MSD Animal Health has launched a new range of vaccination equipment to help sheep and cattle producers administer its portfolio of farm animal vaccines as effectively, cleanly and safely as possible.
The new vaccinators all incorporate the Sterimatic system, which is designed to take the worry out of administering injections to livestock by delivering an accurate dose of any given product, whilst also cleaning and protecting the needle automatically. MSD says the Sterimatic system also decreases the potential for disease transmission, minimises the risk of infection and abscessing at the vaccination site, and reduces needle-stick injuries.
The new equipment is colour-coded and ergonomically designed for comfort in the hand and comes in clear, sterile bags that list the recommended vaccines for use with each vaccinator.
The new vaccinators are now available from animal health product wholesalers.
The National Equine Health Survey is an online snapshot survey designed to uncover common health issues in horses, directly from horse owners themselves. Results of the survey are used to build a picture of equine health and disease in the UK and define priorities for future research, training and education.
Over the past six years the survey, in partnership with the British Equine Veterinary Association, has developed to become one of the UK’s most important endemic disease monitoring initiative. The results are referenced in leading veterinary and equestrian publications and papers and are regarded as valuable benchmarks for our general knowledge of horse health.
Blue Cross Education Officer Gemma Taylor said: "These majestic police horses have taken part in our survey and we hope that they will encourage others to follow suit and be ambassadors for horse welfare.
"The more data we can collect from the National Equine Health Survey the more robust our results will be, helping us to steer equine awareness, education and research to keep our nation’s horses healthier."
Last year survey records were returned for almost 17,000 horses, ponies, donkeys and mules and the six most notable disease syndromes identified.
To take part in the National Equine Health Survey, visit: www.bluecross.org.uk/NEHS
To find out more about Blue Cross’s rescue and rehoming work with horses and ponies visit bluecross.org.uk
The support pack is available now for existing stockists; others can sign up for a pack (whilst stocks last) at the London Vet Show in November, where Lintbells will be at stand U50.
According to the company, an estimated 15% of canine cases presented at first opinion practices are musculoskeletal and cats are also commonly affected.1
The Mobility Matters support materials are designed to help practices communicate the issues to clients, both in the waiting area and consulting room and online. There are also resources to help behind the scenes with setting up the clinics, including the new guide.
Gemma Cunningham, Lintbells Product Marketing Executive said: "We’re keen to bring attention to nurse-led clinics, which are not just great for patients but great for business too. Measurable outcomes include client satisfaction, incremental sales and improved patient comfort or quality of life. We’ve taken into account existing barriers based on what veterinary teams have told us and created the pack to address those needs. Our Mobility Matters referral cards, which help vets signpost clients to the clinics are a brilliant example of how the pack can help teams work more effectively together."
For more information, contact Lintbells on 01462 790886.
Reference
The Veterinary Capability and Capacity Project (VCCP) is co-chaired by the UK’s Chief Veterinary Officer Nigel Gibbens, RCVS Senior Vice-President Dr Chris Tufnell, and BVA Senior Vice-President Gudrun Ravetz. The project board also comprises the CVOs for Scotland, Wales and Northern Ireland, Sheila Voas, Christianne Glossop and Robert Huey, as well as the Animal and Plant Health Agency and the Food Standards Agency.
The project’s objective is to work with the veterinary sector to better understand the UK’s workforce needs and ensure that both the Government and veterinary businesses can continue to protect animal health and welfare, safeguard the food chain and maintain levels of public health and public services, and enable trade in animals and animal products.
The project will include a joint BVA-RCVS submission to the Migration Advisory Committee’s call for evidence on workforce issues post-Brexit. Three working groups have been set up within the project to look specifically at issues of veterinary resources, recruitment and retention.
The UK’s Chief Veterinary Officer, Nigel Gibbens, said: "Leaving the EU provides us with an opportunity to develop gold standard policies on animal welfare. The UK Government is determined to get a good Brexit deal for Britain and Ministers have been absolutely clear we will maintain our world-leading animal welfare standards.
"The VCCP is a great example of collaborative working between government, professional bodies and regulators to prepare for our exit from the European Union.
"I am pleased the Prime Minister has set out the government’s aim to secure the status of the veterinary workforce as a top priority as we leave the EU. The UK’s vets - both Official Veterinarians and those in the private sector - play a key role in protecting our country from endemic and exotic diseases, tackling outbreaks when they occur, safeguarding our animals and tackling global challenges like antibiotic resistance."
Chris Tufnell said: "Since the vote to leave the European Union last year the RCVS has been working in partnership with BVA to highlight to Government and others the potential workforce shortages that could arise from a loss of non-UK EU-qualified vets, particularly in public health work where they tend to predominate. Our position was highlighted in our Brexit Principles published earlier this year and at an event organised by us and the BVA at the Palace of Westminster for MPs and Peers.
"We are very glad that Defra is working proactively with us and BVA to understand the scale of the issues and map out the risks and opportunities and to help us plan for a number of different scenarios in advance so that we do not find ourselves in a position whereby animal health and welfare or public health might be compromised by workforce shortages."
BVA Senior Vice President Gudrun Ravetz said: "Vets provide the foundation for the UK’s high animal health and welfare, and make an essential contribution to the UK economy and wider society. Veterinary teams up and down the country support the UK’s 11 million pet-owning households; not a penny of the UK’s £12.7 billion livestock industry could be realised without vets; and vets are vital to facilitating UK trade, through health certification and controls, so that consumers have confidence in the food safety and welfare of the products they buy.
"Non-UK EU vets make up around 50% of our new workforce each year yet, since the EU referendum; we are facing increasing problems in recruiting and retaining EU colleagues to the UK. The impact of the loss of even a small percentage of the veterinary workforce could have serious repercussions on the practices, communities and industries that vets serve. This profession-wide project is pivotal to ensuring we have a veterinary workforce that can serve the UK’s needs post-Brexit."
The BVA’s Brexit and the veterinary profession report can be found at www.bva.co.uk/news-campaigns-and-policy/policy/future-of-the-profession/brexit/
To read the College’s Brexit Principles in full visit www.rcvs.org.uk/brexit
The Prime Minister has set out the government’s offer for EU citizens in the UK and UK nationals in the EU on their rights and status after the UK leaves the EU: https://www.gov.uk/government/publications/safeguarding-the-position-of-eu-citizens-in-the-uk-and-uk-nationals-in-the-eu
The government’s response to House of Lord’s EU Energy and Environment Sub-Committee’s inquiry into Brexit: Farm Animal Welfare also addresses veterinary capability post-Brexit:https://www.parliament.uk/documents/lords-committees/eu-energy-environment-subcommittee/Brexit-farm-animal-welfare/Gov-Brexit-farm-anim.pdf
Those veterinary surgeons being audited are being asked to share their records for 2013 to 2015 by either allowing the College to access their online Professional Development Record or by sending the RCVS a copy of their CPD record cards. The deadline for sharing records is Friday 14 October 2016.
The audit is focused on six groups:
If any of the veterinary surgeons who have been audited are found to be non-compliant (ie. less than 105 hours of CPD over a rolling three-year period), they will be asked to explain why and send a plan stating how they will make up the hours in order to become compliant.
The College says it is also keen to remind veterinary surgeons that CPD encompasses a wide range of recorded activities, which can be clinical or non-clinical, including private reading/study, webinars, mentoring, clinical audit and discussion groups as well as attending seminars and workshops.
More information about what counts as CPD can be found at www.rcvs.org.uk/cpd
Those with any questions about the auditing process or what constitutes CPD can contact Jenny Soreskog-Turp, Education Officer at the College, on cpd@rcvs.org.uk
Ed's note: Don't forget to claim your VetSurgeon.org CPD certificate detailing time you've recorded reading content and taking part in qualifying discussions on the site. Click 'My Account' and then the 'CPD' tab to view your records and create your certificate.
Novartis Animal Health has launched a 0.5L pack of the anthelmintic Zolvix to make the product more readily available for quarantine dosing, and for the smaller sheep farmer.
Novartis says that because Zolvix is a broad spectrum anthelmintic that has the ability to kill all common sheep gastro-intestinal nematodes, including those resistant to existing treatments, it has a key role to play in quarantine treatment to keep parasite infection down to a minimum.
Simon Harris, Endoparasite Brand Manager at Novartis Animal Health, said: "As the first of the new generation of the Orange or 4-AD anthelmintic group, Zolvix has demonstrated effectiveness in killing worms, even those resistant to other products.
"Sheep farmers are being encouraged to use Zolvix as a quarantine treatment that can significantly reduce worm burdens on farm. I would stress that it is essential guidelines are followed in order to preserve Zolvix's ability to combat nematodes that have acquired resistance to other classes of wormers.
"This new pack size is aimed at farmers who are introducing new stock to their flocks, but will also be convenient for the smaller sheep farmer and smallholders who don't require such a large quantity of product."
Novartis says that because Zolvix is a short-acting anthelmintic, it does not encourage resistance to develop through a long duration of action. It has a high margin of safety so can be used to treat sheep and lambs including pregnant or lactating ewes and breeding rams. Its short meat withhold period of just seven days allows flexibility when marketing lambs.
The wellbeing room is designed to offer staff a comfortable space to relax during breaks, or before or after shifts. It has comfortable seating and a small library of books covering topics such as personal development, mindfulness and stress reduction.
There are also two 'jars of joy' staff can dip into which feature top tips for emotional, mental and physical wellbeing. Employees are also being invited to put forward their own top tips on wellbeing to share with colleagues.
It is hoped that the room will also provide employees with a sanctuary from social media, emails and telephones.
Sounds like a great idea to me, although the library titles look a bit uninspiring for my taste. My ideal wellbeing room would have a few John Grishams on the shelves, limitless music, a Sony playstation, oh, and a minibar.
At the meeting, Simon Biles from Moore Scarrott gave a 30 minute presentation, which was followed by a one hour discussion.
The recording can be watched on VetSurgeon.org here https://www.vetsurgeon.org/001/nonclinical/m/meetings/138080, where you can also claim the time watching towards your annual CPD requirement. Press the 'Claim CPD' red button in the title bar towards the top.
To make it easier to find content that interests you, there are markers on the video timeline.
There is also a forum thread on vetsurgeon.org for further discussion of any of the points raised in the film. See: https://www.vetsurgeon.org/001/nonclinical/f/site-support-discussions/29784/vetsurgeon-zoom-ir35-locums-and-umbrella-companies
For more information about Moore Scarrott, visit: https://www.moore-scarrott.co.uk
John graduated from the RVC in 1973, after which his first job was at a mixed, mainly farm animal practice in Gloucestershire.
From there he moved to a mixed equine/small animal practice in Maidstone before joining Pierson Stewart and Partners, of which he later became a partner and then sole owner. He sold the business in 2018.
John has lectured widely in veterinary dentistry, practice management and cardiology.
He continues to see cardiac cases and carry out breed heart certification.
John invented the word autobiology as it seemed befitting of a life in which animals and plants have been so intricately tied to his work as a veterinary surgeon and his hobbies of gardening and lawn tennis.
He said: "I hope anyone in the profession who is interested in the history of veterinary medicine will enjoy reading how much things have changed in the last 50 years.
"It also has something for anyone interested in practice management, business and finance, not to mention sport.
"I hope it might also help everyone think about their work life balance and mental well being.
"Or you might just enjoy the funny and sometimes tear-jerking anecdotes."
Autobiology of a Vet is priced at £15.99 (hardback) / £8.99 (paperback) / £6.99 (ebook).
For more information, visit: https://www.gbpublishing.co.uk/autobiology-of-a-vet
The Veterinary Marketing Association has announced a Practice Marketing Award, with a prize of £500 worth of CPD, for which entries are now being sought.
The award, which is sponsored by Merial, is open to companion and farm animal practices that can demonstrate effective marketing to their clients during the course of 2012.
For more information, visit: www.vma.org.uk/awards, or email: secretary@vma.org.uk for entry details.
The three presentations, which are between 30 minutes and an hour in length, are aimed at vets but may also be of interest to veterinary nurses. They cover: ‘Topical therapy in canine atopic dermatitis’ and ‘Antimicrobial resistance’ presented by Dr Tim Nuttall and ‘Emotional considerations in dealing with dermatology cases’ by Dr Sarah Heath.
The presentations will be available for download from 7th June 2021, and viewers will be able to enter into a prize draw to win a £50 Love2Shop voucher and a free Cytology Manual.
To pre-register, visit: https://www.thewebinarvet.com/pages/ceva-dermatology-tea-time-top-ups-bite-size-cpd-sessions/
Equistro® has produced a dust-free pelleted presentation of Secreta Pro, following requests from clients. Secreta Pro-Max® was launched to vets at BEVA Congress.
Secreta Pro is a respiratory supplement used to support the bronchial system and natural defences on a long term basis.
For more information on Secreta Pro-Max® and all Equistro products, please visit http://www.equistro.co.uk/, or contact your Vetoquinol representative.
Richard Hepburn MRCVS has launched what is thought to be the world's first equine gastric ulcer study, designed to improve understanding and knowledge of ulceration in performance horses.
Mr Hepburn is conducting the InnerVision study of performance horses, which is being championed by the University of Liverpool, as part of his PhD.
21 appointed practices across the UK are participating in the study, and with each practice scoping between 10 and 20 animals, it will include well over 200 performance horses. Mr Hepburn said: "Gastric ulceration in sports horses is poorly understood, especially compared with racehorses. But what we do know is that it's a very important factor in the performance and well-being of many horses in training and competition."
2012 Paralympic Gold medallist Deb Criddle MBE also attended the launch event. She explained the difference that regular gastroscopy and ulcer management of Paralympic team horses had made to her success. Speaking about her Beijing ride, Pavaroti, she said: "If it weren't for the diagnosis and treatment of Pavaroti's ulcers I don't know what we'd have done. I would probably have had to withdraw him from training, so it made the difference between our partnership continuing or not".
Mr Hepburn expects a prevalence of approximately 60% and, keen to increase understanding of glandular ulceration, participants are being tasked to scope all areas of the stomach, pylorus and duodenum to ensure that every incidence of ulceration is diagnosed and recorded.
He says he is particularly eager to find out more about glandular disease, which hitherto has had little research: "Glandular disease appears to have a very different aetiology to squamous ulceration, and often presents with different signs. We also believe that prevalence of glandular ulceration is most common in sports horses."
"We hope that publication of this study will help all equine vets in their work with performance horses and the quest to prevent and manage equine ulcers," he added.
Merial is supporting the study with management assistance.
Virbac is offering a free Rapid Romanowsky stain kit and Coplin jars to practices buying easOtic and Epi-Otic in a new promotion which runs until the end of October.
easOtic is Virbac's treatment for otitis externa. It features a 1ml airless pump for precise measurement and an award-winning bottle design to aid compliance by ensuring easy and accurate application.
Epi-Otic is Virbac's antibacterial and antifungal ear cleaner for use in routine cleaning. It is pH neutral and contains sodium docusate, which dries the ear canal after application.
Practices making a qualifying purchase of both products will receive the Stain Kit, comprising the three staining solutions and three Coplin jars, free of charge.
For further information, contact your Virbac Territory Manager.
Hill’s Nurse Roadshows return in May with a 4 venue tour of the southern region. The theme is weight management and mobility and the organisers promise fun-filled, fact-packed events.
The evenings will address a broad ranging syllabus that includes setting up a weight management clinic using the latest dietary innovations alongside sessions on how to effectively promote it to your clients. It also will explain how to develop an individual exercise plan for both overweight but mobile animals, and for those overweight pets with mobility impairment.
Guest speakers include vet Lowri Davies who runs her own sports medicine and rehabilitation veterinary clinic in Swansea and is a holder of Certificates in both Veterinary Acupuncture and Canine Rehabilitation and Julie Corey Dip AVN (Med) Cert AAB MBIPDT (Adv) who qualified as a veterinary nurse in 1994 and has a Certificate in Applied Animal Behaviour as well as an Advanced Grade from the British Institute of Professional Dog Trainers (BIPDT).
The roadshows are being held at Milton Keynes on 12th of May, Tunbridge Wells on 13th of May, Exeter on 14th of May and Cheltenham on 15th of May. All the roadshow events run from 7.00 pm for an 8pm start and include a buffet meal and refreshments.
To book a free place at any of the roadshows including the practice based event in Cardiff call Jane Quail, Education Coordinator at Hill’s on 01923 814454.
The traditional approach is to use anatomical knowledge to inject pain relief in the area of the nerves to be blocked.
Liz is leading a move away from this approach to a more precise method which uses ultrasound guidance to visualise the nerves, allowing the local anaesthetic to be placed directly around the nerve itself.
For some nerve blocks, it is possible to block just the sensory branches of nerves, which means pets can walk better immediately after surgery while not feeling any pain.
Liz, a past president of the Association of Veterinary Anaesthetists, said: “Local analgesia is now at the forefront of our post-operative care and reliably improves the quality of a pet’s recovery and reduces the need for opioid pain relief, which can cause side effects.
“We’re using the latest techniques to deliver the nerve-blocking anaesthetics to exactly where they’re needed.
“For many of the nerve blocks, the use of ultrasound guidance allows more precise delivery and a complete blockade of the sensory nerves, which is why, here at Paragon, we’ve invested in state-of-the art ultrasound machine designed specifically for superficial and deep nerve blocks.
“This means we can provide more effective immediate post-operative analgesia for our patients and minimise the need for further pain killers.
“The nerves can be directly visualised and local anaesthetic directly placed around the nerve bundles.”
Liz is keen to highlight the advantages of the increased use of local anaesthesia in the treatment of animals. She added: “We’re hoping we’ll soon be able to publish some clinical research on the use of some of the blocking techniques used to demonstrate our clinical impression of their effectiveness in patient management.”
The new app has been specifically developed for CVS, is unique to the group, and is owned by the company.
It is powered by LocumBell technology.
When registering on the app, locums can input their work preferences - including their skills, desired travel radius and preferred shift times - so that they are only served up shift advertisements relevant to them.
Users can also set up notifications for upcoming jobs.
The app then allows locums to set minimum shift rates, submit the rate they would like to receive for a shift and negotiate their fees directly with a practice.
Shifts can be then be booked or cancelled on the app at the touch of a button.
All upcoming booked shifts appear on the users’ calendar.
Once a shift has been completed, locums can submit the invoice for their work using the app.
The app allows locums to see every CVS practice invoice and its status, which CVS says will allow queries to be resolved quicker and payments issued faster.
The app is being rolled out to all of CVS's practices from this August.
Amy Hughes, Head of Recruitment at CVS, said: “Locum administration can be time-consuming – as locums first have to identify work, liaise with a practice and our central support team, to negotiate and book a shift, then complete all invoice paperwork.
"We wanted to remove that pain and make it easier for locums to work with us.
The app is available for Apple devices on the App Store and for Android devices on the Play Store.
For any technical difficulties or assistance, contact: support@locumbell.com or call 0161 556 7685.
Invicta Animal Health has launched a new identification service for ChroMyco Duo dermatophyte kits in partnership with Axiom Veterinary Laboratories.
Veterinary practices can now send positive ChroMyco plates to Axiom and receive a species identification report for the specially discounted price of £8.00.
Rob Watkins, Managing Director of Invicta Animal Health said: "We are delighted to launch this service in response to customer feedback. This enables practices to gain a positive dermatophyte diagnosis in as little as three to six days so that treatment can be commenced promptly. Then, by sending the plate to Axiom, the actual species can be subsequently identified.
Axiom, with its innovative microbiology department and dedication to quality combined with its reliable network of courier services and postal processing systems are the ideal laboratory to provide this service".
Submission forms are available free of charge from Invicta Animal Health 01403 791313. ChroMyco Duo dermatophyte test kits are available from wholesalers and priced at £25.00 for 5 kits.
Those who pay their fees after 30 April 2017 will be charged an extra £35 to renew their registration while those who have not paid by 31 May 2017 will be removed from the Register.
You will also need to confirm your registration details, confirm you've met the RCVS requirement for continuing professional development of 105 hours over a three-year rolling period and disclose any new or previously undisclosed convictions, cautions or adverse findings.
The annual renewal can be completed by logging into the ‘My Account’ area of the RCVS website (www.rcvs.org.uk/login). For those members who do not have a valid email address, or have requested a hard copy of the renewal form, a form has been sent by post.
Any veterinary surgeons who have not received their annual renewal form or security details for the ‘My Account’ area by 7 March should contact the RCVS Registration Department on 020 7202 0707 or registration@rcvs.org.uk as soon as possible.
Those with queries about paying the annual renewal fee should contact the RCVS Finance Team on 020 7202 0723 or finance@rcvs.org.uk
Norbrook Laboratories has launched Cefimam DC intramammary ointment, a new dry cow preparation containing the 4th generation cephalosporin, cefquinome.
The company has also released a Polish language version of its Best Practice Guide for On-Farm Mastitis Control, in response to demand from producers with non-English speaking farm-hands.
Norbrook vet Chris Geddes said: "I believe this is the first time that such a guide has been produced to cater for farm-hands of a different nationality working within the UK. Good mastitis management starts with good education; giving everyone on the farm the same opportunity for learning the best techniques for prevention means that we help minimise incidences of mastitis, which costs the dairy industry millions of pounds in lost revenue every year.
"This prevention includes a thorough and consistent approach to dry cow management. The early drying off period is often a risky time, when pre-existing subclinical infections can bed-in. The cow is also at increased risk of gaining new infections due to lack of udder hygiene procedures that would normally occur at milking, and weakened immunity as she approaches calving. Our new cefquinome preparation is a valuable addition to have in the treatment armoury for dry cow management. It has broad-spectrum activity and high cellular penetration to help tackle hard-to-manage cases with the aim of returning to maximum productivity by the start of the milking season."
Cefimam DC will be available at all veterinary wholesalers in packs of 24x and 120x 8g intramammary tubes. Vets can obtain both English and Polish versions of the Best Practice Guide for On-Farm Mastitis Control from Territory Managers.
For further information or copies of the Best Practice Guide for On-Farm Mastitis Control in English or Polish, contact your Territory Manager or call Norbrook GB head office on 01536 741 147.
The BSAVA has released the final figures showing that 6,331 veterinary surgeons, nurses, practice managers and students attended the event, up from 6,178 in 2013.
Outgoing BSAVA President Professor Michael Day was delighted that so many attended. He said: "What continues to set BSAVA Congress apart is simply 'quality'. The quality of the faultless organisation, the quality of the scientific content, and the quality of our exhibition and incomparable social programme."
A few other numbers from Congress this year included:
Sunday saw the inauguration of the new BSAVA President Katie McConnell. She said: "Like so many previous presidents, I look back on my early volunteering days with deep affection but it would have been a great surprise to my earlier self to be told that one day I would be the BSAVA President.
"During my presidential year I would like to meet as many BSAVA members as I can, hopefully in their own regions. I plan to travel to regional BSAVA continuing education meetings, not to stand up and lecture but to listen to individual members and find out what the BSAVA means to them. The BSAVA is run by members for members and the only way to shape its work is to become engaged with it."
ECC vet Shailen Jasani has launched a crowdfunding campaign to raise funds for further development of his pet bereavement website, www.theralphsite.com
The Ralph Site is a non-profit pet bereavement support online resource and Facebook community which Shailen set up in 2011 after the loss of his cat Ralph.
Shailen says that over the past three years, the site has proved to be a much needed resource, with many pet carers benefiting from what it offers and a growing number of practices referring their bereaved clients to the site for information and support, and a sympathetic and empathetic virtual ear. So far, the site has had approximately 60,000 visitors and the Facebook community now stands at an impressive 34,000 Likes.
Shailen manages the site by himself and has has also personally funded all of the expenses to date including design, development, on-going management and promotion costs, to the tune of £30,000.
However, he says he now needs further funds to make the site work properly on smartphones and tablets, improve the memorial section and promote it more widely to pet owners, for which he is turning to crowdfunding and hoping that members of the profession will support what he is doing, both with contributions and by helping spread the word amongst family, colleagues and clients.
Shailen said: "The issue of pet bereavement and the impact of pet loss on their carers is a serious one which is slowly but surely gaining increasing recognition. A resource such as the Ralph Site is invaluable for practices to be able to link and refer clients to. I very much hope colleagues will get behind my campaign."
To find out more about the campaign, visit: http://igg.me/at/theralphsite/x
Apparently, anal gland impaction is the fifth most common reason for owners to take their dog to the vets1, and of course manual expression of impacted anal glands is unpleasant for everyone.
It also doesn’t address the underlying causes, such as poor stool consistency.
ProGlan contains pumpkin seeds and apple pectin, both sources of fibre to bulk out stools and increase faecal mass.
The product also contains Bacillus velezensisi (DSM 15544), a probiotic registered for use in dogs.
Animalcare points to research which demonstrates that lactobacilli help support a desirable gastrointestinal microbiome, aiding digestion and improving stool consistency2.
Lastly, the product contains a combination of Echinacea, vitamin C and vitamin E, which Animalcare says support a healthy immune and inflammatory response.
ProGlan is available in packs of 30 chews.
For further information or for orders, contact your local Animalcare territory manager or email info@animalcare.co.uk.
References
A research project funded by The Horse Trust has made important discoveries about how two peptides regulate the inflammatory response in horses. This knowledge could help with the development of improved anti-inflammatory drugs, which are used to treat a wide range of conditions in horses.
The research project was led by Professor Fiona Cunningham at the Royal Veterinary College in Hertfordshire and Dr Karen Rickards at the Donkey Sanctuary in Sidmouth, assisted by Dr Andrew Brooks at the RVC, and by Dr Kirstie Pickles, now at the Royal (Dick) School of Veterinary Studies in Edinburgh.
Inflammation is associated with a wide range of equine diseases, including recurrent airway obstruction, laminitis and sweet itch. Anti-inflammatory drugs, such as glucocorticosteroids, mainly work by blocking the formation and/or actions of compounds produced in the horse's body that cause inflammatory responses. However, these drugs are not always effective and can have unwanted side effects.
This research, funded by The Horse Trust, aimed to find out more about two naturally-occurring peptides - chains of amino acids that are shorter than proteins - known as annexin-1 and CXCL8. Both have been shown to affect the inflammatory response but little research has been done on their effects in horses. In the long term, knowing more about these compounds could help in the development of new anti-inflammatory drugs with fewer side effects.
During inflammation, neutrophils (a type of white blood cell) stick to the cells lining blood vessels and migrate into inflamed tissue, where they ingest and break down harmful agents. Using techniques that mimic these events, CXCL8 was found to cause adherence and migration of horse neutrophils. However, when it was used in combination with another pro-inflammatory substance, neutrophil migration and adherence were markedly decreased. This suggests that attempts to reduce inflammation by blocking the actions of CXCL8 might not be as beneficial as had been thought.
At the start of the project, the researchers had no information about horse annexin-1, other than its gene sequence, so their first step was to develop a method to detect the peptide in white blood cells. They established that it was present and, as horse annexin-1 has not yet been synthesised, they used a synthetic peptide derived from annexin-1, Ac2-26, to look at the effects on horse neutrophils.
They found that Ac2-26 decreased neutrophil adherence and migration in response to other pro-inflammatory compounds, although at high concentrations the peptide itself caused some cell activation, thereby increasing inflammation. They also found that dexamethasone (a glucocorticosteroid) increased the levels of annexin-1 in cells, indicating that, as in humans, this class of drugs is likely to act in part through the formation of annexin-1.
These findings suggest that the use of compounds which mimic the actions of annexin-1 may have limitations as anti-inflammatory drugs. As glucocorticosteroids partly work by forming annexin-1, further research is needed in order to find out how annexin-1 will act in the horse's body and establish how its formation contributes to the beneficial effects of these drugs.
Professor Cunningham said: "This Horse Trust-funded research has resulted in some very interesting findings about how inflammatory cells are regulated in horses. The receptors that annexin-1 and CXCL8 act upon could be targets for new equine inflammatory drugs, but more research is needed first to fully understand their actions and how they produce these effects."
The team's research has been accepted for publication by the journal Veterinary Immunology & Immunopathology.
Freelance Surgical Ltd has announced a limited offer under which it will supply all of the instrumentation and capital equipment required for a veterinary practice to set up a new laparoscopy service, for £10,000 +VAT
The company says it has seen a substantial number of requests for laparoscopic instrumentation and capital devices in recent months. James Towler, Veterinary Director said: "Keyhole surgery is becoming increasingly popular within the veterinary field and the driving force is the client. They are now more informed of the benefits of what this type of surgery can offer. Our goal is to be able to provide veterinarians with an affordable package that will allow them to cater to client request s rather than referring the patient to their competitors."
Freelance Surgical says using laparoscopy has proven for many to generate a new revenue stream as well as offering improved patient outcomes. According to the company, a practice performing 6 bitch spays a week can generate over £50,000 in just 3 years*
For more information contact Freelance Surgical on 0845 050 4147or visit: www.freelance-veterinary.co.uk