https://www.vetsurgeon.org/f/clinical-questions/31241/localised-lymphedema Hello everyone, This is my own dog: 10-year-old female neutered Dutch Shepherd Diagnosed with multicentric lymphoma stage IV/V Currently on prednisolone and lomustine She has developed localized lymphedema (or possibly subcutaneousen-USTelligent Community 10https://www.vetsurgeon.org/thread/247726?ContentTypeID=1Sat, 20 Sep 2025 15:45:41 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:755f79c6-0598-42f7-a8b2-83d330fde623Yantha Smyth<p>I am sorry this is happening, and with your own dog too.&nbsp;<br />I am not sure I can offer anything useful to do, but would be concerned this is due to obstruction of the lymphatics and/or draining nodes such as medial iliacs and will be refractory.&nbsp;<br /><br /></p><div style="clear:both;"></div>