https://www.vetsurgeon.org/w/veterinary-research/52/clinical-effects-and-outcome-of-feline-permethrin-spot-on-poisonings-reported-to-the-veterinary-poisons-information-service-vpis-londonIn this wiki, members may publish case studies and reports, presentations, short communications, research papers and the results of clinical audits relating to small animals, for open review / discussion by all members of VetSurgeon.en-USTelligent Community 10https://www.vetsurgeon.org/w/veterinary-research/52/clinical-effects-and-outcome-of-feline-permethrin-spot-on-poisonings-reported-to-the-veterinary-poisons-information-service-vpis-londonThu, 08 Oct 2009 17:00:52 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:cc30c0e6-71c3-487d-a79d-9c0617d74248Arlo Guthriehttps://www.vetsurgeon.org/w/veterinary-research/52/clinical-effects-and-outcome-of-feline-permethrin-spot-on-poisonings-reported-to-the-veterinary-poisons-information-service-vpis-london#commentsCurrent Revision posted to Abstracts, Short Communications &amp; Research by Arlo Guthrie on 10/8/2009 5:00:52 PM<br /> <p> <h3 align="left">Nicholas Sutton and others, Veterinary Poisons Information Service</h3> </p> <p align="left">Permethrin is a pyrethroid insecticide used in topical (spot-on) flea treatments for dogs. These products are contraindicated in cats because of a high risk of toxicosis but there have been many reports of owners ignoring or not noticing warnings on the product packaging.</p> <p align="left">The authors describe the findings in 286 cases of inappropriate use in cats reported by veterinary practitioners to the Veterinary Poisons Information Service in London. In 96.9% of these cases, the cats showed clinical signs, with increased muscle activity (twitching, tremor, fasciculations or convulsions) occurring in 88% of cases.</p> <p align="left">The duration of this muscle activity was long, with convulsions lasting for an average of 39 hours and tremors for 32 hours. Recovery typically occurred within two to three days but in some cases it took up to seven days. In 10.5% of cases the affected cat died.</p> <p align="left"> <p><i> <p align="left"><a target='_blank' href="http://www.elsevier.com/wps/find/journaldescription.cws_home/623051/description#description">Journal of Feline Medicine and Surgery 9 (4): 335-339</a>.</p> </i></p> </p> <p> <p align="left">Abstract reproduced by kind permission of <em>Veterinary Practice</em> magazine.</p> </p> <p align="left"><a href="/cfs-file.ashx/__key/CommunityServer.Wikis.Components.Files/veterinary-research/2605.abstracts_2D00_logo.gif"><img src="/resized-image.ashx/__size/550x0/__key/CommunityServer.Wikis.Components.Files/veterinary-research/2605.abstracts_2D00_logo.gif" border="0" alt="" /></a></p><div style="clear:both;"></div> <div style="font-size: 90%;">Tags: ectoparasites, permethrin, Cats</div> https://www.vetsurgeon.org/w/veterinary-research/52/clinical-effects-and-outcome-of-feline-permethrin-spot-on-poisonings-reported-to-the-veterinary-poisons-information-service-vpis-london/revision/1Mon, 15 Jun 2009 17:29:35 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:cc30c0e6-71c3-487d-a79d-9c0617d74248Arlo Guthriehttps://www.vetsurgeon.org/w/veterinary-research/52/clinical-effects-and-outcome-of-feline-permethrin-spot-on-poisonings-reported-to-the-veterinary-poisons-information-service-vpis-london#commentsRevision 1 posted to Abstracts, Short Communications &amp; Research by Arlo Guthrie on 6/15/2009 5:29:35 PM<br /> <p> <h3 align="left">Nicholas Sutton and others, Veterinary Poisons Information Service</h3> </p> <p align="left">Permethrin is a pyrethroid insecticide used in topical (spot-on) flea treatments for dogs. These products are contraindicated in cats because of a high risk of toxicosis but there have been many reports of owners ignoring or not noticing warnings on the product packaging.</p> <p align="left">The authors describe the findings in 286 cases of inappropriate use in cats reported by veterinary practitioners to the Veterinary Poisons Information Service in London. In 96.9% of these cases, the cats showed clinical signs, with increased muscle activity (twitching, tremor, fasciculations or convulsions) occurring in 88% of cases.</p> <p align="left">The duration of this muscle activity was long, with convulsions lasting for an average of 39 hours and tremors for 32 hours. Recovery typically occurred within two to three days but in some cases it took up to seven days. In 10.5% of cases the affected cat died.</p> <p align="left"> <p><i> <p align="left"><a target='_blank' href="http://www.elsevier.com/wps/find/journaldescription.cws_home/623051/description#description">Journal of Feline Medicine and Surgery 9 (4): 335-339</a>.</p> </i></p> </p> <p> <p align="left">Abstract reproduced by kind permission of <em>Veterinary Practice</em> magazine.</p> </p> <p align="left"><a href="/cfs-file.ashx/__key/CommunityServer.Wikis.Components.Files/veterinary-research/2605.abstracts_2D00_logo.gif"><img border="0" src="/resized-image.ashx/__size/550x0/__key/CommunityServer.Wikis.Components.Files/veterinary-research/2605.abstracts_2D00_logo.gif" alt="" /></a></p><div style="clear:both;"></div> <div style="font-size: 90%;">Tags: cats, ectoparasites, permethrin</div>