Self resolving diabetes insipidus.

RE: Self resolving diabetes insipidus.

Lucy Fleming — Fri, 30 Sep 2016 16:54:53 GMT

[quote user="Clive Ansell"]Boxernoma - good one [/quote]

I can't claim credit for that, I'm sure I saw it on here somewhere...

RE: Self resolving diabetes insipidus.

Anthony Dennison — Thu, 29 Sep 2016 09:18:22 GMT

[quote user="Clive Ansell"]dog was PTS because seizures were increasing in frequency and duration and owners refused to trial Phenobarbitone. [/quote]

The idiocy of some people astounds me. And I'm surprised I'm still getting surprised by it.

RE: Self resolving diabetes insipidus.

Clive Ansell — Wed, 28 Sep 2016 10:06:51 GMT

[quote user="Lucy Fleming"]

Has its intra-cranial boxernoma got worse and is now non-functional hence the resolution of DI signs?

I don't like to be cynical (ok that's a lie, I love to be cynical), but it's a 12 year old boxer...

[/quote]

Boxernoma - good one

That was my first thought; given he's a boxer neoplasia has to be the leading differential.

I wonder what any neoplasm was producing that caused pu/pd? ACTH stim tests were always normal, so not cortisol via acth, and true CDI is a lack of ADH production. interesting none the less.

Thanks for your thoughts everyone - dog was PTS because seizures were increasing in frequency and duration and owners refused to trial Phenobarbitone.

RE: Self resolving diabetes insipidus.

Robin Grimmer — Mon, 26 Sep 2016 20:51:42 GMT

Pituitary macroadenoma.

RE: Self resolving diabetes insipidus.

Noweia — Mon, 26 Sep 2016 20:46:05 GMT

Was going to suggest brain neoplasia but Lucy got there first! Could there be a tumour causing polydipsia that has now grown big enough to cause seizures?

We've had one Cushingoid boxer that stopped being Cushingoid shortly before developing seizures and rapidly deteriorating - we figured the pituitary mass had grown big enough that either its blood supply was insufficient or the resulting pressure had killed off the functioning cells, hence stopping the clinical signs.

RE: Self resolving diabetes insipidus.

Lucy Fleming — Mon, 26 Sep 2016 17:41:14 GMT

Has its intra-cranial boxernoma got worse and is now non-functional hence the resolution of DI signs?

I don't like to be cynical (ok that's a lie, I love to be cynical), but it's a 12 year old boxer...

RE: Self resolving diabetes insipidus.

Clive Ansell — Mon, 26 Sep 2016 17:32:13 GMT

Looking at previous notes (I wasn't there) it seems the deprivation test was fairly thorough, and carried out as well as it could be; conducted over 24 hours and they demonstrated weight loss with and on going low SG urine.

Just seems unusual that it should resolve suddenly and coincide with the seizures.

My first thought on seeing this dog (and owners) would have been Psychogenic pd, very stressed dog and ridiculously overbearing neurotic owners.

RE: Self resolving diabetes insipidus.

Martin Atkinson — Mon, 26 Sep 2016 17:17:35 GMT

There is rarely a clear cut diagnosis in these cases. I wonder how thoroughly the deprivation test was performed and a lot of non DI polydypsia cases respond to Desmopressin which is why its not overly helpful. I suspect most 'DI' cases are psychogenic and will improve as quickly as they appeared. I've seen a few like this in my career.

Perhaps it was cured by self administered homeopathy - using water to treat polydypsia must be a winner.