TVM has launched Stromease a ready-to-use, anti-collagenase eye drop, indicated for the supportive treatment of corneal ulcers in dogs and cats.

Corneal ulceration is a condition that affects up to 0.8% of cats and dogs in the UK1.

It can have a number of causes such as trauma, foreign bodies or underlying ocular pathology such as tear film insufficiency.

Helen Harrison MRCVS, Veterinary Advisor at TVM, said: "Keratomalacia, or corneal melting, may develop as a complication of an existing corneal ulcer due to the uncontrolled action of proteolytic enzymes. 

"This can lead to corneal perforation and permanent loss of vision.

"Management of keratomalacia requires prompt and aggressive medical treatment to arrest corneal destruction.

"Anti-collagenases, anti-microbials and analgesia are the mainstay of medical therapy, with surgical intervention also indicated for cases requiring tectonic support.

"In addition, certain patients (such as brachycephalic breeds) are more at risk of keratomalacia occurring, therefore anti-collagenases should be considered pre-emptively as part of the treatment plan."

Stromease, which TVM says is the first and only licensed product of its type, contains the active ingredient N-acetylcysteine.

It does not require any prior preparation or special storage.

Presented in a 5ml bottle, Stromease has a three-year unopened shelf-life.

The licensed dose is two drops into the affected eye(s) 3-4 times daily.

 Will Peel, TVM’s product manager said: "Traditionally vets have had to rely on ‘home-made’ anti-collagenase preparations which can be time-consuming to prepare, difficult to store correctly and inconvenient to use.

Stromease is a licensed, anti-collagenase treatment option for corneal ulcers dogs and cats, presented in a user-friendly format."  

For more information visit: or ask your territory manager.


  1. O’Neill, D.G., Lee, M.M., Brodbelt, D.C., Church, D.B., Sanchez, R.F. (2017). Corneal ulcerative disease in dogs under primary veterinary care in England: epidemiology and clinical management. Canine Genet Epidemiol 4, 5.

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