PLT not available - any similar alternatives?

Re: PLT not available - any similar alternatives?

Claire Fisher — Thu, 05 May 2011 20:30:13 GMT

Are many people using Pardale long term? (It's only licensed for 5 days I think)

Re: PLT not available - any similar alternatives?

Rob Loxley — Thu, 05 May 2011 18:53:29 GMT

[quote user="Mark Hedberg"]Is "manufacturing problems" code for "make us prescribe expensive drugs?"[/quote]

Sadly PLT is already pretty damn expensive, especially now we have 'generic' meloxicam and carprofen...

Re: PLT not available - any similar alternatives?

Louise6732 — Thu, 05 May 2011 17:49:29 GMT

[quote user="Catherine Williams"]So far the tramadol seems to be working for them[/quote]

Sorry should have said, the dog I'm trying to organise is already on tramadol, previous cocktail tramadol + PLT.

[quote user="Martin Atkinson"]

Why don't you just try the prednisolone on its own as it is probably that which is having the major pharmaceutical effect? Or Cartrophen if you haven't already tried that.

[/quote]

I did consider pred alone, there is only 1mg pred per PLT tablet, dog in question weighs approx 30kg and is on 2tabs BID, so pred dose v.low at approx 0.06mg/kg BID. Worth a shot though if Im totally stuck.

I spoke to the client today and we decided to try Pardale (paracetemol+codeine) and stay on tramadol.

Analgesia lecture at BSAVA speakers said pardale good and often overlooked for paracetemol, codeine dose not v.high at all so codeine component probably doesn't have any effect.

Thanks for suggstions, I guess it's 'manufacturing problems' like these that make us re-think our usual cocktails!

Louise

Re: PLT not available - any similar alternatives?

Mark Hedberg — Thu, 05 May 2011 17:28:32 GMT

Is "manufacturing problems" code for "make us prescribe expensive drugs?" i'm looking at the list of drugs on back order and it's a bit annoying…

Re: PLT not available - any similar alternatives?

Laurence Webb — Thu, 05 May 2011 14:46:20 GMT

[quote user="Martin Atkinson"]

Why don't you just try the prednisolone on its own as it is probably that which is having the major pharmaceutical effect?[/quote] What about pred in combination with paracetemol and/or tramadol. If you want to stick closer to the cascade you could use Pardale instead of generic paracetemol and it's got a bit of codine in for an extra kick

Re: PLT not available - any similar alternatives?

Martin Atkinson — Thu, 05 May 2011 14:31:05 GMT

Why don't you just try the prednisolone on its own as it is probably that which is having the major pharmaceutical effect? Or Cartrophen if you haven't already tried that.

Re: PLT not available - any similar alternatives?

Bob Russell — Thu, 05 May 2011 13:38:17 GMT

I have a soft spot for PLT - it seems to work in a significant number of cases that are not doing well on more modern anti-inflammatory drugs. We have had quite good results with NSAI's and tramadol.

If you search the site for osteoarthritis there have been a number of previous threads on the options!

Re: PLT not available - any similar alternatives?

Catherine Williams — Thu, 05 May 2011 13:33:52 GMT

I think we're moving most of our PLT patients on to tramadol and hoping PLT comes back soon. Like you almost all our PLT patients either can't stomach NSAIDs or have become unresponsive to them. So far the tramadol seems to be working for them