Cat with hyperlipidaemia

Re: Cat with hyperlipidemia

Claire Fisher — Wed, 17 Aug 2011 14:06:24 GMT

[quote user="Michael Woodhouse"]

[quote user="Claire Fisher"]I thought it was the other way round - normal if they've eaten recently but abnormal if fasted for 12 hours prior to sampling?[/quote]

I could be wrong here, and the cat lovers or pathologist are free to correct me. My understanding was glycogen stores only last a day or so and then we resort to breaking down stored fat (and hence raised cholesterol) and protein breakdown. It is the starvation due to insulin resistance in diabetics that cause the continued breakdown of stored fat and the classic lipaemic serum and raised cholesterol.

We all know cats are susceptible to fatty liver and how vital nutrition support is in this species.

IIRC the reason it's there post prandial is due to the mechanism of absorbing fats (via the lymphatics).

[/quote]

Thanks, he'd been anorexic for a day or so, weighs 4kg BCS 3/5 so not what I'd class as overweight.

He's doing well now though so we have decided to monitor for now. I think it was the degree of lipaemia that made me panic - the last one that had pure fat for serum was later confirmed at biopsy to have hepatic lipidosis

Re: Cat with hyperlipidemia

Richard Fox — Wed, 17 Aug 2011 10:54:17 GMT

Micheal's right - I assumed that this had been exuded - i.e. anorectic fat cat but if not yes defo

However if the cat is eating OK and the lipaemia persists then I would be concerned :)

An FNA of the liver can be used to help indicate fatty liver syndrome?

Re: Cat with hyperlipidemia

Michael Woodhouse — Tue, 16 Aug 2011 22:12:35 GMT

[quote user="Claire Fisher"]I thought it was the other way round - normal if they've eaten recently but abnormal if fasted for 12 hours prior to sampling?[/quote]

We all know cats are susceptible to fatty liver and how vital nutrition support is in this species.

IIRC the reason it's there post prandial is due to the mechanism of absorbing fats (via the lymphatics).

Re: Cat with hyperlipidemia

Claire Fisher — Tue, 16 Aug 2011 14:12:20 GMT

[quote user="Michael Woodhouse"]

It's normal in a fasting animal. If it has cleared now the animal is eating I would stop worrying.

[/quote]

I thought it was the other way round - normal if they've eaten recently but abnormal if fasted for 12 hours prior to sampling?

Re: Cat with hyperlipidemia

Michael Woodhouse — Tue, 16 Aug 2011 00:53:10 GMT

It's normal in a fasting animal. If it has cleared now the animal is eating I would stop worrying.

Re: Cat with hyperlipidemia

Claire Fisher — Mon, 15 Aug 2011 19:46:44 GMT

[quote user="Richard Fox"]

I would try and rule out GIT disease and lymphoma (just a feeling) but I also found this which is a good review:

http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2003&PID=6509&O=Generic

[/quote]

Thanks, will have a read.

Serum now clear, urine sample was unremarkable, UPC was <0.1. Hopefully going to image him tomorrow.

Re: Cat with hyperlipidemia

Richard Fox — Sun, 14 Aug 2011 07:49:25 GMT

I would try and rule out GIT disease and lymphoma (just a feeling) but I also found this which is a good review:

http://www.vin.com/proceedings/Proceedings.plx?CID=WSAVA2003&PID=6509&O=Generic