In the trial, published in the Equine Veterinary Journal, synovitis was induced in the right intercarpal joint of 24 horses by intra‐articular injection of 0.5 ng lipopolysaccharide (LPS) of Escherichia coli. After intra‐articular challenge, the nutraceuticals resulted in significantly lower synovial fluid TP, TNCC and PGE 2 compared with placebo, leading the authors to conclude that: "The preventive administration of these nutraceuticals showed anti‐inflammatory effects in this validated synovitis model."
Dr Maarten Oosterlinck DVM, PhD, Dipl. ECVS, one of the authors of the study, said: "Nutraceuticals are often used in the management of osteoarthritis, which is a common cause of chronic lameness in horses but their 'curative' efficacy remains controversial and the quality of the relevant studies is generally low. We set out to evaluate ArtiTec in a well-designed and controlled study. Our research shows that ArtiTec significantly decreased joint inflammation and could be useful in preventing the onset of arthritis."
Cavalor also points to a further field trial of the product by vets in Belgium which showed that it improved lameness in 74% of cases.²
ArtiTec contains glucosamine, MSM, chondroitin, hyaluronic acid, blackcurrant extract, feverfew and pineapple, turmeric root and Boswellia Serrata.
Lieselot Hamerlinck, managing partner at Cavalor said: "Joint supplements account for 34% of the equine supplement market so we know how important these products are to horse owners. Cavalor ArtiTec is the result of an extensive research and development programme and its anti-inflammatory effect has been documented in both scientific studies and a field trial. It can also be used in combination with our other joint supplements, Arti Matrix and Arti Base."
For more information, contact Zebra Products on 01352 763350.
PS: Whilst you're here, take a moment to see our latest job opportunities for vets.
Publishing Editor: Arlo Guthrie
Clinical Editor: Alasdair Hotston Moore MA VetMB CertSAC CertVR CertSAS FRCVS
Facebook | Linkedin | Instagram | Twitter
Learn more about advertising on VetSurgeon.org
VetSurgeon Jobs is the place to advertise and find permanent and locum jobs for veterinary surgeons in England | Scotland | Wales | Ireland and Worldwide. Follow VS Jobs on Facebook | Linkedin | Twitter
Veterinary Anaesthesia | Veterinary Cardiology | Veterinary Dentistry | Veterinary Dermatology | Diagnostic Imaging | Veterinary ECC | Equine Medicine & Surgery | Farm Animal Medicine & Surgery | Veterinary Medicine | Veterinary Neurology Veterinary Oncology | Veterinary Ophthalmology | Veterinary Orthopaedics | Pathology/Cytology | Veterinary Surgery