile, only 34% of students felt that their degree was preparing them ‘very well’ for the work they wanted to do.

73% of students intended to work in the UK, with most aspiring to work in small animal/exotic or mixed practice, although one in 10 was as yet undecided. Of the students, 45% said they wanted to become practice owners or partners. Clearly the reality is proving less enticing, because only 25% graduates shared the same aspiration. In addition, nearly double the number of graduates said they wanted to work outside clinical practice (18%), compared to students.

When looking for a job, the three factors that both graduates and students agreed would have the greatest influence on their choice of career were intellectual satisfaction, location and a supportive environment.

This last requirement chimes with the fact that among the most popular suggestions for improvement to the veterinary degree were compulsory modules on managing stress, personal development and work-life balance, alongside more teaching of business and finance skills, and extra-mural studies (EMS) placements in a wider range of settings, such as industry.

BVA President, John Blackwell, said: “The drop off in career satisfaction for vets during this crucial first eight years in practice is something we can’t afford to ignore. It points to frustration over career development opportunities and dissatisfaction with support available in practice. For the veterinary profession to remain sustainable, and an attractive career choice for the best and brightest, we need to address these issues with some urgency.”

RCVS President, Dr Bradley Viner, said: “We clearly need to address the disconnect between expectation and reality for many recent graduates. Reviewing the educational foundation of the profession is a thread that runs through many of the proposed actions that will be outlined in the Vet Futures report due this autumn. The teaching and assessment of non-clinical skills – both as part of the undergraduate curriculum and within postgraduate education – will be important, as will be the promotion of non-clinical career pathways.”

The survey also covered issues such as students’ aspirations in terms of the type (size, ownership, sector) of practice in which they would like to work, and graduates’ future career plans. It also considers attitudes from both groups with respect to new technology.

The full research report “Voices from the future of the profession,” can be read at www.vetfutures.org.uk/resources.