https://www.vetsurgeon.org/f/clinical-questions/9605/resolving-hypothyroidism The patient is an 11 year old spayed Cocker Spaniel belonging to one of our nurses. She was diagnosied with hypothyroidism in 2005 and started on soloxine (pre-treatment thyroxine level was &lt;2nmol/l and TSH was 2.0 ng/ml). Until July 2007 she remaineden-USTelligent Community 10https://www.vetsurgeon.org/thread/47650?ContentTypeID=1Fri, 21 Oct 2011 12:56:03 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:1ab1d85a-44bf-4b2c-a9e8-c73f587d8e4bRob Davis<p>Hi Andy, thanks for your thoughts. As far as I&#39;m aware there has not been any change inb diet etc, but I will double check. No thyroid nodules palpable, ran routine bloods and all normal. I&#39;ve decided to halve the soloxine rather than stop completely and she is coming back to see me in another month. I&#39;ll keep you posted with progress...</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/47573?ContentTypeID=1Thu, 20 Oct 2011 14:26:22 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:dc792389-8691-4f55-98dc-f982170242ccAndrew Kent<p>Interesting case Rob, results at time of treatment certainly look pretty conclusive.</p> <p>Has there been any change in administration of soloxine with regard to feeding etc? Or diet change? This can have an impact on bioavailability of thyroid meds.</p> <p>Any palpable thyroid nodules?</p> <p>I guess if it was me I might try stopping the thyroid meds and test again to see what happens, I suppose as she is losing weight this may then have an impact on her thyroid dosing so the other thought may be to see if there is another non-thyroid reason for weight loss?</p> <p>Andy</p><div style="clear:both;"></div>