PUPD, anorexic 14wk old puppy

Re: PUPD, anorexic 14wk old puppy

Holly Lee — Sat, 12 Feb 2011 13:02:57 GMT

Thanks Chris - definitely make ultrasound and cysto my next line of enquiry.

Thanks for your help

Holly

Re: PUPD, anorexic 14wk old puppy

Christopher Saul — Fri, 11 Feb 2011 23:32:59 GMT

[quote user="Holly Lee"]Would have expected a pyrexia with a pyelonephritis, and some changes on in house urine cytology.[/quote]

Not necessarily. You mention an SpG of 1.005, when you have urine this dilute, the cells can lyse quite quickly so an inactive sediment doesn't completely rule out pyelonephritis, though I admit makes it less likely. As for the pyrexia, this can wax and wane so again you can't completely rule it out.

In general remember common things are common and pyelonephritis is alot more common than, say, diabetes incipidus (another ddx)

Cheers

Chris

Re: PUPD, anorexic 14wk old puppy

Holly Lee — Fri, 11 Feb 2011 22:13:48 GMT

Thanks, yes it is a female pup. The bloods run included electrolytes (all normal), full biochem including calcium, bilirubin etc, and haematology - although no blood smear examined.

Had considered ultrasound but not performed yet in the light of everything else being normal. Would have expected a pyrexia with a pyelonephritis, and some changes on in house urine cytology. Was a free catch sample so culture not performed, again especially in light of no active sediment. Will definitely consider these as next step. Have (rightly or wrongly...) decided to give a little more time for improvement before further tests in light of the bloods being ok and the pup being currently happy in herself.

Will update on how things progress and any further thoughts welcomed.

Re: PUPD, anorexic 14wk old puppy

Christopher Saul — Fri, 11 Feb 2011 21:56:45 GMT

Is the pup a female?

Firstly, exactly what have you run on your profile? I only say because a typical short/pre ga profile wont include calcium or tbil etc.

My first thoughts are with a pyelonephritis. My minimum profile would include full biochem, elecs and haematology ( pref external lab incl smear analysis) but most importantly a full unrinalysis by cystocentesis to include cutlre and sens, prot:creat ratio and cytology - remember you'll need to include a small plain blood tube with a couple of drops of formalin. I'd prob ultrasound the abdomen to collect the urine under ultrasound guidence, and have a look at the kidneys as well.

With regards your thoughts on a bile acid stim; this isn't an expensive test so I would do this if only as a rule out.

Hope this helps

Chris

Re: PUPD, anorexic 14wk old puppy

Bob Russell — Fri, 11 Feb 2011 11:11:56 GMT

Unlikely but worth checking the food. We did a lot of investigation on a polyd/polyU dog a few years ago that went off its food and it turned out to be a faulty batch of food with high salt levels.