Xylometaziline in dogs

Re: Xylometaziline in dogs

James Laidlaw — Thu, 24 Feb 2011 23:28:42 GMT

Case in question is already on steroids - currently 2.5-5 mg SID/EOD usually controls. O adjusts as necessary. Bisolvon has appeared to have helped (I have incidentally found it useful in a number of cats with copious nasal discharge too) and the dog is also on corvental. O has decided to try the pediatric drops carefully, while aware of risks with unlicensed, non-formulary information provided drugs and I will let you know if there is any benefit when they inform me.

Thanks for the advice.

James

Re: Xylometaziline in dogs

Mark Frost — Wed, 23 Feb 2011 12:04:30 GMT

Xylometazoline is available in many over the counter nasal sprays (0.1% adult or 0.05% paediatric), I have never used it on a patient but from a personal point of view it is amazing stuff when you have a cold, within minutes you can breathe completely freely - I use it whenever I am congested. For people it is one spray per nostril MAX three times daily, but it is important to use it sparingly as when withdrawn it will cause a reflex congestion (and can cause changes to nasal mucosa with longer term use) so I use it first thing in the morning and last thing at night to help me get to sleep - only when I'm feeling rubbish, as soon as I feel myself getting better I reduce to just last thing at night and then withdraw completely. Does dry out your nose a little but I can live with that to relieve the blockage!!

Re: Xylometaziline in dogs

Laurence Webb — Mon, 21 Feb 2011 20:59:46 GMT

Due to the relative difference in the size of a dog's nose and a human's I've tended to think topical drops would be ineffective although I've never tried them.

One thing I have tried in 2 dogs with nasal tumours was Propalin (a bit of lateral thinking, but it does cause vasoconstriction). One snorted marginally less than before though I wasn't convinced. The other had significant epistaxis before starting it, which completely resolved for around 4 weeks.

Re: Xylometaziline in dogs

Evelyn Barbour-Hill — Mon, 21 Feb 2011 18:56:36 GMT

It seems to be another alpha-adrenergic stimulator.

Is the client thinking of it as an empirical treatment as a substitute for rhinoscopy? If so, I can't see it helping in the long term or even in the short term, but I guess you could try it and see (sincerely, I would be very pleased to be proved wrong), with caution.

Or is he thinking of it as a sort of pre-med for the rhinoscopy? It wouldn't do any harm to try there I suppose.

Is there excessive discharge? Are there excessively engorged tissues in the nose? If not, what would the drug do?

Re: Xylometaziline in dogs

Evelyn Barbour-Hill — Mon, 21 Feb 2011 18:54:40 GMT

It seems to be another alpha-adrenergic stimulator.

Or is he thinking of it as a sort of pre-med for the rhinoscopy?

Is there excessive discharge? Are there excessively engorged tissues in the nose? If not, what would the drug do?

(By the way, I have never known Bisolvon do any demonstrable good in anything other than horses.)

Be wary of overdosing.

Re: Xylometaziline in dogs

Michael Woodhouse — Mon, 21 Feb 2011 13:41:01 GMT

Have you tried steroids? They can help these cases amazingly well. He's a Westie, he needs them for something.......