Pentoxifylline in Ischemic injury?? Help!

Re: Pentoxifylline in Ischemic injury?? Help!

Alan Tevendale — Mon, 08 Nov 2010 21:06:37 GMT

Good point about the time after injury. One week should be enough to know what's going to live or not.

I'm with you on the whole honey thing. I love it! Although if your trying to promote granulation at any stage I think there are better alternatives.

Never tried alprostadil - might try it. On a wound!!!

Re: Pentoxifylline in Ischemic injury?? Help!

Martin Jones — Mon, 08 Nov 2010 20:55:40 GMT

After a week, what's alive is alive and what's dead is dead. It'll be a longer term question of keeping infection at bay to find out what will be viable. I have tried a number of things on these to improve local blood flow (including alprostadil, in a human prep for male impotence - try getting that one on prescription from your local chemist - as a poor man's alternative to iloprost), but it's hard to be objective about what works and what doesn't. Age is always a factor, and very young animals will have tremendous repair potential - I once had a cat called Dougie (after Douglas Bader), which I 'received' at six weeks old after it had got its front feet stuck in a piece of farm machinery and almost lost both limbs. Supportive treatment only, and in the end we didn't even need to do grafts. Be prepared to be pleasnatly surprised.

I also really, really like the honey dressings on these - but that's a whole other incitement to riot for some people.

Re: Pentoxifylline in Ischemic injury?? Help!

Alan Tevendale — Mon, 08 Nov 2010 19:09:05 GMT

[quote user="Mark Holmes"]

On a personal note can I suggest immac

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Never tried it myself

Re: Pentoxifylline in Ischemic injury?? Help!

Alan Tevendale — Mon, 08 Nov 2010 19:07:20 GMT

I'd agree that there might not be much that you can do to change the degree of sloughing. Definately agree with wet to dry dressings and copious flushing - hartmans is what I normally use. I've seen a couple of these ending up going down to bone and in most cases look a hell of a lot worse before getting better. Personally I don't like hibi as a wound flush. You should post some photos on here - would really help everyone give some good advice.

The last one I had was a dressing that a client had put on a springer's neck - result swollen head and necrotic wound on neck overlying trachea. Took around 8 weeks to heal properly but fine in the end.

Make sure the client is aware of the committment that they will be needing to put into this. Might even be a case for free skin graft.

Please keep us updated on this one

Re: Pentoxifylline in Ischemic injury?? Help!

Mark Holmes — Mon, 08 Nov 2010 17:43:09 GMT

I would be using wet to dry dressing and flushing copiously on a daily basis to aid in debridement. We have found granulofex useful bet I doubt the area as very good for it. Not convinced anything you do at this stage will change the degree of eventual slough though.

On a personal note can I suggest immac