The new study will examine the genetic changes that occur in osteosarcoma tumours.
By understanding which genes drive the disease, researchers hope to identify biomarkers – genetic clues that could help diagnose the cancer earlier, predict prognosis for individual patients, and ultimately lead to new treatment options.
The study is looking for dogs with a confirmed or suspected diagnosis of osteosarcoma, whose treatment plan includes surgical removal of the tumour at the QVSH.
With the owner’s permission, tissue samples will be collected from the amputated limb after surgery, as well as from nearby healthy tissue for comparison.
The researchers say participation involves no additional procedures, discomfort, or hospital visits for dogs, and there is no cost to owners for the research elements of the study.
Dr Louise Van Der Weyden, study co-lead at the Wellcome Sanger Institute, said: “Our new study aims to apply genomic sequencing techniques, which have benefited humans, to canine osteosarcoma to uncover what drives these bone tumours and gain a deeper understanding of why they happen.
"We hope that by doing so, we can pave the way for the development of potential biomarkers to help early diagnosis and possibly provide future treatment options for dogs who currently have no cure.”
https://www.hospital.vet.cam.ac.uk/news/new-research-improve-diagnosis-and-treatment-canine-osteosarcoma
oncology@vet.cam.ac.uk
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