The research is being carried out by James Glass MRCVS (pictured), a PhD researcher working in the Suicide Behaviour Research Lab at the University of Glasgow, supervised by Professor Rory O'Connor - current president of the International Association for Suicide Prevention.
To take part, vets and student vets are being asked to complete a 15-25 minute survey, which must be done in one sitting.
Survey answers are strictly confidential.
Everyone is invited to participate, regardless of whether or not you have experienced suicidal thoughts, however James cautions that some of the questions may be upsetting for anyone currently experiencing suicidal feelings, and emphasises that participants are free to withdraw from the study at any point by closing the webpage, whereupon any answers already submitted with be discarded.
The study is open until 31st December 2024.
https://tinyurl.com/StudyTeamVet
The study titled “Electrolyte measurements differ between point-of-care and reference analysers in dogs with hypoadrenocorticism” investigated the performance of two point-of-care analysers (IDEXX Catalyst Dx and IDEXX VetStat) against a reference laboratory method for the measurement of blood sodium, potassium and chloride concentrations, as well as sodium-to-potassium ratios, in dogs diagnosed with and treated for hypoadrenocorticism.
Forty-eight dogs with hypoadrenocorticism were enrolled into a prospective cross-sectional study at the University of Glasgow. In total, 329 paired samples were measured on the Catalyst analyser and by the reference laboratory method called an ion selective electrode (ISE), while another 72 paired samples were tested on both the VetStat analyser and by ISE. The clinical effects of any difference in the electrolyte results were investigated.
Sam Fowlie, corresponding author for the paper, said: “Our results indicate that the sodium, potassium and therefore the sodium-to-potassium ratios, as well as the chloride concentrations measured by the Catalyst and VetStat analysers may not be used interchangeably with those from a reference laboratory analyser using an indirect ISE method. Both analysers tended to give higher results than the reference method for all analytes, except for potassium when measured on the VetStat.”
The clinical relevance of the disagreement between these methods was investigated by assessing how often the point-of-care analysers produced results which fell outside their reference range when the ISE method found them to be within reference and vice versa. For the Catalyst, there were 21 cases (6%) with discordant sodium results, 27 cases (8%) with discordant potassium results and 46 cases (14%) with discordant chloride results. The VetStat, meanwhile produced results which disagreed with the ISE method in 19 cases (26%) for sodium, 3 cases (4%) for potassium measurement and 9 cases (13%) for chloride analysis.
Nicola Di Girolamo, Editor of JSAP added: “This study reveals significant systematic differences (“bias”) between the three analysers in this study. Comparing numerical results from different analytical methods – be they point-of-care or reference laboratories – can be dangerous for patients. Clinicians should always use method specific thresholds and, if these are not available (for example the sodium-to-potassium ratios on some analysers), then they should exercise greater caution in their interpretation.”
The full article can be found in the October issue of the Journal of Small Animal Practice and be read online here, open access: https://onlinelibrary.wiley.com/doi/10.1111/jsap.13205.
Reference
Photo: Ian Ramsey
Talking to The Guardian, Hamaseh said: "This has really shocked me. We just discovered at the airport when we went to check in. I want people to know that this is not just happening to refugees. I am a graduate and I have a PhD. It has happened to a person who is working and who pays tax."
Hamaseh, who thought she'd have to find thousands of pounds to pay for an alternative flight home via another country, was quickly saved by a crowdfunding appeal by Women for Independence, which raised over £6000 in a matter of hours. The charity says it is donating everything in excess of the £2600 needed to get Hamaseh home to the Scottish Refugee Council.
Professor Anton Muscatelli, Principal of the University of Glasgow, said: "When I became aware on Saturday evening that one of our postgraduate veterinary students, Dr Hamaseh Tayari, was being prevented from travelling back from a holiday in Costa Rica through the United States and on to Glasgow I was both concerned and appalled. Concerned for the safety and well being of a young woman who, through no fault of her own, was stranded in Central America. Appalled because the reason for her predicament was not because she had done something wrong. Not because she was a danger to the security of the United States. But simply because she holds an Iranian passport."
He added: "Having spoken with Hamaseh I have been hugely impressed at how she is coping with the nightmare situation in which she finds herself. But I have been impressed too by the huge outpouring of support that has been shown across Scotland and the UK, particularly on twitter and through direct emails that have come in to the University from people who are outraged and want to help. All of this, I know, has greatly touched and heartened Hamaseh. I think it also confirms what we all like to believe is true. In this country we value individuals for what they are and the worth they bring, not for the stamp on their passport, the colour of their skin or the religion they practise."
Photo courtesy University of Glasgow
John Swinney MSP, Cabinet Secretary for Finance and Sustainable Growth, oficially opened the award-winning £10.5 million Small Animal Hospital for the Faculty of Veterinary Medicine, University of Glasgow today.
Designed by Archial Architects, the Small Animal Hospital provides state of the art services for animal owners and referring practitioners throughout Scotland and Northern England, including advanced diagnostic, therapeutic and surgical techniques.
Archial's design for the Small Animal Hospital has already won a string of awards, including the prestigious RIAS Andrew Doolan Best Building in Scotland Award, a RIBA Regional Award and the Supreme Award from the Glasgow Institute of Architects.
Archial Architects has confirmed that it is to donate £2,500 from the Andrew Doolan Prize fund to the Small Animal Hospital.
A research project funded by equine charity The Horse Trust has succeeded in killing equine sarcoid cells in vitro by silencing a gene in the virus that causes sarcoids. The researchers are now hoping to obtain funding for clinical trials using the new technique, which could result in a more effective, non-toxic treatment for sarcoids.
Sarcoids are skin tumors caused by infection with the Bovine Papillomavirus (BPV). They are the most common type of tumour found in horses - the estimated prevalence in the UK is 6-7%. Although the disease is rarely life threatening, many horses with sarcoids are euthanased because the condition is untreatable or because the horse is unsellable. Currently there is no universally effective treatment for sarcoids and if treatment fails the sarcoids will often come back worse.
However, research that was given funding by The Horse Trust offers a potential ray of hope for owners of horses affected by sarcoids. The research was published in Virus Research journal earlier this year.
The research, which was led by Professor Lubna Nasir of the University of Glasgow, found that by inhibiting the activity of a particular viral protein within sarcoid cells, the amount of viral DNA in the cells reduced. This led to a reduction in the growth of the sarcoid cells and caused the cell to die by Programmed cell-death (PCD). The researchers believe that PCD occurs because the sarcoid cells become reliant on the virus.
Professor Nasir said: "This could potentially be a major breakthrough in the treatment of sarcoids. We are now seeking funding to use this technique in clinical trials on horses that have sarcoids."
The research team inhibited the activity of a viral protein called E2, which is needed by BPV to replicate. They used a novel approach termed 'gene silencing' to suppress the activity of the gene that codes the E2 protein. The research was carried out in vitro on fibroblast cells, which had been cultured from sarcoid tissue removed from animals during surgery.
As this research was carried out in vitro, the researchers will now need to see if they can replicate the results in vivo, by developing a way of targeting the sarcoid cells in horses.
"One of the challenges with gene silencing is administering it within clinical setting - as you need to get molecules into every cell. As sarcoids are on the surface of a horse, we think administration should be relatively easy - potentially by injecting or applying a cream to the sarcoid," said Professor Nasir. "If we are able to successfully develop this technique it would be a non-toxic and easy to administer treatment for horses affected by this distressing condition."
Nasir's research could also have an impact on the treatment of lesions in cattle, which are also caused by BPV. Around 50% of cattle in the UK are estimated to have lesions. It may also help with the treatment of Human Papillomavirus (HPV) infections in humans. HPV, which is similar to BPV, can lead to various cancers in humans including cervical and vaginal cancer.
Paul Jepson, Chief Executive and Veterinary Director of The Horse Trust said: "We are really excited that the research we have funded could lead to a major breakthrough in the treatment of sarcoids."