https://www.vetsurgeon.org/w/veterinary-research/71/pharmacokinetics-of-cetirizine-in-healthy-catsIn this wiki, members may publish case studies and reports, presentations, short communications, research papers and the results of clinical audits relating to small animals, for open review / discussion by all members of VetSurgeon.en-USTelligent Community 10https://www.vetsurgeon.org/w/veterinary-research/71/pharmacokinetics-of-cetirizine-in-healthy-catsThu, 08 Oct 2009 17:04:18 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:2ab83def-2c77-45e3-8e21-bb695503ae55Arlo Guthriehttps://www.vetsurgeon.org/w/veterinary-research/71/pharmacokinetics-of-cetirizine-in-healthy-cats#commentsCurrent Revision posted to Abstracts, Short Communications &amp; Research by Arlo Guthrie on 10/8/2009 5:04:18 PM<br /> <h3 align="left">Mark Papich and others, North Carolina State University</h3> <p align="left">Cetirizine is the active metabolite of the antihistamine agent hydroxyzine and is preferred for use in treating human skin allergies because it has less of a sedative effect than the parent compound. The authors investigate the pharmacokinetics of cetirizine in healthy cats, using high performance liquid chromatography&nbsp;to measure plasma levels up to 24 hours after a single 5mg dose of cetirizine dihydrochloride.</p> <p align="left">Concentrations remained above the effective human concentration for at least 24 hours after treatment. </p> <p align="left"><em><a target='_blank' href="http://www.avma.org/journals/ajvr/ajvr_index.asp">American Journal of Veterinary Research 69 (5): 670-674</a></em>.</p> <p align="left">Abstract reproduced by kind permission of <em>Veterinary Practice</em> magazine</p> <p align="left"><img src="/resized-image.ashx/__size/550x0/__key/CommunityServer.Wikis.Components.Files/veterinary-research/2605.abstracts_2D00_logo.gif" border="0" alt="" /></p><div style="clear:both;"></div> <div style="font-size: 90%;">Tags: cetirizine, Dermatology, Cats</div> https://www.vetsurgeon.org/w/veterinary-research/71/pharmacokinetics-of-cetirizine-in-healthy-cats/revision/1Wed, 17 Jun 2009 16:51:35 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:2ab83def-2c77-45e3-8e21-bb695503ae55Arlo Guthriehttps://www.vetsurgeon.org/w/veterinary-research/71/pharmacokinetics-of-cetirizine-in-healthy-cats#commentsRevision 1 posted to Abstracts, Short Communications &amp; Research by Arlo Guthrie on 6/17/2009 4:51:35 PM<br /> <h3 align="left">Mark Papich and others, North Carolina State University</h3> <p align="left">Cetirizine is the active metabolite of the antihistamine agent hydroxyzine and is preferred for use in treating human skin allergies because it has less of a sedative effect than the parent compound. The authors investigate the pharmacokinetics of cetirizine in healthy cats, using high performance liquid chromatography&nbsp;to measure plasma levels up to 24 hours after a single 5mg dose of cetirizine dihydrochloride.</p> <p align="left">Concentrations remained above the effective human concentration for at least 24 hours after treatment. </p> <p align="left"><em><a target='_blank' href="http://www.avma.org/journals/ajvr/ajvr_index.asp">American Journal of Veterinary Research 69 (5): 670-674</a></em>.</p> <p align="left">Abstract reproduced by kind permission of <em>Veterinary Practice</em> magazine</p> <p align="left"><img border="0" src="/resized-image.ashx/__size/550x0/__key/CommunityServer.Wikis.Components.Files/veterinary-research/2605.abstracts_2D00_logo.gif" alt="" /></p><div style="clear:both;"></div> <div style="font-size: 90%;">Tags: cats, dermatology, cetirizine</div>