High white cells

Re: High white cells

Richard Fox — Tue, 21 Jun 2011 08:00:35 GMT

No probs :)

Re: High white cells

Alan Tevendale — Tue, 21 Jun 2011 07:06:04 GMT

Cheers Richard. The history could certainly fit with a intestinal tumour as the vet who initially look at the cat reported thickened guts. The only other complaint the owner had was weight loss and increased appetite. Not much of a history I know but that with the blood results and now certainly with your interpretation of the smear would be fairly conclusive.

Re: High white cells

Richard Fox — Mon, 20 Jun 2011 09:16:00 GMT

Hi Alan

Just had a look at the slides - there is a marked lymphocytosis and eosinophilia - Lymphocytes are obviously delicate as most ruptured but where intact they are large lymphocytes/blasts (at least 2-2.5 x rbc diam) - so were looking at a lymphoblastic leukaemia - this could, given the history be a terminal event due to a high grade lymphoma i.e. intestinal or a primary marrow tumour i.e. primary leukaemia - I expect the eosinophilia is due to the lymphoid cells being T-cell in origin. Some piccies of large lymphocytes and some including the eosinophils. (from someone not formally trained in haematology, sorry).

Arrow=eosinophils (in other piccies a bit banded)

Arrowheads=large lymphocytes

Re: High white cells

Richard Fox — Fri, 17 Jun 2011 15:13:47 GMT

LOL - OK :)

Re: High white cells

Alan Tevendale — Fri, 17 Jun 2011 14:41:48 GMT

That would have been sensible! I'll email the history and blood results over.

Re: High white cells

Richard Fox — Fri, 17 Jun 2011 10:18:33 GMT

No probs - I'm not an expert haematologist (but OK) but i'd be interested in a look

P.S. - could you include any relevant Hx and blood results?

Re: High white cells

Alan Tevendale — Fri, 17 Jun 2011 09:12:28 GMT

Great Richard, thought you might be interested in it. One of our vets got all excited when she found a few Basophils. I'll pop it in the post this afternoon.

Re: High white cells

Richard Fox — Fri, 17 Jun 2011 08:38:42 GMT

Yup Feel free Alan and I can post up a piccy if there is anything interesting? Just send it to me with a quick letter (not on a sub form otherwise it'll get entered in our system? )

Just mark it for interest only.

Re: High white cells

Alan Tevendale — Thu, 16 Jun 2011 22:36:28 GMT

No sorry no facility to take an image at the practice of any appreciable quality. I'll send you the smear if you'd like Richard?

Re: High white cells

Richard Fox — Thu, 16 Jun 2011 08:07:09 GMT

I guess you can't upload a picture of the smear?

Re: High white cells

Alan Tevendale — Thu, 16 Jun 2011 06:29:23 GMT

Client elected to PTS based on how the cat was doing. Unfortunately not enough money to have the slide sent of for pathologist to look at. Leukaemias or lymphomas would definately be at the top of any list I'd agree.

Re: High white cells

Christopher Saul — Wed, 15 Jun 2011 22:27:48 GMT

What were the pathologist's comments on the WBC morphology? You can get some spectacularly high WBCs with leukaemias or grade V lymphomas.....

Re: High white cells

Cailyn Brown — Tue, 14 Jun 2011 07:10:58 GMT

A high white cell count can be caused by infection or a virus. From my knowledge, increased in the number of white blood cell or commonly known as leukocytosis can be caused by infection, inflammation, allergic reaction, malignancy, hereditary disorders, or other miscellaneous causes.

The increased count of components of white blood cells may be caused by following reasons:

1)Increase in Neutrophil – bacterial infection
2)Increase in Lymphocyte – viral infection
3)Increase in Eosinophil – allergic reaction, parasitic infection

Leukocytosis is not a diagnosis, the cause of leukocytosis is the actual diagnosis. So the vet should interpret the cause of it and start the treatment accordingly.

Re: High white cells

Alan Tevendale — Mon, 13 Jun 2011 19:52:01 GMT

just noticed I got my 8 & 3 wrong way round on lymphocytes. 38 isn't quite so dramatic as 83! OP amended now.

Re: High white cells

Utlendigur — Mon, 13 Jun 2011 19:40:31 GMT

I saw an elderly shar pei earleir this year with a neutrophil count of 51 x10 -9/l

Presented with pyrexia, lethargy, anorexia and occasional vomiting. Biochem fairly unremarkable. Ditto xray. No response to symptomatic tx. But over the course of about 3days what looked initially like a rash over the ventral abdomen/inguinal area developed with unbelievable speed into multiple nodules and lumps. FNAs were packed with mast cells. Dog was pts