Addisons disease

Re: Addisons disease

Rajat — Fri, 27 Jul 2012 01:45:37 GMT

[quote user="Mark Holmes"]I hope its practice policy to give you a strong coffee before letting you near a patient![/quote]

I usually have no less than 3! Coffee is my lifeblood...No seriously, my maths is usually better than that coffee or no coffee!

Re: Addisons disease

Mark Holmes — Thu, 26 Jul 2012 12:12:18 GMT

[quote user="Rajat"]

haha early morning maths you are quite right

5mg it is

I stand corrected

[/quote]

I hope its practice policy to give you a strong coffee before letting you near a patient!

Re: Addisons disease

Rajat — Thu, 26 Jul 2012 10:46:00 GMT

haha early morning maths you are quite right

5mg it is

I stand corrected

Re: Addisons disease

Michael Woodhouse — Thu, 26 Jul 2012 10:04:55 GMT

[quote user="Mark Holmes"] I think your maths must work differently to mine as I get it to 5mg ie 1/5 or 0.2 of 25.[/quote]

Re: Addisons disease

Mark Holmes — Thu, 26 Jul 2012 08:39:14 GMT

[quote user="Rajat"]

[quote user="Michael Woodhouse"]

[quote user="Mark Holmes"]

I had considered suggesting a 5mg pred on a gun day, but I have no idea if that is just complete rubbish or a well reasoned precaution.

[/quote]

Gun dogs work bloody hard. I think that is a very wise precaution.

[/quote]

I agree- but maybe worth trying to work out what the physiological dose for the dog would be - the figure I remember is 0.2mg/kg/prednisolone per day, which for a 25 kg dog works out as 1 mg pred.

[/quote] I think your maths must work differently to mine as I get it to 5mg ie 1/5 or 0.2 of 25.

Re: Addisons disease

Rajat — Thu, 26 Jul 2012 08:14:15 GMT

[quote user="Michael Woodhouse"]

[quote user="Mark Holmes"]

I had considered suggesting a 5mg pred on a gun day, but I have no idea if that is just complete rubbish or a well reasoned precaution.

[/quote]

Gun dogs work bloody hard. I think that is a very wise precaution.

[/quote]

I agree- but maybe worth trying to work out what the physiological dose for the dog would be - the figure I remember is 0.2mg/kg/prednisolone per day, which for a 25 kg dog works out as 1 mg pred.

Re: Addisons disease

Michael Woodhouse — Wed, 25 Jul 2012 19:38:15 GMT

[quote user="Mark Holmes"]

I had considered suggesting a 5mg pred on a gun day, but I have no idea if that is just complete rubbish or a well reasoned precaution.

[/quote]

Gun dogs work bloody hard. I think that is a very wise precaution.

Re: Addisons disease

Martin Atkinson — Wed, 25 Jul 2012 17:02:28 GMT

[quote user="Mark Holmes"]I had considered suggesting a 5mg pred on a gun day, but I have no idea if that is just complete rubbish or a well reasoned precaution. [/quote] I think it depends on whether they are cortico-steroid dependent and it would be more reasonable to make the decision based on monitoring electrolytes/BUN/Creatinine and the leucogram than having a one size fits all approach. We have an 11 month old ShihTzu which was diagnosed at 7 months, and is maintained nicely on Florinef although it needed some preds to start for a couple of weeks. As it happened it was booked in for castration for behavioural reasons recommended by Roger Mugford and as I was considering giving it cortico-steroids pre surgery it developed what is probably a food allergy so is on steroids for that and being tapered off while we do a food trial. Otherwise I would probably just put them on a saline drip under GA as a precaution unless I knew the surgery would be particularly stressful.

Re: Addisons disease

Mark Holmes — Wed, 25 Jul 2012 16:19:32 GMT

I had considered suggesting a 5mg pred on a gun day, but I have no idea if that is just complete rubbish or a well reasoned precaution.

Re: Addisons disease

Martin Atkinson — Wed, 25 Jul 2012 16:09:02 GMT

I've seen Addisons in all shapes and sizes. As you say shouldn't be a particular problem but if it is gluco-corticoid as well as mineralo-corticoid deficient then the stress of extreme exercise could theoretically be an issue so I would warn them not to over-do it. There was an issue discussed in the veterinary journals a while ago about 'gun-dog collapse syndrome' which I believe was over-exercise induced hypoglycaemia (cf 'hitting the wall' in a marathon) and a common sense approach to feeding and exercise should take care of that. Don't know just a thought.