The company points to a survey of 1000 dog owners it conducted in July which found that 77% would put many of the top ten signs of Cushing's down to ‘old age’.
According to research carried out by CM research in July 2018, for every 100 cases of Cushing’s syndrome treated, a further 57 are suspected but not diagnosed.
The ‘Prime Suspects’ campaign will encourage dog owners to become a ‘Cushing’s Detective’ and look out for signs in their dogs.
To help, the company has developed a series of characters to illustrate the signs of Cushings: Panting Patsy, Leaky Larry, Lazy Lynn, Greedy Gus and Little Patch.
A nationwide pet-focused multimedia campaign will support the ‘Prime Suspects’ initiative and will include TV and print advertising, online banners, pay per click advertising and social media to engage owners and encourage them to seek advice from their vet if they suspect Cushing’s in their dog.
Dechra has also launched Cushing’s Connect, a digital platform single resource hub to help vets keep up to date with current best practice in managing Cushing’s.
The hub has information and tools to enhance diagnostic protocols, advice and literature covering pathophysiology, diagnosis and ongoing case management including treatment protocols and monitoring schedules, and interactive guides and videos by top veterinary specialists.
There's also a client communication toolkit with owner-focused resources to encourage dog owners to spot the signs and seek help from their vet.
https://www.dechra.co.uk/cushings-connect
Independent research carried out by CM Research amongst practising companion animal veterinary surgeons has placed VetSurgeon.org in the top 5 veterinary media publications, and the leading online destination by a considerable margin.
As part of the research, 300 vets were asked which media publications they followed. Unprompted, 24% answered VetSurgeon.org, placing the site in 5th place alongside such venerable titles as Veterinary Times, Veterinary Record and The Journal of Small Animal Practice.
Carlos Michelsen, Managing Director of CM Research said: “The answer to this question was unprompted, so the leading titles will likely have benefited from the greater brand awareness that comes from having their magazines delivered to the practice, and the fact that they’ve been in existence for so much longer than VetSurgeon.org. That makes this an even more remarkable achievement for the site."
In terms of online media used by veterinary surgeons, VetSurgeon.org was the clear winner, by a number of lengths. Where 24% of vets said they followed VetSurgeon.org, only 5% followed the second placed website published by Vet Times. Indeed the percentage of vets reported as following VetSurgeon.org was very nearly the same as the percentage that visited all the other veterinary websites combined.
Arlo Guthrie, Publishing Editor of VetSurgeon.org said: “I’m over the moon. When I set up VetSurgeon.org 8 years ago, people said ‘it’ll never work’. So to be sitting here talked about in the same breath as a title like the Veterinary Record, which has been around for 125 years, fills me with a huge sense of pride.
“If I’m allowed my little ‘Oscar’ moment, I would like to thank the members of VetSurgeon.org, without whom none of this would have been possible. I know, it’s a dreadful cliché, but the success of VetSurgeon.org is entirely down to its members, both those who actively participate in the forums and those who just come to read content. I am enormously grateful to you all.
“I’m also hugely excited about the future. We’ve got so much in the pipeline - all designed to further help the sharing of knowledge and experience within the profession. Stay tuned!"
Further investigation revealed that the products in question: AVA Mature Cat Chicken 2kg, AVA Mature Cat Chicken 4kg, AVA Senior Cat Chicken 2kg and AVA Adult Cat Neutered Indoor 1.5kg, all had insufficient levels of thiamine (vitamin B1), which caused the cats to exhibit symptoms of sudden collapse, fitting, widespread twitching and general unsteadiness.
Talking to the BBC, Pets at Home spokesperson Brian Hudspith said it was important to alert veterinary surgeons as well as customers because thiamine deficient cats would usually present with quite different symptoms, including stiff limbs and the head falling onto the sternum.
He said: "Rather than the more typical cervical ventroflexion (head falling onto the chest) associated with thiamine deficiency, in the three cases we saw the predominant clinical signs included sudden collapse, fitting, widespread twitching and general unsteadiness on their legs, which began suddenly after 4-6 weeks of being on the diet."
Pet owners who have bought the products are being advised by the company to dispose of the contents and return the packaging to any Pets at Home store for a full refund. Owners who think their cat is demonstrating any of the symptoms are being advised to seek immediate veterinary advice, and to contact the company's customer advisors on 0800 328 4204.
IMPORTANT UPDATEDavies Veterinary Specialists has published advice and support for veterinary professionals and pet owners concerning the diagnosis and treatment of thiamine deficiency in cats, here.
According to the RVC, recent studies estimate dental disease affects up to 18% of the UK's rabbits and breeds with lop ears and short skulls (brachycephaly) have long been suspected of being more at risk.
To investigate whether there is any truth to that suspicion, a team of RVC researchers led by Maria Jackson RVN, Research Assistant in Rabbit Health and Welfare, and Dr Charlotte Burn, Associate Professor in Animal Welfare and Behaviour Science, set out to explore whether these physical features are linked to dental problems.
The study involved visual dental checks of 435 volunteered pedigree rabbits from 49 breeds at British Rabbit Council shows and breeders’ studs across the UK.
The researchers assessed tooth and mouth health using an otoscope, while also recording ear type, head shape (on a purpose-made visual scale), body size, age and sex.
The findings revealed that:
In conclusion, the study concluded that diet, environment and regular dental checks might be more important in the development of dental disease.
The researchers also concluded that any breeding decisions should be based on veterinary assessment of dental health, including otoscope or radiography examinations rather than relying solely on visual inspection of the teeth or a rabbit’s conformation.
Maria said: “Our findings add to the evidence that suggests lop ears and a brachycephalic head shape are less important in the development of dental issues in rabbits than was once thought.
"It’s clear that all rabbits, not just those with a non-wild conformation, can be affected by dental problems.
“The importance of feeding good-quality hay or grass and supplementing the diet with extruded pellets, not muesli, cannot be overstated, as diet may well be more important than conformation in the development of dental disease.
"Likewise, providing regular veterinary dental check-ups to rabbits is crucial to facilitate early dental disease detection and give case-specific dietary and treatment recommendations to slow disease progression and support the welfare of rabbits.”
Reference
Photo: depositphotos.com
Alison has been an active member of the BSAVA since graduating from the University of Glasgow Veterinary School in 1991.
She works in small animal practice and has completed a residency in feline medicine at Liverpool University’s School of Veterinary Science, as well as a PhD in canine Bordetella bronchiseptica.
She has also spent two years working in industry.
Sheldon will stay on to support the BSAVA as Senior Vice President.
Alison says her priorities for her time in office are to develop more innovative materials across the Association's Education, Congress, and Publications arms, to beef up the digital offering, and to focus on mental heath and wellbeing in the profession.
Alison said: "I’ve been a passionate member of the BSAVA throughout my career and a volunteer for almost as long.
"As a working vet, I know first-hand the value of being part of a professional community: the importance of shared values, educational opportunities, and support shouldn’t be underestimated.
"We must remain focussed on the day-to-day challenges veterinary teams face, respond appropriately and at pace, and continue to explore new and effective ways to support our members.”
The company developed the new version with input from veterinary surgeons, nurses and APPCC (Association of Private Pet Cemeteries and Crematoria) members.
Their recommendations, which have now been incorporated into the new design, include:
The new Pet Porters will be available from leading veterinary wholesalers from May.
However, MDC says that if you want to pre-order before the end of April, an introductory 10% discount is available on its website www.mdcexports.co.uk
Elanco Animal Health has announced the launch of Osurnia, a new treatment which it says will drive compliance when treating canine otitis externa infections.
According to the company, compliance with daily ear drops has been shown to be poor, with up to 80% of owners administering the incorrect dose to their pet. The most common reason for a lack of compliance is the difficultly in applying the drops1.
Elanco says that Osurnia has the potential to improve compliance in treating otitis externa significantly, because unlike other medications which require 5-28 doses during the course of treatment2, Osurnia only needs two-doses given a week apart.
Osurnia contains a gel formulation of three active ingredients including the antibiotic florfenicol, which is new to companion animal treatment in the UK, terbinafine, which inhibits the growth of yeast as demonstrated for Malassezia spp., and the glucocorticosteroid, betamethasone acetate, to help relieve discomfort.
Osurnia is administered in a pre-measured, single-dose tube designed to ensure the right dose every time. It has a flexible, soft tip designed to make treatment with Osurnia a comfortable experience for the dog. The gel formulation squeezes out of the tube and spreads through the ear, adhering inside the ear canal for long-lasting action. The dose is the same for any dog, regardless of size and weight.
Alice Laurens, DVM MRCVS, dermatology marketing manager at Elanco Animal Health said: “Otitis externa is a common challenge for both vets and clients, with ear infections among the ten most frequent reasons for dogs to be presented with vets, affecting up to 20% of dogs3.
“Osurnia is an innovative, effective treatment that is administered in just two doses ensuring it is much more convenient for pet owners thereby increasing the likelihood that they will complete the entire treatment schedule leading to more comfortable dogs and peace of mind for owners.”
Elanco has produced a client leaflet on treating otitis externa with Osurnia. For further information, or to order client leaflets, please contact your local Elanco Animal Health Territory Manager or email elancoCAH.uk@elanco.com.
References
A Lincolnshire couple desperate to find an alternative to Elizabethan veterinary collars, after their dog Tess suffered a traumatic experience, have invented a new range of wound coverings called Cozi-fit.
According to Terri and Dave Ward from Skellingthorpe near Lincoln, who designed the new product, Cozi-fit is the clear alternative to Elizabethan or Buster collars. It comes in five different sizes, and the couple say that Cozi-fit is already going down well with vets and pet owners alike.
The idea for the Cozi-fit came about after the Ward's dog Tess had a hysterectomy. Dave said: "The hysterectomy was stressful enough, but Tess then had to wear a collar to stop her licking the wound. We also had to isolate her from our other dogs and she quickly became depressed and stopped eating.
"We were so worried about her that I decided to try and make a replacement using a pillowcase which we attached to her collar and fastened round her torso and hindquarters. As the wound was covered she could be around our other dogs and her movement wasn't restricted in any way.
"I was so delighted with the result that I decided to refine my design and took it to our local vet to get his opinion and it kind of grew from there. The wound coverings now come in five different sizes to suit all dogs and cats and are made from durable cotton fabric.
"We now supply over 30 veterinary surgeries including a number of Companion Care vet surgeries as well as the RSPCA and are currently in negotiation with retailers up and down the country."
Peter Munro from Whitegates Veterinary Practice said he was impressed when Terri first came to him with her initial idea: "Cozi-fit wound covers have proved to be a great benefit in protecting abdominal and castration wounds from self-trauma, especially where collars are not well tolerated and we've had some really positive feedback from our clients."
Although the product has been well received since coming on the market Dave says there are still thousands of vets, breeders and pet owners who are unaware of Cozi-fit.
"Vets perform over three million operations every year in the UK, many of which will be neuters, caesarean sections or other types of abdominal surgery, and Cozi-fit is ideal for these types of procedures.
"It is easy to fit, allows free and natural movement at all times and is a more pleasant experience for both the animal and their owner."
For more information about Cozi-fit please visit http://www.cozi-fit.com/.
Virbac Animal Health has announced that registrations on BackHome BioTec, the company's microchip identification service, were moved to the Petlog Database with effect from Monday 12 September 2011.
Virbac says it moved to the UK's largest independent microchip registration database in order to offer an enhanced level of service and support, both to veterinary staff and pet owners.
Practices using the BackHome BioTec system are being asked to log onto www.virbacbackhome.co.uk to create a new account.
Gillian Brown, Product Manager for BackHome at Virbac, said: "BackHome has established itself as a popular, cost-effective and easy to use microchipping system. We believe that in appointing Petlog to manage our registrations we will now be offering a 'best of breed' service for veterinary staff and pet owners.
"We're extremely grateful to Celia Walsom, Petlog Executive, and her team. They have demonstrated unfailing energy, expertise and total dedication to ensuring this move has run smoothly and effectively for all our customers. I am confident that they will benefit from Petlog's commitment to provide a comprehensive identification service which is easy, convenient and secure to use.
"All our existing customers need to do is go to the new website (www.virbacbackhome.co.uk/) and set up an account - it's a simple and quick process. We'll also be providing a range of promotional materials to help them communicate the change to their own clients."
Petlog is owned and managed by the Kennel Club. Virbac says it is fully data compliant and defers income to ensure it can honour its lifetime promise to pet owners. Its Lost and Found helpline is available 24/7, 365 days a year and it is also a founder member of the European Pet Network.
Further information on BackHome BioTec is available on the new website, which also contains a direct link to Petlog.
For further information about BackHome BioTec, please contact your Virbac Territory Manager or call the company on 01359 243243.
The research, carried out by the Royal Veterinary College’s (RVC) VetCompass programme, involved analysing data from 333,910 bitches who presented at veterinary practices participating in the programme between 2014 and 2017.
The study also indicated that the females of certain breeds are more prone to UI than others, with Hungarian Vizslas, Doberman, Weimaraners and Boxers most at risk.
UI affects around 3% of bitches in primary veterinary care in England.
The researchers say that a connection between neutering and UI in bitches has long been suspected but this study provides stronger evidence on the extent of the relationship.
The data also showed that age and bodyweight are major contributory factors to bitches developing UI as well as neutering and breed. Other key findings include:
Bitches over nine years old are 1.7 times more likely to develop UI compared to those younger than three years.
Bitches weighing over 10kg are 1.9 more likely to develop UI than those weighing less than 10kg, while bitches over 30kg are three times more likely.
Camilla Pegram, VetCompass epidemiologist and lead researcher on the study, said: "First opinion vets discuss and perform neuters on a daily basis but, until now, evidence on the link between neutering and urinary incontinence has been tenuous.
"This study provides stronger evidence of an important association between neutering and urinary incontinence. The decision to neuter a bitch is based on many factors, not just incontinence risk alone. However, these results suggest that the component of the decision driven by urinary incontinence could be emphasised for the high-risk breeds and bitches of larger bodyweight.”
It is hoped that the results will aid owners and vets in making evidence-based decisions when it comes to neutering female dogs.
Merial is offering four free tubes of Eqvalan Duo to practices that buy 20 tubes in February and March. In addition, to further boost the targeted worming message, Merial will supply 20 free worm egg count vouchers worth £10 each.
Eqvalan Product Manager Claire Edmunds said: "Last year's campaign was so well received by both practices and clients that we have decided to run it again and are hoping for even better results!
"The personalised online planner, worm egg count offer and new eye-catching point of sale all help you to engage your clients in a targeted worming strategy.
For those practices with their own, in-house worm egg count testing facilities, Merial is also offering promotional support to help encourage increased uptake and client buy-in. The campaign forms part of Merial's promotion and education strategy for 2011, which includes extensive VN SQP CPD training opportunities.
To find out more contact your local Area Manager or call the Merial Customer Support Centre on 0845 601 4236
The Veterinary Benevolent Fund has launched a short film about a veterinary surgeon's experience of severe depression and her inspiring recovery.
The charity says it hopes the film, published on the Vetlife website today, will encourage the veterinary profession to talk more openly about stress and depression in the workplace and will motivate veterinary employers to adopt best practice in supporting their staff's mental health.
Nick Short, the VBF Director responsible for the development of the Vetlife website, said: "We are so grateful to the veterinary surgeon concerned for having the courage to share her story and for her insights into what could be done to make recovery easier for other vets. We were delighted to hear that she felt she was treated well and got the help she needed from the Veterinary Benevolent Fund and the Veterinary Surgeons' Health Support Programme.
"Recent press reports have estimated that the cost to the UK economy of stress, depression and suicide is £26 billion per year. We know that the profession has a high incidence of these problems, so it follows that depressive illness must have an alarming economic effect on it. This means it is essential to invest in improving awareness and support.
"The VBF wants to produce more web videos on issues that veterinary surgeons, students or nurses commonly encounter such as debt, addiction, professional conduct or employment problems. However, we need to secure additional sponsorship in order to fund this work - each 5 minute video will cost about £2,500 to produce. If you or your organization would be interested in supporting this work, please contact the VBF office at 7 Mansfield Street, London W1G 9NQ, telephone 020 7908 6385 or email info@vetlife.org.uk. Donations can also be made online at www.justgiving.com/VBF"
Rory O'Connor, National Co-ordinator at the Veterinary Surgeons' Health Support Programme said: "Many of us will have mental health problems at some point in our lives but most can make a full return to work with the right support. As highlighted in the film, it is really helpful if employers are willing to explore adjustments to working conditions or to the working environment such as flexible working hours or changes to working responsibilities. I am always available to help both employers and employees with these kinds of discussions and we are currently developing content on mental health support in the workplace for the Vetlife website. All advice is completely confidential."
The film was made by John Somers and Ben Sheriff at the University of Exeter using an actress to speak the words of the veterinary surgeon.
Sue, an RCVS and European Specialist in Veterinary Dermatalogy and Senior Vice President of the European Society of Dermatology, says the failure to prioritise pain relief is having a "profound effect on the quality of life of both dogs and clients."
Sue is urging vets to think about the impact that pain has on both the dog and owner in cases of OE: "Otitis externa is painful, it’s debilitating, and the degree of discomfort is often underestimated by both the veterinary surgeon and by the client."
Sue also says vets should not underestimate the owner’s concern about pain in their dog. Owners recognise the clinical signs associated with the pain of OE and determine treatment success by their dog recovering from these distressing symptoms.
To help manage the pain associated with OE, Sue recommends a multi-modal approach: "In addition to systemic pain relief, which is really important, a potent topical steroid is really useful to reduce the inflammation inside that dog’s ear, and make it much more comfortable."
Sue also highlights OE treatments which are able to coat the ear canal and stay there long enough to treat the pathogens and provide sustained pain relief: "When you put it into the ear, Osurnia Gel coats the lining of the external ear canal which gives prolonged contact with the lining of the canal to help treat the pathogens inside that dog’s ear."
Elanco says that despite Osurnia entering the market two years ago, some vets are still saving it for difficult cases. Sue said: "Too many vets use this [Osurnia] as a second-line drug and it should be used as a first-line product on the first occasion the dog comes through the door."
To watch the full series of videos and to find out more from Sue Paterson on treating otitis externa in dogs, visit: www.Osurnia.co.uk
The case against Jose Ignacio Messa MRCVS related to two heads of charge against him.
The first charge was that, on 13th September 2015, Mr Messa failed to provide adequate and appropriate care to Barney, a border collie. The second charge was that on 14th September 2015 Mr Messa failed to ensure adequate and appropriate on-going care for Barney after his examination of him, including failing to take sufficient steps to ensure that Barney was referred urgently to the care of a referral practice and failing to ensure there were adequate arrangements in place for his ongoing care.
Barney was presented to the Basingstoke practice where Mr Messa was employed having suffered a severe 'stick injury' to his jaw on 12th September.
The Committee heard that, on 13th September, Mr Messa re-examined Barney, administered medication and then discharged him to be cared for at home by his owners. During the examination the owners alerted Mr Messa to the condition of the skin on Barney’s neck, but the Committee heard Mr Messa had felt the area and reassured them it was not something to be concerned about.
The Committee heard that at some point on 13th September, after he was discharged, Barney developed a foetid smell from his mouth caused by an infection and the next day his owners went back to the practice because Barney’s condition had deteriorated – he was unable to walk and had laboured breathing.
On 14th September Mr Messa admitted and sedated Barney and examined him again, noting a hole in the side of his throat that was infected. He recommended referring Barney to a referral practice for further treatment, which was agreed by his owners.
The Committee heard that the referral practice was contacted by a veterinary nurse at the practice and that an appointment for 9am on 15th September 2015 was booked directly with the owner. It also heard that, during his time at Mr Messa’s practice, Barney did not receive intravenous fluids or any further antibiotics.
Barney’s owners said they met with Mr Messa again at around 5pm on 14th September when they came to collect Barney, this was disputed by Mr Messa, and the Committee were not satisfied so as to be sure that it had been Mr Messa who had met the owners and discharged Barney although the Committee found that all the witnesses had been honest and reliable.
Barney was admitted to the referral practice on 15th September but, as a result of sepsis, he suffered a cardiac arrest and died at 10.30pm.
In respect of the first charge the Committee concluded that, on 13th September, Mr Messa made only a rudimentary examination of Barney, and the absence of such basic clinical examination of the temperature, the respiration rate and the pulse of Barney was a failure on the part of Mr Messa and that, furthermore, he did not choose the best course of antibiotic treatment for the wound and infection.
In respect of the second charge Mr Messa admitted that he did not provide fluid therapy to Barney on 14th September before he was discharged.
With reference to the remaining aspects of the charge the Committee took into account the Code of Professional Conduct, particularly in respect of the need for veterinary surgeons to refer cases responsibly and the Code’s supporting guidance on referrals.
The Committee determined that, having delegated the arrangements of the referral to a veterinary nurse, Mr Messa made no attempts to follow up and ensure it was a same-day appointment when this would have better suited the severity of Barney’s condition. The Committee found that he was unaware of Barney’s location or of the time of the appointment and did not make provision for antibiotic or fluid therapy.
Having found the majority of the charges against Mr Messa proven, the Committee then considered whether this amounted to serious professional misconduct.
Disciplinary Committee member Stuart Drummond, who was chairing the Committee and speaking on its behalf, said: "In the light of the facts found proved and considering that disgraceful conduct in a professional respect is that which is conduct falling far below that expected of a veterinary surgeon, the Committee had concluded that the heads of charge, when taken individually, or collectively, do fall below the standard expected.
"However, as a matter of judgement, the Committee did not conclude that Mr Messa’s conduct fell far below the requisite standard and therefore did not amount of disgraceful conduct in a professional respect.
"Whilst the Committee did not find Mr Messa’s actions fell far below the requisite standard, there were concerns expressed about several aspects of this case. There were a number of missed opportunities which occurred; in particular the Committee notes the failure of the care plan and to take adequate steps to ensure that the referral process has been timeously effected."
Chair of the Standards Committee, Dr Melissa Donald, said: “We were very aware of the likelihood that both practice staff and clients will increasingly have to isolate over the coming weeks due to direct infection or positive contacts, particularly with the rise in cases amongst school children.
“Added to this, we know there are already workforce pressures across the profession, which will be exacerbated by reduced staffing levels over the Christmas and New Year period.
“We therefore felt it was appropriate to reintroduce these temporary remote prescribing measures at this time to help relieve pressure on practising professionals, and to provide them with the means to continue to look after the health and welfare of their patients in all circumstances.”
As before, the temporary dispensation is subject to the specific guidance found in FAQ4 (www.rcvs.org.uk/covidfaq4), including that veterinary surgeons must be able provide a 24/7 follow-up service involving physical examination, for example where the animal does not improve, or suffers an adverse reaction, or deteriorates, subsequent to the remote prescription of medicines.
The Committee agreed that the position should be reviewed in February 2022 at its next meeting.
Agrimin has announced the launch of a new range of boluses for sheep and cattle that use 'eroding technology' to deliver a sustained supply of three trace elements for up to 180 days:
According to Agrimin, each bolus is designed to provide the full daily requirement of cobalt and selenium and the largest available daily supply of iodine to both cattle and sheep. The boluses do not contain any copper, an element known to cause issues in certain parts of the country, in closely managed dairy cows or in continental sheep breeds.
Each bolus is made up of two parts, held together by a soluble wrapper. After administration, the wrapper dissolves and the two halves remain in the reticulum where they erode and dissolve. This process delivers a continuous and regular supply of nutrients to the animal.
Agrimin's Dr Jamie Bennison said that the new range has been extensively trialled in New Zealand and at Glasgow Veterinary School: "Trials have confirmed a sustained release profile which ensures that iodine, selenium and cobalt levels are maintained throughout the active life of the bolus. In farm trials this has translated into higher levels of the elements in blood samples and improved animal productivity."
Treatment is one bolus per animal (48g for sheep; 160g for cattle) administered with an Agrimin bolus gun. One bolus is sufficient to meet the animal's full daily requirement for 180 days.
For more information about the 24•7 Iodine•Selenium•Cobalt range of cattle and sheep boluses, please visit http://www.agrimin.com/ or call 01652 688046.
Their study, which was published in the research journal PeerJ at the end of last year1, investigated the effects of insulin on equine hoof lamellar cells in the laboratory.
The researchers say that high levels of insulin have been known for some time to cause acute endocrine laminitis, seen when ponies and certain types of horses graze lush pasture or consume a starch- or sugar-rich diet, or when they develop Cushing’s syndrome.
Many ponies and horses at risk of the condition produce large spikes of insulin in their blood stream after consuming meals high in non-structural carbohydrates (in particular starch and simple sugars) which indicates that this could be the way in which they succumb to acute endocrine laminitis.
The mechanism by which insulin can cause effects in the foot leading to laminitis has been the subject of much debate in recent years.
Hormones like insulin must interact with a specific receptor on the surface of cells in order to produce their effects. What has confused researchers in the past is that there appear to be no insulin receptors on the hoof lamellar cells (these cells give the lamellar tissues their strength and changes to their growth or structure weaken the bonds and cause laminitis).
The researchers considered the close similarities between insulin and a growth factor hormone called insulin-like growth factor -1 (IGF-1). There are receptors for IGF-1 on the lamellar cells, and the researchers speculated that high concentrations of insulin might be able to cross-stimulate these cells by activating the IGF-1 receptors. To investigate this possibility PhD student Courtnay Baskerville, together with her supervisor Professor Simon Bailey, developed a method for culturing lamellar epithelial cells in the laboratory, and incubated them with increasing concentrations of insulin.
They found that high concentrations of insulin stimulated the cells to proliferate. Furthermore, this effect could be prevented using an antibody that specifically blocks only the IGF-1 receptor. Further downstream effects within the cells were also shown. The changes seemed to occur mainly at very high concentrations of insulin. Similar concentration levels can be seen in ponies and horses with insulin dysregulation linked to Equine Metabolic Syndrome, but are not commonly seen in normal horses that are considered to be at lower risk of laminitis.
Further work is now ongoing to determine exactly how these cellular changes induced by sustained high insulin concentrations might cause laminitis. However, it seems that targeting the IGF-1 receptor may be an option for developing new drugs to prevent and treat laminitis.
Professor Simon Bailey said: "The information gathered in this study provides the equine industry worldwide with valuable insights into the causes of the common and serious condition of laminitis. The research group would like to acknowledge the support of the Waltham Centre for Pet Nutrition, in particular the involvement of Professor Pat Harris.”
The practice has been leading research into the devastating disease since 2012 and has collated information on all confirmed cases across the country.
The disease, which originally appeared in the late 1980s, was first detected in the UK in 2012.
When it affects the kidneys, it has a 90% mortality rate.
The new site offers advice and information, including a live map of confirmed cases across the UK, for both vets and pet owners.
David Walker, American, RCVS and EBVS European specialist in small animal internal medicine, leads the team at Anderson Moores and is the UK’s foremost authority on the disease.
He said: “We have been at the forefront of research into CRGV for almost a decade now and have witnessed first-hand the often-devastating effects of the disease.
“In launching this new website, we aim to inform pet owners and colleagues in the veterinary industry about CRGV.
“We hope the confirmed case map will prove useful.
"Although an environmental trigger has not been definitively proven, the seasonality of the disease makes it eminently possible and the map allows everyone to see the location of confirmed cases.”
So far this year, Anderson Moores has recorded a total of 26 confirmed cases of CRGV.
This number comes on the back of 47 confirmed cases during 2020, 19 cases in 2019 and 18 in 2018.
277 cases have been confirmed since the disease was first recognised in the UK in 2012.
David said: “As we enter the winter months, we want to advise dog owners around the country to remain calm but vigilant and seek advice from their local vets if their dog develops an unexplained skin lesion(s), especially on the leg.
“Unfortunately, we find ourselves in the time of year when cases are most commonly identified – 92% of dogs with the disease are seen between November and May.
"This is understandably a concern for dog owners; however, the disease remains rare.
“If a dog is suspected to be suffering from CRGV, the best chance of recovery probably lies with early and intensive management which may be best provided at a specialist facility.
“Treatment primarily revolves around intensive management of the acute kidney injury and is sadly only successful in around 10% cent of cases.”
Visit https://www.alabama-rot.co.uk .
For the study, researchers from the RVC’s VetCompass Programme identified 2,105 hypothyroidism cases diagnosed amongst a study population of 905,553 UK dogs.
This revealed an annual frequency of one case in 400 dogs (0.23%) for the condition, with the most common breeds diagnosed being Standard Doberman Pinschers (x 17.02), Tibetan Terriers (x11.25), Boxers (x10.44) and Alaskan Malamutes (x 9.71).
The average age at first diagnosis was 7.65 years.
Other findings included:
Dr Rebecca Geddes, Lecturer in Small Animal Internal Medicine at the RVC Queen Mother Hospital for Animals and last author of the paper, said: “It is great to have this data from UK primary care practices, which will help highlight high risk breeds to veterinary surgeons so they can diagnose and treat affected dogs as early as possible. Hypothyroidism is usually straightforward to manage with medication that can greatly improve quality of life in affected dogs.”
As part of the scheme, Linnaeus offers one-to-one mentoring, professional and clinical skills development in primary care practices across the UK as part of the scheme.
The group, which now has more than 3,000 employees, delivers all clinical training in-house through its network of specialists, referral clinicians, certificate holders and primary care clinicians.
The 2021 programme applications will remain open until the end of May, unless all positions are filled sooner.
Chloe Roberts, clinical and educational development manager at Linnaeus, said: “This will be the fourth cohort to join our GDP and we’re looking forward to building on the successes we have enjoyed over the last three years.
“This has been a challenging year for obvious reasons, so it has been extremely heartening to see our new vets rise to that challenge and continue their professional journeys with our support.
“We’re excited to hear from the next intake of new vets and look forward to supporting them in their transition to clinical practice and recognise the additional challenges they faced joining the profession in the midst of a global pandemic.”
For more information, visit graduates.linnaeusgroup.co.uk or www.instagram.com/linnaeusgdp.
The new distribution service uses Invatech's Patient Medication Record (PMR) system, called Titan, which was accredited by the NHS a little over a year ago. Titan has now been developed further to support the company's Home Pharmacy service, and integrate with MWI.
The company says the new system offers practices a seamless workflow between prescribing, dispensing and logistics systems.
Tariq Muhammad, CEO of Invatech Health, said: "“The use of PMR systems for the veterinary market has been very light touch until now. Knowing that that we can bring the same level of efficiency and workflow to a new market presents an opportunity to support animal health in the same way that we do for human health."
Alan White, Commercial Director at MWI Animal Health, said: “The Covid pandemic has presented many challenges to veterinary professionals in the UK. Travel restrictions and social distancing measures make it difficult for animal owners to collect the medications and treatments they need from veterinary practices.”
“We are excited to be able to work with Invatech to provide an innovative solution to this problem, where vets can send the medications needed directly to their client. Working in partnership with veterinary practices and Invatech means we can move animal health forward together.”
For more information, visit: https://www.invatechhealth.com/
Buprecare is indicated for post-operative analgesia and the potentiation of the sedative effects of centrally-acting agents in dogs, as well as post-operative analgesia in cats.
It is presented in a 10 ml multi-use bottle.
Animalcare Product Manager Eleanor Workman Wright said: "Buprenorphine is a potent, high affinity, synthetic opioid.
"It plays a central role in many practice anaesthesia protocols so we are delighted to announce that it is back in stock."
For more information, contact your Animalcare Territory Manager or contact Animalcare’s head office on 01904 487687.
For the study, urinalysis results from 2,712 UK feline urine samples submitted and analysed by Axiom and Finn over a period of 14 months2 were reviewed.
Urine samples had to have been obtained by cystocentesis and signalment information recorded by their submitting vet3.
These samples did not have to come from cats presenting with FLUTD signs and the researchers therefore say that consideration should be given to a different (potentially even more increased) prevalence in cats presenting with LUT signs.
Bacterial urinary tract infections in cats with FLUTD are estimated to be present in around 8 – 19% of cases4.
However, FLUTD is one of the most common reasons for the use of antimicrobial drugs in veterinary medicine and is therefore an important condition to consider to minimise antimicrobial use and development of antimicrobial resistance5.
The study found that 15.7% of the samples had a positive culture, with E. coli (43.7%), other Enterobacterales (26.4%) and Enterococcus spp (14.9%) being the most common isolates identified.
Antimicrobial susceptibilities and resistance were also tested.
Notably, Enterococcus species were frequently found to be resistant to multiple antibiotics, and several other isolates demonstrated resistance to frequently used antibiotics.
The data showed Enterococcus spp. were much less susceptible to trimethoprim and sulfamethoxazole (TMPS) than have been previously documented (with 94% of isolates resistant).
Additionally, other Enterobacterales had resistance against cephalosporins and penicillins.
The authors say that data surrounding cephalosporin resistance is particularly notable and problematic; recent data has indeed shown that the cephalosporin cefovecin is a commonly prescribed antibiotic3 for cats presenting with lower urinary tract disease.
The authors also say that data in this study adds to the existing evidence that the use of cephalosporins such as cefovecin may be ineffective in many cases (intrinsic resistance of Enterococcus spp) and therefore should be avoided unless cystocentesis and signalment results support their use.
The inappropriate use of antibiotics for bacterial cystitis could not only be ineffective to manage bacterial cystitis in cats but promote further antimicrobial resistance.
Clarisse D’Août, lead author of the research and Internal Medicine Specialist at Lumbry Park Veterinary Specialists, said: “Even though feline lower urinary tract disease is one of the most common reasons for vets to prescribe antibiotics, the prevalence of bacterial strains in the urine of cats with this condition, and their resistance to commonly used antibiotics, had not been widely studied in the UK to date.
"So we hope that this study can add to the current evidence to making well-justified and practical recommendations in practices about which antibiotics to choose and those to avoid.
"We see this ongoing susceptibility testing as clinically important to avoid the development of further resistant bacteria.”
The book is described as giving comprehensive information to support the diagnosis and treatment of commonly seen pathologies of dogs and cats, such as haematology, immunology, diagnostic imaging, respiratory diseases, cardiovascular medicine, reproductive system disorders, gastrointestinal disorders, as well as hepatobiliary and exocrine pancreas disorders.
Each chapter has been authored by an internationally recognised expert in their field.
Improve says its books support delegates studying for its Postgraduate Certificate, but are also a useful reference source for other veterinary surgeons.
John Douglass, General Manager of Improve International, said: "Following the positive response to our first textbook, the Improve International Manual of Small Animal Surgery, we felt it was important to follow up with a small animal medicine equivalent. We’re therefore very happy to unveil volume one of the Improve International Manual of Clinical Small Animal Internal Medicine and look forward to the launch of the second volume later this year."
He added: "Our textbooks focus on the practical application of current veterinary knowledge, offering top tips and key advice throughout expressed in an engaging and highly visual format to ensure that they are perfect for those in need of a quick ‘look up’ in practice.”
The new books can be bought from www.improveinternational.com/uk/books, www.5mbooks.com or from booksellers worldwide. They are also available in Spanish with translations into additional languages planned.
The offer is timed to coincide with the expected increase in canine pruritis as the warmer weather leads to increased levels of common allergens such as pollen, dust mites and flea bites.
Each practice that buys five packs of Apoquel will get one free, subject to a minimum qualifying purchase.
Apoquel is a fast-acting oral therapy for the treatment of canine pruritus associated with allergic dermatitis.
Zoetis says its novel mechanism of action on the Janus Kinase (JAK) enzyme is specifically designed to target the pruritogenic and pro-inflammatory pathways involved in the itch cycle. This, says the company, allows effective reduction of allergic itch regardless of its cause as well as improvement of skin lesions associated with allergic skin diseases and atopic dermatitis.
For more information about the Apoquel Spring offer, contact your Zoetis account manager.