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Lenivia is the first long-acting canine anti-nerve growth factor monoclonal antibody therapy administered three-monthly.
It acts via its binding to nerve growth factor (NGF), a recognised mediator of pain and inflammation.
Julia von Gablenz, Regional President, Europe & Middle East of Zoetis, said: "Lenivia's approval marks a meaningful milestone in our continued innovation for canine osteoarthritis pain."
She added: "With Lenivia's approval, we're proud to bring UK(GB) veterinary professionals a new, long-acting option that can help alleviate osteoarthritis-associated pain and support sustained comfort with a single injection."