Periorbital alopecia

Re: Periorbital alopecia

Rob Loxley — Sat, 24 Oct 2009 21:50:51 GMT

diet trial?

Re: Periorbital alopecia

Martin Jones — Mon, 19 Oct 2009 22:32:58 GMT

Biopsies and consider zinc. Any steroid therapies relating to the colitis? I'd look at two aspects (if so): Addisons - certainly seen in a few labs and inheritable; also possibility of calcinosis cutis - in case you might think it far fetched, I had a case this year with very similar presentation (skin problems. Steroids. Skin problems persist. More steroids. You get the picture).

Also, how may skin scrapes before ruling negative. Any ad hoc Stronghold treatments?

Martin

Re: Periorbital alopecia

Andrew Kent — Mon, 19 Oct 2009 20:19:50 GMT

A full skin work up including biopsies sounds like a good plan in this case, would particularly consider autoimmune disease, zinc-responsive dermatosis (check diet) and Leishmania (has occurred without history of travel).

Andy

Re: Periorbital alopecia

Hannah Wynne Richards — Mon, 19 Oct 2009 17:18:44 GMT

My guess, not having seen the case would be lupus

Wynne

Re: Periorbital alopecia

Clive Ansell — Mon, 19 Oct 2009 17:05:32 GMT

If it were me, and the owner wants a diagnosis, I think I would start from scratch and carry out a full dermatology workup, including several skin scapes, full blood work inc thyroid, allergy testing and skin biopsies including grossly normal and affected skin. Maybe systemic autoimmune diseases such as Phemphigus and Lupus should be considered too; I know it is possible to run bloods for ANA, but I am not sure if one can test for Phemphigus autoantibodies?

what previous treatments have been given, and with what success?