Veterinary Pathology & Cytology

Piloleiomyosarcoma in cats: Histological and immunohistochemical features

Arlo Guthrie — Mon, 29 Jul 2024 15:53:28 GMT

In the following film, Karina Fresneda DVM DiplACVP, anatomic pathologist at NationWide Laboratories, discusses "Piloleiomyosarcoma in cats: Histological and immunohistochemical features", a paper by Eileen Larsen, Allison M. Watson and Juan F. Muñoz Gutiérrez

Speaker Bio: Karina Fresneda DVM DiplACVP
Karina graduated from the National University of the Centre of Buenos Aires Province in Argentina in 2000, and after two years of training, she became a Specialist in Anatomo-histopathological Veterinary Diagnosis. She has been teaching in Infectious Diseases at the same University for 15 years. At the same time, she was gaining experience, on her clinic and laboratory, as a clinician and working on clinical pathology, cytology, and histopathology. She took a 3-year Residency in Anatomic Veterinary Pathology in the University of California, Davis, where she received intensive training on this field. She also enjoys teaching different courses on clinical pathology, cytology, and histopathology.

Reference
Guisado FR, Castro PL. Piloleiomyosarcoma in cats: Histological and immunohistochemical features. Vet Pathol. 2022 Jan;59(1):57-62. doi: 10.1177/03009858211042582. Epub 2021 Sep 16. PMID: 34525874.

NationWide Laboratories, a member of the NVS Group, offers a comprehensive range of testing options, quick turnaround times, and competitive pricing, as well as digital pathology services and courier collections in eligible parts of the UK. Our expert teams provide guidance on relevant testing for companion, exotic, and farm animals, with full interpretation in areas such as biochemistry, haematology, cytology, histopathology, endocrinology, and microbiology. By partnering with NationWide Laboratories, veterinary practices can benefit from expertise in veterinary diagnostics, along with NVS Group resources including wholesale products, laboratory services, industry-leading practice management software, and NVS own products – all under one roof, allowing you to focus on what matters most – providing exceptional service to your patients.

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Periarticular plasma cell tumors in cats

Arlo Guthrie — Mon, 29 Jul 2024 15:40:52 GMT

In the following film, Karina Fresneda DVM DiplACVP, anatomic pathologist at NationWide Laboratories, discusses "Periarticular plasma cell tumors in cats", a paper by Linden E. Craig, and Danielle E. Lieske.

Bio: Karina Fresneda DVM DiplACVP

Karina graduated from the National University of the Centre of Buenos Aires Province in Argentina in 2000, and after two years of training, she became a Specialist in Anatomo-histopathological Veterinary Diagnosis. She has been teaching in Infectious Diseases at the same University for 15 years. At the same time, she was gaining experience, on her clinic and laboratory, as a clinician and working on clinical pathology, cytology, and histopathology. She took a 3-year Residency in Anatomic Veterinary Pathology in the University of California, Davis, where she received intensive training on this field. She also enjoys teaching different courses on clinical pathology, cytology, and histopathology.

Reference
Craig LE, Lieske DE. Periarticular plasma cell tumors in cats. Vet Pathol. 2022 Mar;59(2):264-268. doi: 10.1177/03009858211048621. Epub 2021 Nov 11. PMID: 34763582.

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Intranasal mast cell tumors: Clinical, immunohistochemical, and molecular features in 20 dogs

Arlo Guthrie — Mon, 29 Jul 2024 15:32:09 GMT

In the following film, Karina Fresneda DVM DiplACVP, anatomic pathologist at NationWide Laboratories, discusses "Intranasal mast cell tumors: Clinical, immunohistochemical, and molecular features in 20 dogs", a paper by Eileen Larsen, Allison M. Watson and Juan F. Muñoz Gutiérrez

Reference
Larsen E, Watson AM, Muñoz Gutiérrez JF. Intranasal mast cell tumors: Clinical, immunohistochemical, and molecular features in 20 dogs. Vet Pathol. 2022 Nov;59(6):915-921. doi: 10.1177/03009858221109100. Epub 2022 Jul 5. PMID: 35787192.

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Reproductive tract neoplasia in adult female Asian elephants (Elephas maximus)

Arlo Guthrie — Mon, 29 Jul 2024 15:18:08 GMT

In the following film, Marvin Firth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Reproductive tract neoplasia in adult female Asian elephants (Elephas maximus)", a paper by Jennifer A. Landolfi, Patricia M. Gaffney, Rita McManamon, Nicole L. Gottdenker, Angela E. Ellis, Raquel R. Rech, Sushan Han, Linda J. Lowenstine, Dalen Agnew, Michael M. Garner, Denise McAloose, Charlotte Hollinger, Judy St. Leger, Scott P. Terrell, Mary Duncan, Allan P. Pessier.

Speaker Bio: Dr Marvin Firth BVSc (Hons.), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS
Marvin graduated from Liverpool in 2009 with honours and distinction. He has gained experience in first and second opinion small, large animal and equine practice throughout the south of England and has undertaken research in pregnancy loss in mares. Marvin has undertaken a variety of externships in anatomic pathology including in the US and Europe and has undertaken residency training at Cambridge and Surrey universities. In 2019, Marvin obtained the Diploma in Forensic Medical Sciences and is studying towards the ACVP and Royal College of Pathologist’s board certifications, achieving DipRCPath and ACVP Phase 1 in 2022. He is the RC Pathologists Trainee representative in Veterinary Anatomic Pathology.

Reference
1. Landolfi JA, Gaffney PM, McManamon R, et al. Reproductive tract neoplasia in adult female Asian elephants (Elephas maximus). Veterinary Pathology. 2021;58(6):1131-1141. doi:10.1177/03009858211031843

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Pathological & Immunohistochemical Analyses of Equine Glanders Using Anti-BpaB Antibody

Arlo Guthrie — Mon, 29 Jul 2024 14:57:07 GMT

In the following film, Marvin Firth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Pathological and Immunohistochemical Analyses of Naturally Occurring Equine Glanders Using an Anti-BpaB Antibody", a paper by Ochbayar Erdemsurakh, Baatarjargal Purevdorj, Khurtsbaatar Ochirbat, Atsushi Kobayashi, and Takashi Kimura.

Reference
Erdemsurakh O, Purevdorj B, Ochirbat K, Adilbish A, Vanaabaatar B, Aoshima K, Kobayashi A, Kimura T. Pathological and Immunohistochemical Analyses of Naturally Occurring Equine Glanders Using an Anti-BpaB Antibody. Vet Pathol. 2020 Nov;57(6):807-811. doi: 10.1177/0300985820953422. Epub 2020 Sep 4. PMID: 32885748.

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Clinical and Pathological Features in Horses With Advanced Arytenoid Chondritis

Arlo Guthrie — Mon, 29 Jul 2024 14:46:54 GMT

In the following film, Marvin Firth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Clinical and Pathological Features in Horses With Advanced Arytenoid Chondritis", a paper by Pompei Bolfa, Marta Cercone, Michelle M. Dennis, Anne Conan, Bernard Grevemeyer, and Norm G. Ducharme.

Reference
1. Bolfa P, Cercone M, Dennis MM, Conan A, Grevemeyer B, Ducharme NG. Clinical and Pathological Features in Horses With Advanced Arytenoid Chondritis. Veterinary Pathology. 2021;58(1):91-102. doi:10.1177/0300985820967452

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Pathogenesis of Equid Alphaherpesvirus 1 Infection in the Central Nervous System of Mice

Arlo Guthrie — Mon, 29 Jul 2024 14:32:06 GMT

In the following film, Marvin Firth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Pathogenesis of Equid Alphaherpesvirus 1 Infection in the Central Nervous System of Mice", a paper by Leonardo P. Mesquita D, Rafael C. Costa, Laís L. R. Mesquita, Maria do Carmo C.S. H. Lara, Eliana M. C. Villalobos, Claudia M. C. Mori, Enio Mori, Elizabeth W. Howerth, and Paulo C. Maiorka.

Reference
1. Ushio N, Chambers JK, Watanabe K, Kayano M, Uchida K. Age-Related Arteriolar Changes With Lipid and Amyloid Deposits in the Gonads of Dogs. Vet Pathol. 2021 May;58(3):558-567. doi: 10.1177/0300985821996670. Epub 2021 Mar 9. PMID: 33686886.

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Oral Lesions in Captive Nondomestic Felids With a Focus on Odontogenic Lesions

Arlo Guthrie — Mon, 29 Jul 2024 14:16:13 GMT

In the following film, Marvin Firth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Oral Lesions in Captive Nondomestic Felids With a Focus on Odontogenic Lesions", a paper by Katherine L. Scott, Michael M. Garner, Brian G. Murphy, and Elise E. B. LaDouceur.

Reference
1. Scott KL, Garner MM, Murphy BG, LaDouceur EEB. Oral Lesions in Captive Nondomestic Felids With a Focus on Odontogenic Lesions. Vet Pathol. 2020 Nov;57(6):880-884. doi: 10.1177/0300985820943539. Epub 2020 Oct 5. PMID: 33016248.

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Nonocular Melanocytic Neoplasia in Cats

Arlo Guthrie — Mon, 29 Jul 2024 13:42:42 GMT

In the following film, Marvin FIrth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Nonocular Melanocytic Neoplasia in Cats: Characterization and Propopsal of a Histologic Classification Scheme to More Accurately Predict Outcome", a paper by Rachel Pittaway, Melanie J Dobromylskyj, Kerstin Erles, Charles E Pittaway, Alejandro Suárez-Bonnet, Yu-Mei Chang, Simon L Priestnall.

Reference
1. Pittaway R, Dobromylskyj MJ, Erles K, Pittaway CE, Suárez-Bonnet A, Chang YM, Priestnall SL. Nonocular Melanocytic Neoplasia in Cats: Characterization and Proposal of a Histologic Classification Scheme to More Accurately Predict Clinical Outcome. Vet Pathol. 2019 Nov;56(6):868-877. doi: 10.1177/0300985819854435. Epub 2019 Jun 20. PMID: 31221042.

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Age-Related Arteriolar Changes With Lipid and Amyloid Deposits in the Gonads of Dogs

Arlo Guthrie — Mon, 15 Jul 2024 17:47:54 GMT

In the following film, Marvin Firth BVSc (Hons), DipRCPath, DipFMS, AFHEA, MRSB, MRCVS, anatomic pathologist at NationWide Laboratories, discusses "Age-Related Arteriolar Changes With Lipid and Amyloid Deposits in the Gonads of Dogs", a paper by Nanako Ushio, James K Chambers, Kenichi Watanabe , Mitsunori Kayano and Kazuyuki Uchida.

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Leishmania species amastigotes

Arlo Guthrie — Thu, 04 Apr 2019 18:08:34 GMT

Bone marrow cytology showing macrophages with numerous intracellular organisms consistent with Leishmania species amastigotes.

See: www.vetsurgeon.org/.../vigilance-urged-after-first-uk-case-of-leishmaniosis-caught-from-another-dog.aspx

Photo credit Charalampos Attipa

You're in trouble (geddit?)

Liz Barton — Mon, 15 Oct 2018 22:51:45 GMT

This sample was taken by cystocentesis from a dog with no history of PUPD, just malaise and inappropriate urination. Yuck!

Mitotic Figures

Liz Barton — Mon, 15 Oct 2018 22:40:24 GMT

These are FNAs from 2 lymphomas - plenty of mitoses indicating a high grade. The first picture shows spindles in longitudinal and transverse section. Always amazes me I'm actually looking at genetic material dividing across the cell. When aspirating these huge peripheral lymph nodes, the material is often quite fluid and look grossly purulent.

Bronchial mass impression smear

Liz Barton — Tue, 17 Jul 2018 21:40:54 GMT

9yr DSH with cough, soft tissue opacity left caudodorsal lung field. Bronchoscopy revealed a soft tissue mass blocking a main bronchial branch. The images are from an impression smear of the mass prior to sending for histopath, which is pending. What do you think? I'll post the histopath results when they're in

Mast Cell Tumour

Liz Barton — Tue, 03 Jul 2018 10:20:42 GMT

Impression smear post surgery