Hill’s Prescription Diet Canine r/d has been reformulated following new findings regarding the role of protein in weight loss and the development of new fibre technology.
According to Hill's, trials of the new formulation resulted in some impressive results, with individual overweight animals losing at least 22% of their body fat in 8 weeks while still maintaining muscle mass.
In addition, the company has developed a range of support measures to help raise awareness about obesity and encourage pet owners to come forward. There's a new website: http://www.%20hillsweightloss.co.uk/ containing tips on weight loss and e-mailed reminders about returning to the surgery for weight checks; a pet passport containing information on helping the pet live a longer and healthier life, an anatomy poster that describes the dangers of excess weight gain and a practice display materials kit. Libby Sheridan, Veterinary Affairs Manager at Hill’s, “It can be time consuming to put together a really good wall or table display. This kit offers the opportunity for use in its entirety, while also giving scope to add individual elements for those who want to customize the display further.”
Hill’s Prescription Diet Canine r/d will be available in 1.5Kg, 4Kg and 12Kg bags. The recipe of the current 350g can remains unchanged.
For more information call Hill’s Customer Service on 0800 282 438 or (ROI) 1-800 626002.
The Royal College of Veterinary Surgeons is stressing the need for employers to check the registration status of the veterinary surgeons and veterinary nurses they recruit.
This comes following several incidences where veterinary surgeons have been found to be either not registered or registered in the wrong category. For example, foreign nationals wishing to work in the UK must be registered as home-practising members, not overseas-practising members. The latter category is for those practising overseas who wish to retain their MRCVS status.
Furthermore, there have been some cases of veterinary surgeons registering as ‘non-practising' and going on to carry out veterinary nursing roles, in the absence of relevant qualifications or being listed/registered as a veterinary nurse. This may be happening in cases where overseas veterinary surgeons are struggling to find work in the UK, possibly due to language difficulties.
RCVS President Jill Nute said: "Vets and veterinary nurses have complementary roles within the practice team. If someone wishes to undertake a veterinary nursing role, they should be qualified and registered as such. Many skills are taught in the veterinary nursing training that are not included in the veterinary degree. Although some veterinary nursing tasks can be carried out by veterinary surgeons, they certainly must not be undertaken by those who are not on the RCVS Register of Veterinary Surgeons".
She added: "Ours is a self-regulated profession and it is important that employers play their part by ensuring that practice employees are appropriately qualified and registered".
The registration status of vets and veterinary nurses can be checked on RCVSonline at: www.rcvs.org.uk/checkregister or www.rcvs.org.uk/vnlist respectively.
YourVets, the network of privately owned small animal veterinary practices has opened a new clinic in Dagenham, Essex and is re-opening an expanded and improved practice in Wythall, Birmingham later this month.
YourVets already has five clinics operating throughout the West Midlands and Essex, with the philosophy of providing a friendly, caring and high-quality service at an affordable price.
YourVets says its Dagenham clinic is a new, purpose-built facility while the Wythall premises has been enlarged and improved to supersede the old Pet Vaccination Clinic. The Wythall clinic has also been re-branded under the YourVets name, to reflect that fact that its veterinary care has grown to encompass the full range of veterinary procedures, rather than just vaccinations.
The clinics are equipped with high-tech equipment and top-class facilities. They offer a walk in appointment service to provide clients with maximum convenience and flexibility and have easy access to YourVets' own affordable 24-hour emergency service. Owners can also register their pets and order prescriptions online, for added speed and efficiency.
Jonathan Stirling, Managing Director of the PVC/YourVets group, said: "At Dagenham and Wythall, as with all our clinics, visitors and staff will be able to benefit from outstanding facilities, including air conditioned buildings, easy parking and the very latest medical equipment in a relaxed, fun and welcoming atmosphere."
Faye Fraser, Practice Manager at the YourVets Coventry clinic, says: "I love my role at YourVets. It gives me immense satisfaction to know that so many pets and owners have access to our truly affordable prices and professional veterinary service. We all care deeply about the animals we treat, and my love for animals extends into my home life, too. I have two rescue cats Tarot and Sorrell, who both need lifelong medical care."
YourVets currently has clinics at Coventry and Nuneaton in the West Midlands and Rayleigh in Essex. YourVets Dagenham opened on 4th February 2012 and the new-look YourVets Wythall will launch on 12th February 2012, with a special open day.
For more information about YourVetsvisit http://www.yourvets.co.uk/.
The Vet Futures Action Plan included a series of 24 work-streams to be completed over five years (2016-2020), building on the six core themes of: animal health and welfare; veterinary professionals’ wider roles in society; the health and wellbeing of veterinary professionals; diverse and rewarding veterinary careers; sustainable businesses and user-focused services; and leadership.
Vet Futures reports that over the last twelve months, key activities have included:
VN Futures
The VN Futures project (Action X of Vet Futures) isolated six ambitions to achieve by 2020, with the shorter time-scale reflecting the faster rate of both turnover and training for veterinary nurses.
A number of development groups have been created, focusing on each of these ambitions and creating specific actions to ensure their completion. Of these:
RCVS President, Chris Tufnell said: "When we launched Vet Futures back in 2014, the scope of the project seemed daunting and some were sceptical of our ability to succeed. However, through a robust process of evidence-gathering, analysis, action planning and now taking action itself, we are starting to make an impact on some of those core areas that are so fundamental to the future of our profession, such as animal welfare, technology, veterinary skills and knowledge, and leadership.
"Our Action Plan set out a five-year timeframe and we have made some really excellent progress in year one. This will form the foundation of work yet to come – although it remains important to ensure we scan the horizon for new issues that will have an impact on the profession, navigating our way through challenges as they arise."
BVA President Gudrun Ravetz added: "The excitement was palpable at the Vet Futures Summit last year and it spurred us on to roll up our sleeves immediately to start working on the Action Plan, and so a lot has been achieved already.
"Many of the actions are interlinked and so BVA, RCVS and the VSC are working closely together to oversee their delivery, but we have been particularly pleased at the high level of engagement and enthusiasm from others. The success of Vet Futures will be in the profession coming together to bring about the changes we need for a sustainable future.”
MSD says Lawsonia intracellularis is found on many finishing farms throughout the UK, and can affect weight gains, feed conversion ratios (FCR) and lead to increased mortality.
The new vaccine means that if piglets are vaccinated at three weeks, they will be protected against the bacteria from seven weeks.
Rubén Del Pozo Sacristán, technical manager for pigs at MSD Animal Health, said "Lawsonia intracellularis is present on most UK farms and can hamper a farm’s true potential as it spreads rapidly in faeces and on people or rodents, but symptoms can be hard to identify, as they’re often similar to many other diseases.
"Acute forms are often noticeable with symptoms such as diarrhoea or an increase in mortality, but the subclinical form, which is most common, can be hard to identify. Diarrhoea is not always present and often indicators are an increase in FCR and a reduction in weight gain leading to variation in pig performance, but this is similar to many other health issues.
"Administering an intramuscular vaccination will ensure every animal receives the correct dose, compared to other administrative routes. Porcilis Lawsonia can help reduce the clinical signs, production losses and mortality caused by Ileitis."
For more information on Porcilis Lawsonia, refer to the SPC sheet.
201 practices took part in the survey between 25th February and 4th March 2021. The main findings were:
Lizzie Lockett, RCVS CEO, said: “Although this survey took place in the midst of the lockdown and before the schools re-opened, there were some positive results here around staffing and the financial situation for practices. Hopefully this will mean that, as the restrictions ease going from spring into summer, many practices and practice staff will be in a position to return to a near-normal level of service and business.
"There were, however, still a few areas of concern, some of which will hopefully be resolved by the forthcoming easing of restrictions, for example, the difficulty in obtaining independent witnesses for the destruction of controlled drugs, with some 34% of practices reporting difficulties, compared to 20% in December.
“Once again, I would like to thank all those practices who responded to this and previous surveys, and continue to provide invaluable evidence and feedback about the current state of veterinary practice.”
The full results of the survey can be downloaded at: www.rcvs.org.uk/publications
Ian, who qualified from Melbourne University in 2004 after completing a neuroscience degree at Edinburgh University, first joined Rowe as a general practitioner in 2007.
He said: “Personally this achievement is incredibly rewarding, but I also see it as an important step for veterinary neurology in the UK.
"It’s a fast-growing field with an increasing need for expert treatment and care so it’s exciting to see it recognised at this level.”
https://www.rowereferrals.co.uk
Underlying the strategic plan are what the College says are its four updated values of compassion, collaboration, clarity and courage.
The plan lays out four strategic ambitions, each focused on one of its stakeholder groups, each one under the banner of 'Stronger Together'.
Veterinary professionals: "The RCVS will help veterinary professionals meet high standards and champion accessible, team-based veterinary care, delivered in settings that support professional autonomy and leadership."
This includes reviewing the Code of Professional Conduct and supporting guidance, achieving new veterinary legislation and ensuring that educational standards and career pathways meet the diverse needs of society.
Animal owners and keepers: "The RCVS will support animal health and welfare and public health by enabling access to veterinary care informed by the needs of consumers and service users."
This includes supporting and informing the public in how to get the best from veterinary professionals, with increased transparency, agency and choice.
Society at large: "The RCVS will champion the role that veterinary professionals play in One Health and public health, take a leadership role on environmental sustainability and biodiversity, and continue to look at how it can play a role in the global veterinary professions."
This includes leading the conversation on issues such as the cost of veterinary care, building enthusiasm for veterinary work in the minds of the next generation of potential professionals and ensuring veterinary professionals responsible for public health are well supported with robust standards and safeguards.
Staff team and governance: "The RCVS will attract and retain the diversity of talent and skills to deliver what’s needed now and anticipate what might be next and build a culture that allows people to thrive."
This includes developing an infrastructure for success, including the new RCVS headquarters, and underpinning structures for finance, communications and digital, creating a working culture with sound values and supportive management.
Lizzie Lockett, RCVS Chief Executive Officer, said: “The overall theme of the plan recognises that there are many other individuals and organisations that have a stake in our mission to inspire confidence in veterinary care and protect the public interest by ensuring animal health and welfare, and public health, are advanced through thriving world-class veterinary professions.
“This is where the ‘stronger together’ comes in, recognising that, in our role as a royal college that regulates, we are very well placed to bring people and organisations together to meet our common purpose of improved animal health and welfare and public health in a collaborative, proactive way.”
www.rcvs.org.uk/strategy25
Ceva Animal Health has launched two iPhone Apps for veterinary professionals and cat owners.
The 'Metoclopramide' iPhone App calculates both the daily fluid requirements and the volume of metoclopramide to add to the fluid bag for a dehydrated, vomiting cat or dog.
The 'Cat Stress' App helps pet owners to measure the stress levels of cats by asking questions about their home environment; this will help evaluate the effect that modern living has on feline stress levels which may, in turn, encourage owners to take action to help prevent cats developing stress related behavioural or medical problems in later life.
The 'Metoclopramide' iPhone App is available to download from the iTunes store here.
The 'Cat Stress' iPhone Apps is available to download from the iTunes store by searching for 'Cat Stress'.
For further information, please contact your Ceva Animal Health representative or call the veterinary support team on 01494 781510.
Petplan has launched a new service to pay vet claims direct to practice bank accounts via BACS.
Petplan says it pays out nearly £3 million in claims each week, which is the equivalent of paying £35,000 per year to each veterinary practice in the UK. Paying practices by BACS means that the money is received faster and there is no administration required by the practice, freeing up more time for clinical work.
As part of this new service, practices also receive a detailed statement by email providing a breakdown of the client claims the payment relates to.
To register to receive claim payments by BACS, visit petplanvet.co.uk and complete an online form.
Simon Masding, Petplan's Head of Sales and Partnerships said: "Petplan has a great relationship with vet surgeries and we know in the last few years some practices have had increasing pressure on cash flow due to reduced footfall and rising costs. We are constantly looking for new, smarter ways of working to help our partners and wanted to get claim payments to vets even faster."
Petplan's Vet of the Year Brian Faulkner said: "Most people become vets because they love to work with animals, and the paperwork is merely a downside of the job. It's great to see that Petplan has reduced the time we have to dedicate to admin, meaning we can concentrate on the important things, like improving the health of Britain's pets."
For more information visit www.petplanvet.co.uk
The BVA says that securing 'Great Workplaces' will be a collaborative assessment process.
Each workplace will have a dedicated, experienced accreditor from a veterinary background, who will work with leadership teams and employees to gather a full picture of their workplace.
Workplaces will be assessed in four main areas: health and wellbeing, leadership and management, culture, and learning and development.
Successful workplaces will achieve either gold or silver accreditation.
Those that don’t meet the criteria yet will be recognised as ‘working towards’ accreditation and will be supported to make the changes needed to achieve success next time around.
Successful workplaces will hold their accreditation for three years and at the end of that period they will be required to undergo reassessment to retain their accredited status.
BVA President Anna Judson said: “As well as attracting more people to join our veterinary profession, ensuring we retain the incredible talent we already have is critical to building a resilient and sustainable veterinary workforce.
"Positive workplace culture is central to achieving this and Great Workplaces by BVA is an innovative new approach that puts the well-being of vet teams front and centre.
"The knock-on impact will be good for vets and vet practices, good for clients and ultimately, good for animal welfare.
Photo: BVA
“Workplaces accredited under this new scheme, will be seen as employers of choice, attracting top talent who seek fulfilling careers and a healthy work-life balance.
"For existing team members, working in a recognised Great Workplace could enhance job satisfaction.”
A number of workplaces have already undertaken Great Workplaces accreditation during a series of pilots in 2023.
Two, Westport Veterinary Clinic in Linlithgow and South Moors in Devon, have become the first veterinary workplaces to receive a silver accreditation.
Fiona Leathers at Westport Veterinary Clinic, said: "At Westport Veterinary Clinic, our collaboration with the British Veterinary Association and its Great Workplaces accreditation scheme has been transformative.
"It has given us invaluable insights into how this initiative positively impacts workplace culture and employee well-being.
“The simplicity of the accreditation process and the approachable nature of BVA’s accreditors facilitated seamless integration of the scheme’s principles into our daily routines.
"The tangible impact of the Great Workplaces accreditation has been profound.
"It's fostered a more inclusive, supportive, and cohesive environment, elevating employee satisfaction and bolstering team morale significantly.
"This experience extends beyond personal growth; it solidifies our belief in cultivating healthy work cultures.”
www.bva.co.uk/great-workplaces
Kruuse has announced that it has entered into an agreement with Henry Schein Inc., under which the American supplier of veterinary, dental and medical healthcare products and services will acquire a majority shareholding in the company.
Under the agreement - the financial details of which are not being disclosed - the Kruuse family will retain the remaining shareholding and work with Henry Schein to accelerate global expansion of the company.
Kruuse and Henry Schein have already been business partners in the marketing and distribution of animal healthcare products. Kruuse says it expects the deal to create significant growth prospects, particularly for its own products and brands which will in the future be included in Henry Schein's offering to its animal health customers.
Chairman of the Board of Kruuse, Peter Eriksen Jensen said: "We are very pleased with the agreement with Henry Schein, which fulfills our wish to find a strong investor to support our efforts of creating an attractive future for our company. We complement each other extremely well - and the partnership provides us with a much broader platform to market our products. In Henry Schein, we will get an ideal partner to realize our ambitious growth strategy."
Kruuse's CEO, Jesper Smith said: "It is very important to us, that we and our new owner have a mutual understanding of the values and customer-centric focus on quality and services which have guided us throughout Kruuse's 119 years' history. We will continue this approach under our new ownership, making sure that our employees, customers, and suppliers continue to experience all the benefits of Kruuse - now in an even stronger set-up and with new, exciting prospects for the future."
The Farm Vet Champions initiative has been set up to build a supportive community of farm animal veterinary professionals to collaborate in championing good antibiotic principles.
Led by RCVS Knowledge and funded by the VMD, the project has brought together a number of UK veterinary and agriculture organisations to develop free learning materials for farm veterinary professionals.
The new online course covers:
A course offers a total of 20 hours of free on-demand CPD.
The second phase of the initiative, due to start development over Summer 2021, will provide online and in-person networking opportunities for Farm Vet Champions to learn from one another by sharing their experiences and working together towards the common goal of good antibiotic stewardship.
Chris Gush, Executive Director of RCVS Knowledge, said, “With antimicrobial resistance being one of the top 10 health threats facing our planet, we are delighted with the quality of the Farm Vet Champions course and we look forward to connecting with farm vets across the UK to tackle AMR. Farm Vet Champions is just the beginning of our work in antimicrobial prescribing, and we look forward to building on our resources that will benefit all animals, the public and society.”
Fiona Lovatt, Farm Vet Champions Clinical Lead, said, “I am incredibly proud of the Farm Vet Champions project and extremely grateful to every member of our steering group who have been instrumental in the creation of high-quality and engaging learning materials. I encourage all UK farm vets to sign up and join us on the journey to tackle AMR.”
Farm Vet Champions can be accessed for free at https://learn.rcvsknowledge.org/
The Association says that the qualification is intended to give vets the chance to conduct clinical research relating to their work – in particular vets working in general practice.
The qualification, validated by Nottingham Trent University, is aimed at people who already have any accredited Postgraduate Certificate (60 credits at Level 7) relevant to some aspect of veterinary medicine or surgery.
The programme is based on a further 1,200 study hours and could be flexibly achieved in two years of part-time study or up to five years, depending on the project type and an individual’s availability.
Frances Barr, BSAVA Academic Director, has developed the most extensive CPD programme in the 60-year history of the organisation. She said: "It’s a really significant addition to the BSAVA CPD programme and another step supporting lifelong learning, which we hope will have a very positive impact on the profession."
"Anyone who has an interest in clinical research – such as evaluating risk factors for a particular disease or factors that might influence an outcome – will find this an ideal way to satisfy their enquiring mind.
"If they have the motivation to keep developing a deeper understanding, we can provide encouragement and support for how to answer those clinical questions."
The Masters programme starts with online study into the principles of clinical research, which students will then apply to their own research project.
Students will be allocated a ‘matched’ supervisor who will provide project advice and guidance, plus the BSAVA team will be on hand to ensure ongoing support and encouragement.
The programme starts in January 2017 and applications open this October.
Frances added: "It can sometimes be quite difficult to get going in research when you don’t know how to do it, so having taken the first step in a supported environment we hope many will go on to do extend their clinical research ambitions.
"BSAVA’s mission is to support vets at every stage of their careers. There are often limited opportunities for practitioners to conduct clinical research, so this is a qualification that enables vets to do just that."
For more information, please contact the BSAVA Education team at masters@bsava.com
There are three awards, two ruminant and one companion animal, of up to £4,000 each. Each project needs to be completed within 1-2 years and the veterinary practitioner proposals will be judged by university academics to ensure independent assessment.
Michelle Townley, Veterinary Advisor at MSD Animal Health (pictured right), herself a winner of an MSD bursary in 2001, said: "Our existing Research Bursaries are well-known amongst practitioners focusing on ruminants, having run for 6 years. For the first time, however, we are offering a broader level of support which includes both ruminant and companion animal practitioners. Our aim is to engage as many people as possible as we view our investment in research, and the pursuit of new knowledge, as the lifeblood of the veterinary industry."
The deadline for entries is 30th November 2017.
For further information, visit: www.msd-animal-health.co.uk/researchbursary.aspx.
The company says the new award, which invites nominations from both pet owners and practices, is also to help raise awareness of Pet Diabetes Month, which this year takes place in November.
Pet Diabetes Month will have an emphasis on detecting the condition through initially screening urine samples, with pet owners being encouraged to visit their local vet practice.
Caroline Darouj, Product Manager at MSD Animal Health said: "There will be two categories for the award – one for the Pet Diabetes Professional Carer of the Year and one for owners – the Pet Diabetes Carer of the Year.
"A diagnosis of diabetes and decision to treat a feline or canine patient requires a lifelong commitment from the owner. We want to recognise the many loving pet owners who commit to giving their pet regular insulin injections and the practice staff who support them. We also want to create awareness of the importance of early diagnosis so pet owners can more easily spot the signs and realise that treatment is an option, which can be made easier with the use of the VetPen."
She added: "In veterinary practices there are outstanding individuals who make an extra effort to provide reassurance for pet owners when they may feel overwhelmed or fearful of their ability to cope with their pet’s diabetes. The Professional Carer of the Year could be a vet, vet nurse, animal nursing assistant or receptionist."
Pet owners and practice staff can nominate in either category. All the details can be found at www.mypetonline.co.uk/petdiabetesmonth.
The website will also be a central source of information about what’s going on during the campaign, tips on diabetes detection and prevention, plus a number of activities to get the attention of pet owners of all ages.
The deadline for nominations is 30th November 2017.
For further information please contact your MSD account manager.
Originally launched in 2022, the company says the platform now has thousands of users including hundreds of imaging specialists from around the world.
Dr Oliver Gehrigsaid: "One of veheri's goals is to promote worldwide cooperation with experts as medical progress has always emerged from the collective, and the best in the field play a central role in this.
"We connect veterinarians globally via our global veterinary community, where cases can be uploaded and discussed.
"Veheri also offers direct access to one of the largest expert networks worldwide through our Diagnostics-Teleradiology Module”.
Teleradiology reports can be requested from €100 depending on the modality, and the company offers practice membership plans starting at €200 per month.
https://www.veheri.com
The 4D heart model, which can be viewed at: https://static.imascono.com/heartViewer, was designed in conjunction with Alejandro Suarez Bonnet, senior lecturer in comparative pathology at the RVC and consultant pathologist at The Francis Crick Institute.
The model demonstrates the structural changes in the mitral valve and associated heart chambers across stages A to D — from dogs at risk (stage A), through preclinical disease (stages B1 & B2), to symptomatic heart failure (stages C & D).
It has been designed to help pet owners understand the condition’s progression and support clearer communication of monitoring and treatment options.
Callum Watkins, brand manager at Dechra, said: “MMVD often catches dog owners unawares due to the silent early signs and the slow progressive nature of the condition.
“Our new 4D heart model will enable vets to clearly demonstrate the different stages of the disease, including the structural changes in the mitral valve and associated heart chambers, to aid discussions on the monitoring and treatment options.”
https://www.dechra.co.uk/companion-animal/internal-medicine/cardiovascular-disease.
BVA Congress 2008 will combine both political and CPD sessions under the theme ‘Vets in a changing environment’. Building on last year’s BVA Congress in Belfast, hailed by many delegates as ‘the best Congress for many years,’ Congress 2008 aims to provide excellent networking potential at a friendly, popular Congress where wide-ranging CPD and political sessions are all part of the attraction.
Alongside a thought-provoking and topical contentious issues programme will run three parallel wide-ranging CPD programmes run by partner organisations including the Association of Government Vets, Association for Veterinary Teaching & Research Work, British Cattle Veterinary Association, British Equine Veterinary Association, British Small Animal Veterinary Association (Metropolitan Region), British Veterinary Zoological Society, BVA Overseas Group, Laboratory Animals Veterinary Association, the Royal Veterinary College, Sheep Veterinary Society and the Society of Practising Veterinary Surgeons.
BVA says Congress 2008 has something to offer everyone, whether Defra’s new chief scientist Professor Bob Watson talking on climate change - the global challenge, Stephen Gates on inspirational leadership, Neil Morrison OBE on empowerment through livestock, Adrian Boswood on cardiovascular medicine or Keith Chandler on field equine dentistry.
This year’s Congress will be held in the heart of London, at the Royal College of Physicians by Regents Park, a venue which offers exceptional conference, meeting and banqueting facilities with convenient links to transport on its doorstep. Having returned to London, BVA Congress will also make use of some of the facilities the capital has to offer with the Party Night at the world famous Café Royal and the Congress Banquet at Stationers Hall, one of the few ancient livery halls remaining in the City of London and certainly one of the most beautiful.
Date and location: 25 - 27 September, Royal College of Physicians, London
A research project funded by equine charity The Horse Trust has succeeded in killing equine sarcoid cells in vitro by silencing a gene in the virus that causes sarcoids. The researchers are now hoping to obtain funding for clinical trials using the new technique, which could result in a more effective, non-toxic treatment for sarcoids.
Sarcoids are skin tumors caused by infection with the Bovine Papillomavirus (BPV). They are the most common type of tumour found in horses - the estimated prevalence in the UK is 6-7%. Although the disease is rarely life threatening, many horses with sarcoids are euthanased because the condition is untreatable or because the horse is unsellable. Currently there is no universally effective treatment for sarcoids and if treatment fails the sarcoids will often come back worse.
However, research that was given funding by The Horse Trust offers a potential ray of hope for owners of horses affected by sarcoids. The research was published in Virus Research journal earlier this year.
The research, which was led by Professor Lubna Nasir of the University of Glasgow, found that by inhibiting the activity of a particular viral protein within sarcoid cells, the amount of viral DNA in the cells reduced. This led to a reduction in the growth of the sarcoid cells and caused the cell to die by Programmed cell-death (PCD). The researchers believe that PCD occurs because the sarcoid cells become reliant on the virus.
Professor Nasir said: "This could potentially be a major breakthrough in the treatment of sarcoids. We are now seeking funding to use this technique in clinical trials on horses that have sarcoids."
The research team inhibited the activity of a viral protein called E2, which is needed by BPV to replicate. They used a novel approach termed 'gene silencing' to suppress the activity of the gene that codes the E2 protein. The research was carried out in vitro on fibroblast cells, which had been cultured from sarcoid tissue removed from animals during surgery.
As this research was carried out in vitro, the researchers will now need to see if they can replicate the results in vivo, by developing a way of targeting the sarcoid cells in horses.
"One of the challenges with gene silencing is administering it within clinical setting - as you need to get molecules into every cell. As sarcoids are on the surface of a horse, we think administration should be relatively easy - potentially by injecting or applying a cream to the sarcoid," said Professor Nasir. "If we are able to successfully develop this technique it would be a non-toxic and easy to administer treatment for horses affected by this distressing condition."
Nasir's research could also have an impact on the treatment of lesions in cattle, which are also caused by BPV. Around 50% of cattle in the UK are estimated to have lesions. It may also help with the treatment of Human Papillomavirus (HPV) infections in humans. HPV, which is similar to BPV, can lead to various cancers in humans including cervical and vaginal cancer.
Paul Jepson, Chief Executive and Veterinary Director of The Horse Trust said: "We are really excited that the research we have funded could lead to a major breakthrough in the treatment of sarcoids."
The Waltham Equine Studies Group has announced the results of two pieces of research designed to improve understanding of the best nutritional support for older horses, whether they are healthy or diagnosed with Pituitary Pars Intermedia Dysfunction (PPID or Cushing's).
The first study: A comparison of nutrient digestibility between adult and aged horses, conducted by the Department of Large Animal clinical Sciences and Animal Science, Michigan State University and The Waltham Equine Studies Group, confirmed (in contrast to earlier work) that there was no difference in digestibility between healthy adult and aged horses when fed a variety of common equine diets.1
In the second study: Characterisation of the faecal bacterial community in adult and elderly horses fed a high fibre high oil or high starch diet, the Institute of Biological Environmental and Rural Sciences, Aberystwyth University, The Waltham Equine Studies Group and Michigan State University used the same horses as the previous study but this time looked at their gut microflora. The results showed that although no significant differences in individual species of bacteria were found, ageing was, however, associated with a reduction in bacterial diversity. This, say the authors, may in part explain why older animals can be at increased risk of intestinal disturbances.2
An abstract that summarised part of the Waltham Equine Studies Group's work on the effect of additional supplementation on aged horses with and without PPID was presented at the 2nd Dorothy Havermeyer Geriatric Workshop in the USA last November.3 This work, carried out in conjunction with Dr Amanda Adams at the University of Kentucky showed that age is key in influencing inflammation and metabolism rather than whether the horse is PPID positive or not.
Professor Pat Harris, head of the Waltham Equine Studies Group, said: "For the parameters we monitored, the research showed that it is being old that is the issue, rather than having PPID."
Clare Barfoot RNutr and the research and development manager at Spillers said: “This should give us a better understanding of the effects of diet and age on metabolism in order to determine optimal nutrition for the senior horse. Preliminary work suggests that this new research may change the way we think of feeding the older horse. Waltham’s work continues to ensure that Spillers feeds remain at the forefront of equine nutrition, for the better health of horses everywhere.”
References
The aim of the study was to assess the adverse effect profile of each individual AED by analysing all available data that has been published for each specific AED and then evaluating how reliable the data was. The study was published in BMC Veterinary Research (DOI: 10.1186/s12917-016-0703-y).
To do this the researchers gathered, screened and assessed all the information published in peer-reviewed journals and publications. The individual studies were then evaluated based on the quality of evidence, study design, study group sizes, subject enrolment quality and overall risk of bias. The results, say researchers, now provide a new and more objective insight into the tolerability and safety of the AEDs.
Co-author of the study, Marios Charalambous, said: "We recruited systematic and statistical methods to combine, compare and summarize the results of independent studies and, therefore, create more objective and reliable conclusions based on the current evidence. It was a time-consuming, demanding and challenging process, but we are sure that we provide the clinicians now with essential information which they can use for daily practice."
By reviewing, assessing and untangling the vast amounts of data, the researchers found that much of the evidence for the medical treatment of canine epilepsy was based on subpar reporting of adverse effect and in studies that were below the expected standard. They say that only in recent years can the quality of studies carried out be considered adequate.
Professor Holger Volk, Clinical Director of the RVC Small Animal Referral Hospital and Professor of Veterinary Neurology and Neurosurgery (pictured right), said: "Not only does this study offer a new perspective on the management of canine epilepsy, but also highlights the importance of the need for trials which provide high quality evidence in order to have more reliable and objective results about the safety and tolerability of the AEDs in veterinary medicine."
Dr. Dave Brodbelt, Senior Lecturer in Companion Animal Epidemiology, added: “This is a valuable addition to the body of literature on canine epilepsy, highlighting safety issues and adverse events related to its management and adding further depth to the evidence base relevant to practicing vets."
The company has been gathering information on the health, wellbeing and life expectancy of hundreds of thousands of dogs since 2014.
Sean McCormack (pictured right), Head Vet at tails.com, said: “As a vet in practice, you gain an understanding of general animal issues and trends. But what this data can do is look over hundreds of thousands of dogs, unpick all of the nutritional, breed and age-related data we’ve collected over time, and then provide an insight-rich window into the best possible way to care for our dogs.
“We’re really just scratching the surface in terms of what we have at our disposal. There’s real potential for Data Labs to fundamentally change the way that we view dog nutrition and dog health going forwards.”
According to the company, the database has already revealed that:
Lorna Brightmore, Lead Data Scientist at tails.com, said: "Even at this early stage, we are finding strong associations between a number of health factors and longevity and our conclusions will only become stronger over time.”
The first major milestone of Data Labs will be the publication of tails.com’s first peer-reviewed scientific paper.
The paper will detail the effects of body weight, body condition, gender and neutering on the longevity and health of dogs, with further scientific papers planned for publication in the coming months and years.
For more information, visit www.tails.com/gb/data-labs/.