Kaminox contains potassium gluconate and B-vitamins to help dogs affected by hypokalaemia.
Originally released as an oral liquid supplement, Vetplus says this new powdered formulation offers a more concentrated level of potassium for larger pets or those that require a higher dose.
Kaminox sachets are sold in packs of 30, with a scoop provided for easy administration.
Meanwhile, the liquid supplement is available in 60ml and 120ml bottles.
www.vetplus.co.uk/products
Those who pay their fees after 30 April 2017 will be charged an extra £35 to renew their registration while those who have not paid by 31 May 2017 will be removed from the Register.
You will also need to confirm your registration details, confirm you've met the RCVS requirement for continuing professional development of 105 hours over a three-year rolling period and disclose any new or previously undisclosed convictions, cautions or adverse findings.
The annual renewal can be completed by logging into the ‘My Account’ area of the RCVS website (www.rcvs.org.uk/login). For those members who do not have a valid email address, or have requested a hard copy of the renewal form, a form has been sent by post.
Any veterinary surgeons who have not received their annual renewal form or security details for the ‘My Account’ area by 7 March should contact the RCVS Registration Department on 020 7202 0707 or registration@rcvs.org.uk as soon as possible.
Those with queries about paying the annual renewal fee should contact the RCVS Finance Team on 020 7202 0723 or finance@rcvs.org.uk
BSAVA’s client information leaflets are designed to be used as part of the veterinary consultation and provide information to help owners understand what is involved in a procedure or examination, including the reasons for it, the preparation required, any associated risks and what happens during and after the procedure.
They are available in a PDF format which can be printed and stamped with the veterinary practice details or emailed to clients.
Elise Robertson, ABVS American Board-Certified Diplomate Feline Practice and author of the endoscopic Client Information Leaflets, said: ‘The client information leaflets were created due to the need for accurate and reliable information from reputable sources."
BSAVA’s Head of Publishing, Ian Mellor, said: "This new factsheet brings our total number of client leaflets to 178. Our client leaflets have been downloaded more than 10,000 times in the past year and are an important part of our drive to improve the health and welfare of small animals by providing practical resources to the veterinary profession.’
The new leaflet is available via the BSAVA Library (https://www.bsavalibrary.com/content/cilgroupprocedures).
Access to the entire range of client information leaflets (including canine and feline behaviour, exotic pets and medicines) is available for an annual subscription of £40; BSAVA members have access to these leaflets as one of their membership benefits.
BSAVA welcomes suggestions for new topics to cover in its client information leaflets.
Send your ideas to publications@bsava.com.
The event, which is being organised by Colin Whiting MRCVS and his wife Lizzy (also MRCVS), is taking place at Killaworgey Farm, Black Cross, Newquay, TR8 4LU
Performing on the outdoor stage at the event are the Ceilidh Band and Spit Roast, a covers band.
Catering includes a licensed bar, wood-fired pizzas, log-roasted chicken, pulled pork burritos, pasties and cream teas.
There'll be a quiz night, fancy dress and an outdoor showing of the film Trainspotting.
And if all that weren't enough, you'll be just a stone's throw from Newquay and its nearby beaches, and about 30 mins drive from the Eden Project.
Colin said: "The whole vet world family is welcome.
"We've got people coming from Liverpool vet school straight from rotations, practices bringing their EMS student along: bands, bar, party field, outdoor roasts and burritos, indoor pasties and wood-fired pizzas, and - to cap it all - a 6-shower, 8-loo toilet block newly completed for the camping field, with a 2-metre urinal in the gents as well, but that's not so much of a selling point...
"Visitors are very welcome to come earlier or camp longer too; there's a warm welcome for all at Killaworgey."
Fore more information, visit: https://www.killaworgeyfarm.co.uk/
It's the final call for comments on the draft new RCVS Code of Professional Conduct for Veterinary Surgeons, as the consultation closes on Friday, 24 June 2011.
The new draft Code, which is intended to replace the existing RCVS Guide to Professional Conduct for Veterinary Surgeons, was produced by a Working Party set up by the RCVS Advisory Committee.
The new Code is a short, principles-based document using the Federation of Veterinarians of Europe's Code of Conduct as the starting point. It will be supported by additional advice on specific areas of veterinary practice or issues, for example, clinical governance.
New requirements in the Code include compulsory continuing professional development, the RCVS Health Protocol and more on clinical competence. It also contains an updated declaration to be made by veterinary surgeons, which gives increased emphasis to animal welfare.
The new Code, together with the consultation paper, can be downloaded at www.rcvs.org.uk/codeconsultation.
Comments, which are welcomed from the profession and the public, should be sent by email to Christopher Murdoch, Secretary to the Guides Review Working Party, at c.murdoch@rcvs.org.uk by Friday, 24 June 2011.
A separate consultation will open shortly on a draft RCVS Code of Professional Conduct for Veterinary Nurses.
The RCVS has announced the appointment of Gordon Hockey as its Head of Legal Services/Registrar.
Gordon, who was previously Head of Professional Conduct and Assistant Registrar, has latterly been Acting Registrar, following the departure of Jane Hern in November 2011 and the arrival of Nick Stace as Chief Executive on 3 September.
A qualified barrister and pharmacist, Gordon has been at the RCVS for the last 14 years.
His is a new role created when the old post of Registrar and Secretary was effectively split into two: Chief Executive and Secretary, and Head of Legal Services/Registrar.
Nick Stace said: "I am delighted that Gordon's is my first appointment as Chief Executive, and I am grateful that he held the fort so well for the last nine months. I look forward to working with him to ensure that the RCVS is in the best shape possible to meet the needs of the public and the veterinary team."
Jacqui Molyneux, RCVS President said: "We have a very strong team to take the RCVS forward. Nick has joined us with leadership experience, consumer expertise and new ideas and impetus; Gordon consolidates this with his legal expertise and experience of the veterinary profession and the RCVS. I look forward to working with them both."
The appointment is subject to formal ratification at the November meeting of Council.
Carried out by the Royal Veterinary College (RVC), the Animal Health Trust (AHT) and Rossdales Equine Hospital, the study also revealed that the groups particularly at risk were native pony breeds and their crosses, as well as horses and ponies with a history of laminitis and those with lameness or soreness after routine hoof care.
This research, funded by World Horse Welfare, comes from the first ever online study that collected information on laminitis from a group of owners in real time.
The researchers say that the study is also the second largest to identify weight gain as a risk factor for laminitis. Data was collected from the owners of 1,070 horses and ponies in Great Britain, who reported their animal’s management, health and estimated weight via online questionnaires for 29 months.
Owners were encouraged to use a custom weight tracking tool designed by the study/research team to help regularly track changes in their animal’s weight and body condition. The uptake of this tool was high, with over half of participating owners using it.
The tool is freely available at: www.aht.org.uk/research/lameness/laminitis.
Other study findings included:
A high risk of laminitis was present in horses shod or trimmed at intervals of more than 8 weeks, and in those that took a long time to return to soundness after a bout of laminitis.
Diet, grazing management and health were factors closely associated with the development of laminitis and will be the subject of future investigation.
Researchers also noted that weight gain often occurred unintentionally, even when owners were aiming for their animals to maintain or lose it. This reiterates the need to consistently record weight and body condition in order to prevent undesirable weight gain.
Dr. Dee Pollard of the AHT, one of the study’s chief authors, said: "This is one of the largest, and the first, online laminitis studies where we collected regular information from the same group of owners in real-time. We assessed the relationship between laminitis and many potential management and health factors and identified those more likely to be present before a laminitis episode was reported.
"We now have good evidence to develop laminitis prevention guidelines, and a number of different avenues to explore in the future. We cannot emphasise enough how important systematic and regular weight and body condition monitoring are. It’s very easy to miss weight gain when you are just relying on your eyes and you see your horse or pony every day. You need to get hands on, feel for the fat deposits and take measurements, remember the figures don’t lie!"
Reference
The College says that 1CPD has been designed to facilitate the new outcomes-focused CPD model which was introduced in 2020 and becomes mandatory from 2022.
An important part of this new model is reflection, so 1CPD encourages vets to reflect on the quality, relevance and impact of their CPD activities.
Dr Linda Prescott-Clements, RCVS Director of Education said: "Although the outcomes-focused element of these changes won’t become mandatory until January 2022, we recommend that you incorporate reflection in your cycle of planning, doing and recording CPD as soon as possible, and our new 1CPD app makes this much easier to do than before.
"Research has found that reflection enhances the quality, impact and relevance of CPD as professionals consider what they have learned, how they will apply their learning and how it will improve their practice. To support this CPD model, which research has shown has a positive impact on both professionalism and patient outcomes, the 1CPD platform facilitates reflection by allowing you to record your reflective notes on your recorded CPD activities, through a variety of means including text, audio or uploading a document."
The old PDR was taken offline last Friday and all of the data saved in the PDR has been transferred to 1CPD.
The 1CPD app is now available for both Apple and Android devices, available on and off line, and through a new dedicated website, all of which is now accessible using the same credentials used to access My Account.
Richard Burley, RCVS Chief Technology Officer, said: "1CPD provides a range of enhancements to RCVS’ previous offerings in this space and represents an important step forward in the College’s digital approach. Built on the latest best-practice technologies, it improves on every aspect of our previous approach to CPD support, delivering the first stage of a new, integrated, career-long CPD support capability for members.”
The launch of 1CPD also coincides with a change to the way that the College assesses CPD compliance, moving to an annual CPD requirement of 35 hours a year for veterinary surgeons and 15 hours a year for veterinary nurses.
More information on the CPD changes, along with accompanying resources, can be found on the RCVS website: http://www.rcvs.org.uk/cpd2020.
So that practices can make sure everyone in their team is aware of the changes, the RCVS has also produced a poster which can be downloaded at: https://www.rcvs.org.uk/news-and-views/publications/cpd-poster/.
For more information, contact the Education team on 0203 795 5595. For technical advice about 1CPD, email the RCVS at onecpd@rcvs.org.uk.
The company says the results of the survey of puppy dental health will be shared with industry experts to help advance understanding and evaluate the future impact on veterinary practices.
Veterinary professionals can also sign up for a free webinar on puppy dental disease led by Head of the Dentistry and Oral Surgery Department at the Royal (Dick) Vet School, Ingrid Tundo on 28th April at 7.30 pm at https://veterinarywebinars.com/register/puppy-dentistry-malocclusion.
Cat Henstridge MRCVS, who is fronting the campaign said: “I’m very pleased to be helping to raise awareness of the VisioCare Puppy Tooth Census and this important issue.
"It is so important for all of us in the profession to be helping to identify disease patterns and the scale of the problem. It also provides us with a great opportunity to involve our clients and start discussions about the importance of good dental care.”
VisioCare says the Puppy Tooth Census only takes a few minutes to complete and can be filled in for individual cases or healthy puppy mouths.
Every veterinary respondent will be given a free pack of educational materials to use in the consulting room, including state-of-the art digital animations and dental images that can be used to enhance client communication around the topic, together with explainer videos and puppy owner fact sheets and leaflets.
In addition, each month for the next three months, responses will be entered into a prize draw for the chance to win a £50 John Lewis gift voucher.
For further information or to complete the census for a case, visit: http://www.visiocareservices.co.uk/puppy-tooth-census.
Defra has been roundly criticised in the media today for reportedly spending £181,000 on redesigning its website.
Here's the old website. Apparently deemed 'too agricultural' for its use of brown.
And here's the new one:
A vast improvement, and depending on what the £181,000 bill included, it may not have been as overpriced as it sounds.
Either way, it prompted a great quip from Tory environment spokesman Nick Herbert: 'At least it's now clear that, like the rest of the country, Defra has gone off Brown.'
Virbac Animal Health has launched an interactive didactic atlas on canine dermatoses for practitioners at www.virbacderm.com.
According to the company, the site offers an original approach to a dermatological investigation, with straightforward flowcharts and enlarged schematics of canine skin.
Product manager Chris Geddes said: "The site brings to life many of the topics covered in the clinical handbook, and may prove particularly valuable as client educational tools. It contains several free educational tools for the dermatologist in general practice."
He added: "Virbacderm.com is already proving extremely useful both for investigating a case and also to boost online CPD. Every aspect of an investigation is included, from effective history taking, to the appropriate time for a biopsy.
"There is also an important section on what is normal for a dog. There's some interesting data on the differences between canine and human skin, and why even "baby shampoo" is not appropriate for use on dogs."
The site also provides compliance tools for clients that are free to download, together with materials provided from Virbac Territory Managers. Chris said: "These aim to ensure that the treatment course prescribed by the vet is in fact being followed correctly and fully - surveys suggest that perhaps only 50% of clients do so."
The RCVS played a proactive role in Mr Keniry’s arrest and trial after its Chief Investigator, Michael Hepper, was alerted to the fact that he was working at a veterinary practice in Taunton, Somerset.
Within 24 hours Mr Hepper reported this to Avon & Somerset Police and attended the practice with officers to assist in Mr Keniry’s identification and arrest. Mr Hepper continued to assist with police investigations and gave a witness statement.
Eleanor Ferguson, RCVS Registrar, said: "We are grateful to the veterinary professional who voiced her suspicions to us, to our Chief Investigator who reacted quickly to confirm his identity and report the matter to the police and to Avon & Somerset Police for taking matters forward so quickly.
"Mr Keniry was known to the RCVS as we have assisted in previous police investigations into him for similar offences. As with recent cases Mr Keniry impersonated a legitimate member of the veterinary profession using fraudulent documentation and this is why we have previously published photographs of him to raise awareness with veterinary practices and to try and stop him being employed in the future.
"We believe that Mr Keniry is a threat to animal health and welfare. He is a repeat offender and so we are glad that he has been handed a significant custodial sentence.
"While sophisticated and convincing fraudsters like Mr Keniry can be very difficult to prevent, we would urge veterinary practices to be vigilant. For example, we recommend that potential employers contact our Registration Department to make checks, always interview a potential employee face-to-face, ask to see supporting identity documents, prepare questions which confirm where and when they studied, obtain references and, if they are employed, mentor the new member of staff to oversee their performance.
"For members of the public we recommend that, if they have concerns about the legitimacy of their veterinary surgeon or veterinary nurses, they talk to someone else in the practice about their concerns or contact us so that we can make further enquiries. Members of the public can also check on the status of veterinary professionals using our Find a Vet search tool: www.findavet.org.uk.
"We would like to emphasise that cases such as that of Peter Keniry are, in our experience, extremely rare. There are around 23,000 veterinary surgeons registered to practise in the UK who are fully trained professionals dedicated to upholding and improving the health and welfare of animals under their care. We don’t believe that the unprecedented actions of this one fraudulent individual should in any way undermine the confidence and trust that animal owners place in their veterinary team."
Open to anyone working in a veterinary setting at any stage of their career, the competition rewards teams and individuals (clinical and non-clinical), who have achieved better outcomes through QI initiatives for patients, clients, the business or the working environment.
Individual winners will be crowned 'Knowledge Champions' and one team will become RCVS Knowledge’s 'Champion Practice'.
Each winner will also receive a £250 reward, tickets to the awards ceremony next calendar year and the opportunity to work with RCVS Knowledge to further promote their quality improvement work.
Candidates can nominate themselves or others for an award.
If you want to nominate a colleague, the deadline is 17thOctober. The deadline to apply on your own behalf or that of your team/practice is 29th November 2019.
Full details are available online: bit.ly/KnowledgeAwards.
Executive Director of RCVS Knowledge, Chris Gush said: "The 2019 awards shed light on the very good work those in the profession are doing to continually enhance quality, so we are delighted to bring the competition back for 2020.
"It is a great opportunity for individuals and teams to showcase their quality improvement initiatives. Whether it is clinically focused or aiming to improve procurement, we are keen to hear about the work that is underway."
Last year's awards highlighted inspirational QI projects such as a drugs audit that led to a ten-fold improvement in usage discrepancy; a quarterly clinical audit that enhanced nursing expertise and trust from veterinary surgeons; and the introduction of guidelines that coincided with the subsequent treatment of 2,639 additional animals.
The case examples submitted by each winner are available to download for free:
'Champion Practice' Vets Now Macclesfield for its anaesthesia audit.
'Knowledge Champion' Louise Northway RVN, Wendover Heights Veterinary Centre, for her anaesthesia audit.
'Knowledge Champion' Alison Thomas MRCVS, Blue Cross, for her case study: Creating clinical guidelines.
'Knowledge Champion' Angela Rayner MRCVS, CVS Group plc, for her case study: Controlled drugs process audit.
For more case examples and QI resources, visit: bit.ly/QIKnowledge
Susan Little, pictured left, talks about ‘Low Stress Management of the Diabetic Cat’, Professor Ian Ramsey gives his: ‘Top Ten Tips on Diabetes on a Budget’, and Grant Petrie presents: ‘Patients in Lockdown’: principles to manage diabetes remotely.
John Helps, Senior Veterinary Advisor at MSD Animal Health said: “Pet diabetes continues to be of increasing importance in the UK. Research has shown that up to 20% of diabetic pets die, or are euthanised, within a year of diagnosis1. No-one wants to these figures rise further because of the recent challenges so the topics covered are all particularly relevant to veterinary practice teams at this time.”
To watch the presentation, use this memorable link: https://onlinexperiences.com/Launch/QReg/ShowUUID=ADB18692-C804-40FD-B8C3-5D97C7DBC333&LangLocaleID=1033.
Further information for veterinary professionals from: https://www.msd-animal-health-hub.co.uk/ahp/caninsulin/tools.
For pet owners, the Caninsulin website offers more information about diabetes: www.caninsulin.co.uk.
Since qualifying as an RVN in 1998, Georgina, aka George, has had a number of veterinary management roles, including Head Nurse, Business Support Manager and Regional Operations Manager.
She is currently Practice Director for Irby and Neston Vets in Cheshire.
George joined the VMG Board in 2016 and takes over as President from Richard Casey, who becomes Senior Vice President of the association.
Stuart Saunders, Practice Manager at Devon-based Selworthy Vets, becomes Junior Vice President.
All will serve a one-year term.
George said: “Becoming a manager or leader has an impact on the individual, but has an even stronger impact on the work and day-to-day experience of those around them.
"These roles therefore bring with them a great responsibility to do them well.
“We know from our members that the support, teaching, coaching and other resources that the VMG offers are making a positive difference and I’m particularly excited to take on the presidency following the recent launch of our Certificate of Veterinary Leadership & Management, an accredited taught qualification.
"I believe rigorous qualifications are the most effectively way to create the 21st century leaders and managers the veterinary sector needs.
“During my presidency, I will continue to focus on extending the range of support and help we offer to leaders and managers."
The model for the forecast was developed by the College with the Institute of Employment Studies using data from the RCVS Registers, the 2019 and 2024 Surveys of the Professions, Office for National Statistics data for projected economic growth and the PDSA’s Animal Wellbeing (PAW) Reports.
However, the model does not take account of the impact of the increasing costs of veterinary care on pet ownership trends, the full effect of which may not yet have been felt.
The main predictions of the model are:
Lizzie Lockett, RCVS Chief Executive Officer, said: “In 2021, there were clear concerns about there being a workforce crisis within the veterinary professions, and while that certainly seemed to be the case, and is likely to continue to be so in the short-term, according to this model the future picture for the professions looks much better in most areas of veterinary practice.
“However, government service/public health looks to be an area where there is still a significant shortfall in supply, which is concerning considering the importance of government vets in food safety, disease prevention and international trade and we are willing to continue to work with government to find ways to remedy this shortfall.
“We are aware that there may be some concerns about the implications of the model, particularly concerning the potential oversupply of veterinary nurses.
"While we stand by the robustness of the data, demography is not destiny, and with the planned enhancement of the veterinary nurse role, and the likelihood of suppressed demand due to prior shortages, it is likely that the number of veterinary nursing roles will expand to encompass the number of veterinary nurses available to work in it.
“Finally, we are aware that there are also some limitations to the model in its current form, for example, in terms of regional data.
"This is a work in progress, and we will continue to update and improve the model as and when new data allows.”
The workforce modelling report is available to download from www.rcvs.org.uk/publications
It was alleged that in September 2015, she had acted inappropriately by striking a Shih Tzu/Toy Poodle cross puppy called Arnie on his head.
The hearing commenced on Tuesday 3 January 2017 with evidence being given by the owner of the animal ("TC"). However, the corroborating witness, who was also the complainant in the case, failed to attend the hearing to give evidence.
Efforts were made by the College to contact the complainant and remind her that she had been summoned to appear before the Committee – however, she still chose not to attend the hearing to give evidence. In response to her non-appearance the Committee decided that her written evidence was inadmissible as there would be no opportunity to cross-examine her about the discrepancies between her account and that of TC.
Miss Faulkner’s counsel then made an application to the Committee that the College had failed to sufficiently prove its case to the requisite standard such that it would not be necessary for her to adduce any evidence in her defence. The Committee granted this on the grounds that there were clear inconsistencies in the evidence given by TC at different stages of the investigation and during the hearing itself.
Chitra Karve, chairing the Committee and speaking on its behalf, said: "The Committee was unable to conclude that TC was a reliable witness. Given TC’s centrality to the case the Committee is unable to be satisfied so that it is sure that her account of events as outlined in her oral evidence is accurate. Accordingly, the Committee is not satisfied that the College has proved to the requisite standard that the respondent did in fact strike Arnie to the head as alleged.
"Accordingly, the Committee accepts the submission made by the respondent that the College has not adduced sufficient evidence upon which it can find the facts alleged in the charge to be proved. Therefore, it is not necessary for the Committee to consider this matter any further. There is no case for the respondent to answer."
Merial - maker of the canine NSAID Previcox - has launched a campaign to raise awareness of the prevalence of canine osteoarthritis amongst dog owners in the UK.
Previcox Product Manager Claire Edmunds said: "We know that approximately 20% of adult dogs suffer from OA, but less than 25% of these dogs are treated with NSAIDs in the UK. That's one in five dogs that may be enduring the pain and discomfort of a condition that can be improved. Most owners will put their dog's loss of mobility down to old age, however, our aim with this campaign is to raise awareness of this condition with pet owners to encourage them to seek help from their vet for their pets, and assist vets in promoting treatments for this condition."
Merial says veterinary surgeries can take part in the campaign in five easy steps:
The following campaign materials are available:
For more information about the Missing Dog Campaign, please contact your Merial Territory Manager on 0870 6000 123.
The judging panel, comprising BVA President Anna Judson, RCVS President Sue Paterson, National Veterinary Lead Ruminant and Equine at Zoetis UK Ally Ward, and last year’s award winner Hannah Hunt, selected the finalists based on their inspirational work which includes supporting clients and colleagues, providing outstanding and consistent care for patients, inspiring others and giving back to their community, championing causes in the profession and going above and beyond the normal call of duty.
Rebecca, who graduated from Bristol in 2015, was nominated for her work co-founding Veterinary Education Malawi, an animal welfare charity which provides free veterinary services to low-income communities and educational support both to the para vets in the country and to the Lilongwe University of Agriculture and Natural Resources (LUANAR), its only vet school.
Henry, a commercial poultry and gamebird vet, was nominated for his work tackling outbreaks of avian influenza and encouraging other young vets to take up roles in the poultry industry.
Henry is also a European College of Poultry Veterinary Science resident, mental health first aider and trustee of regional rural mental health charity You Are Not Alone (YANA), co-lead of his practice green group, and deputy rotation lead for the new RVC poultry rotation, which takes its first students in 2024.
Camilla is an equine vet who was nominated for her dedication to promoting the veterinary profession, equine welfare, and for her work setting up the ambulatory equine practice, Perth Equine Vets.
A Glasgow 2015 graduate, Camilla set up Perth Equine Vets in 2020 growing it into the three vet practice it is today.
She organises frequent events, most recently a “get into vet school” day for upcoming vet students, which saw more than 40 potential senior school pupils attend, alongside educational demos for owners to increase their own knowledge. She also regularly creates blogs and videos on the practice social media accounts which helps horse owners learn essential skills.
BVA President Anna Judson said: “BVA’s Young Vet of the Year showcases exceptional vets from across the UK making an invaluable contribution to the profession.
"This year we have been blown away by all the incredible nominations, but these three young vets really stood out for their contribution to their fields and their commitment to their unique causes and passions.
"Congratulations to all of the finalists, you are a credit to the veterinary profession and we know you have bright futures ahead of you.”
The winner of BVA Young Vet of the Year will be announced at BVA's Gala Dinner taking place at the London Vet Show on 16th November.
Photo: R-L, Camilla Church, Henry Lamb and Rebecca Hampson
A research project funded by The Horse Trust has made important discoveries about how two peptides regulate the inflammatory response in horses. This knowledge could help with the development of improved anti-inflammatory drugs, which are used to treat a wide range of conditions in horses.
The research project was led by Professor Fiona Cunningham at the Royal Veterinary College in Hertfordshire and Dr Karen Rickards at the Donkey Sanctuary in Sidmouth, assisted by Dr Andrew Brooks at the RVC, and by Dr Kirstie Pickles, now at the Royal (Dick) School of Veterinary Studies in Edinburgh.
Inflammation is associated with a wide range of equine diseases, including recurrent airway obstruction, laminitis and sweet itch. Anti-inflammatory drugs, such as glucocorticosteroids, mainly work by blocking the formation and/or actions of compounds produced in the horse's body that cause inflammatory responses. However, these drugs are not always effective and can have unwanted side effects.
This research, funded by The Horse Trust, aimed to find out more about two naturally-occurring peptides - chains of amino acids that are shorter than proteins - known as annexin-1 and CXCL8. Both have been shown to affect the inflammatory response but little research has been done on their effects in horses. In the long term, knowing more about these compounds could help in the development of new anti-inflammatory drugs with fewer side effects.
During inflammation, neutrophils (a type of white blood cell) stick to the cells lining blood vessels and migrate into inflamed tissue, where they ingest and break down harmful agents. Using techniques that mimic these events, CXCL8 was found to cause adherence and migration of horse neutrophils. However, when it was used in combination with another pro-inflammatory substance, neutrophil migration and adherence were markedly decreased. This suggests that attempts to reduce inflammation by blocking the actions of CXCL8 might not be as beneficial as had been thought.
At the start of the project, the researchers had no information about horse annexin-1, other than its gene sequence, so their first step was to develop a method to detect the peptide in white blood cells. They established that it was present and, as horse annexin-1 has not yet been synthesised, they used a synthetic peptide derived from annexin-1, Ac2-26, to look at the effects on horse neutrophils.
They found that Ac2-26 decreased neutrophil adherence and migration in response to other pro-inflammatory compounds, although at high concentrations the peptide itself caused some cell activation, thereby increasing inflammation. They also found that dexamethasone (a glucocorticosteroid) increased the levels of annexin-1 in cells, indicating that, as in humans, this class of drugs is likely to act in part through the formation of annexin-1.
These findings suggest that the use of compounds which mimic the actions of annexin-1 may have limitations as anti-inflammatory drugs. As glucocorticosteroids partly work by forming annexin-1, further research is needed in order to find out how annexin-1 will act in the horse's body and establish how its formation contributes to the beneficial effects of these drugs.
Professor Cunningham said: "This Horse Trust-funded research has resulted in some very interesting findings about how inflammatory cells are regulated in horses. The receptors that annexin-1 and CXCL8 act upon could be targets for new equine inflammatory drugs, but more research is needed first to fully understand their actions and how they produce these effects."
The team's research has been accepted for publication by the journal Veterinary Immunology & Immunopathology.
Novartis Animal Health has announced that it has assumed marketing responsibilities for the joint health supplement Cosequin in the United Kingdom and Ireland.
Cosequin, which contains glucosamine and chondroitin sulfate, is available in a range of presentations for dogs, cats, and horses.
The product, which was previously marketed by MSD, is the leading joint health supplement among veterinary surgeons in the US and Europe.
Novartis says Cosequin is an important addition to its Orthopaedic Health Category, which in 2009 introduced Onsior (robenacoxib), the first tissue-selective pain relief for cats and dogs.
Gaynor Hillier, General Manager UK & Ireland Novartis Animal Health said: "Our strategic intent is to expand our presence in orthopaedic health to address prevention, diagnosis, and treatment in a more comprehensive manner. Cosequin represents an important step toward achieving this objective".
Cosequin is available from Novartis Animal Health in the United Kingdom and Ireland, from licensed veterinary wholesalers. For more information on Cosequin, contact your Novartis Animal Health Territory Manager.
Brand Manager Dr Amy Scott said: "Because pain is often very difficult for owners to spot, the website highlights some of the common signs that indicate their cat or dog is suffering.
"We have also included a range of additional measures that owners can take to improve the quality of life and maintain the joint health of their pet once Metacam has been prescribed. These include weight management, regular and gentle exercise and alternative therapies such as hydrotherapy or the use of joint supplements such as Seraquin."
The website highlights common painful conditions such as arthritis, as well as more acute scenarios such as post injury or surgery. It also describes the changes in behaviour owners should be aware of that could indicate their pet is in pain, for example reluctance to exercise, change in appetite, displays of aggression or depression.
Amy added: "The correct use of NSAIDs is also an important consideration for effective pain management. To help with this, the website contains a section on Metacam administration for owners, featuring a short video on accurate dosing and treatment."
Designed to help veterinary practices save clients' time and improve compliance, VetsDeliver supplies Bravecto - the company's 12 week flea and tick treatment - with the wormer of the vet's choice, by post.
Before the pandemic, practices registered clients for the service online or during an appointment and clients would have to collect the first treatments from the practice.
In response to the pandemic, however, MSD has made now it possible for clients to register from home and get their first treatments sent by post.
Amanda Melvin, Marketing Manager for Companion Animals at MSD Animal Health said: "We are all in unchartered territory and we appreciate the pressure veterinary teams are under to continue to care for their clients and local pet community.
"Many businesses are having to add new services to support online facilities and home delivery, and for vets there is also now a need to reduce footfall into practice while still generating income. Making sure effective parasite control is available will help improve compliance as temperatures rise and the risks to the health of our pets increase. It's one less thing for you and your clients to worry about."
For further information, contact your MSD Animal Health account manager or go to www.msd-animal-health-hub.co.uk/vetsdeliver.
He takes over the role from Huw Griffiths at the end of BEVA Congress 7th -10th September 2022. Roger Smith becomes President Elect.
Following graduation from The University of Bristol in 2001, David worked in farm animal and equine practice in Somerset before completing an internship at Liphook Equine Hospital.
A three-year Horserace Betting Levy Board residency at The University of Glasgow and Liphook Equine Hospital enabled him to train as a specialist in equine internal medicine and to gain a masters by research into equine asthma and an RCVS certificate in equine medicine.
David spent several years at Liphook Equine Hospital in Hampshire and had spells at The Royal Veterinary College, London and Charles Sturt University in Australia before moving to Rainbow Equine Hospital in Yorkshire where he led the internal medicine and laboratory services as a director and subsequently a clinical director following the hospital’s acquisition by the VetPartners group.
David returned to his Westcountry roots in 2020 and now combines work as an independent equine medicine and therapeutics consultant with running the family farm on the edge of Exmoor.
He is chair of BEVA’s health and medicines committee.
During his presidential year David is keen to continue build on his recent work around antimicrobial and anthelmintic resistance as well as expanding BEVA’s global outreach to support more equine vets and have a greater impact on equine welfare.
He said: “I’ve had a great time being part of the profession for the past 20 years and I am now in a position to give something back.
“Huw has driven much activity in the past year around recruitment and retention and I hope to be able to build on this and action results from the recent survey, under Huw’s continued supervision. I am also determined to maintain momentum around BEVA’s antimicrobial and anthelmintic resistance work as well as step up collaboration internationally on these and other projects to extend BEVA’s global outreach.
“Around 99% of the world’s horses are cared for by around 1% of the world’s vets so we are not going to change things overnight; however, BEVA has so much to offer and we should use our resources to support equine welfare, irrespective of where equine vets and their patients live and work.”