https://www.vetsurgeon.org/f/non-clinical-questions/24374/advise-re-puppy-scoliosis-etc-owner-breeders I saw a pup for its first injection at 6 weeks - French bulldog, It had been seen at 2 days old just for a quick post whelp check etc and all seemed ok. I t presented with 3 siblings all very lively and mentally active, this one pup is flattened topen-USTelligent Community 10