Oral papillomatosis

RE: Oral papillomatosis

Julian Earl — Mon, 31 Jan 2022 13:50:20 GMT

Thanks Rob,

I was just reporting a personal observation from two cases more but I bow to your superior knowledge! Than you again. It does not disprove directly my suggestion that after diathermy and extensive removal, the resultant inflammation of healing is involved in the animal being able to kill off and slough he emainder? Nor would it prevent recurrence as far as can see either? I shall await further research on this opicin thef uture! Over to you Rob!!

stay safe, stay well. My new friend if you accept he request that is??! Cheers!

RE: Oral papillomatosis

Rob Davis — Mon, 31 Jan 2022 12:57:14 GMT

[quote userid="3094" url="~/001/nonclinical/f/life-in-practice-discussions/30171/oral-papillomatosis/235494#235494"]seems to trigger the remainder also slouf=ghing/disappearind=g as well [/quote]

The problem is that these lesions almost always spontaneously regress on their own, so it is very difficult causality of the treatment rather than correlation. Also from Wiggs: "there is some evidence that surgical excision of oral papillomas is associated with latent infection and increased recurrence". Who knows.....?

RE: Oral papillomatosis

Julian Earl — Sat, 29 Jan 2022 21:20:43 GMT

I hadseen a number of these oral cases and often surgically removing the majority, often using Diathermy by choice, seems to trigger the remainder also slouf=ghing/disappearind=g as well . I am unsure of the machanism unless it has caused a generalised inflammatory response in the oral mucosa that is enough to kill the papillomata off? \\\\\\\\very rfewarding when it happens though!!

RE: Oral papillomatosis

Rob Davis — Fri, 28 Jan 2022 15:26:28 GMT

From Wigg's Veterinary Dentistry: "Treatments for persistent canine papilloma lesions are mostly anecdotal and it is hard to discriminate between spontaneous regression and therapeutic effect. Surgical excision and laser treatment are frequently used in veterinary medicine but there are no published reports of the success rate.....Other anecdotally reported treatments include imiquimod, interferon-alpha2a, autologous or recombinant papilloma virus vaccine and homeopathic tarantula venom. Azythromycin had a 100% success rate in a placebo-controlled trial in 17 dogs."

I've never had to treat any personally. I would be concerned about some reason for immunosuppression in this dog given concurrent demodicosis and severe papilloma lesions...

RE: Oral papillomatosis

Julian Earl — Fri, 28 Jan 2022 14:58:21 GMT

There sed tobe a product Anthiomaline that was licencedfor this IIRC. But I am not sure how well it really worked? The growths tend to slough off on their own eventually thoughcan take very many weeks IME! Antuiomaline also tended to make the dogs vomit as well so be arned!