What are people's experiences with ACDS?

RE: What are people's experiences with ACDS?

Sarah Keir — Sun, 10 Sep 2023 17:29:23 GMT

The problem with looking for gall bladder wall oedema as a marker of anaphylaxis, is that other things can cause it and these are also commonly found ACDS (if you go looking). The other common cause of ACDS are viruses, of which we still know very little about (and I'm not meaning parvovirus).

RE: What are people's experiences with ACDS?

David Mills — Sat, 09 Sep 2023 11:29:29 GMT

[quote userid="8663" url="~/f/clinical-questions/30761/what-are-people-s-experiences-with-acds/242373#242373"]Can you share the abstract here?[/quote]

https://www.bsavalibrary.com/content/chapter/10.22233/9781913859152.Ch182

Think it's open access but can post the text if not.

RE: What are people's experiences with ACDS?

Alasdair Hotston Moore — Sat, 09 Sep 2023 04:22:28 GMT

[quote userid="8991" url="~/f/clinical-questions/30761/what-are-people-s-experiences-with-acds/242337#242337"]BSAVA abstracts[/quote]

Can you share the abstract here?

RE: What are people's experiences with ACDS?

David Mills — Thu, 07 Sep 2023 09:29:10 GMT

We produced a study this year at BSAVA abstracts that showed increase survival in parvo dogs receiving dexamethasone during their stay - something like 80% survival in that group versus 50% in historical controls. If covid has showed us anything it is the dogma that you can't give corticosteroids to animals with viral diseases is not correct.

For all cases of haemorrhagic diarrhoea they get c/st, and very rarely abx. There is evidence out there that abx make no difference to recovery times, and may prolong diarrhoea due to changes in the microbiome.

RE: What are people's experiences with ACDS?

Alistair Graham-Evans — Wed, 06 Sep 2023 22:36:56 GMT

Thanks Glen

Will start doing AFast on all these dogs on admission

It wine interesting to see what proportion have gall bladder wall oedema.

RE: What are people's experiences with ACDS?

ALASDAIR MATHIESON — Wed, 06 Sep 2023 20:02:26 GMT

Me too. We saw them at Hampden Park a few years ago, and our experiences were great, but I don't see the connection with Vetsurgeon.

RE: What are people's experiences with ACDS?

Glen McIntosh — Wed, 06 Sep 2023 17:29:04 GMT

Some of these cases, at least, could have been episodes of canine anaphylaxis. They typically present with HGE, prolonged clotting times, elevated ALT, haemoconcentration and are often presented in hypovolaemic shock, depending on severity.

If you put a probe on them you will typically find a gall bladder halo sign (gall bladder wall oedema) and often there is haemorrhagic free abdominal free fluid.

Not all AHDS/HGE episodes are canine anaphylaxis, but certainly some are. Not all episodes of canine anaphylaxis have HGE, but they usually have some GI signs.

Here is a link to some info:

https://fastvet.com/wp-content/uploads/2020/05/08-FASTVet-08-FASTVet-SOCHIRAV-AX-GBWE-5-FASTVet-ABVP-Denver-Canine-Anaphylaxis-2019.pdf

RE: What are people's experiences with ACDS?

Arlo Guthrie — Wed, 06 Sep 2023 14:28:43 GMT

[quote userid="6765" url="~/f/clinical-questions/30761/what-are-people-s-experiences-with-acds/242327#242327"]

Sorry

[/quote]

No need to be Alistair Graham-Evans . I'm just trying to be reasonably strict on the question format, because I think the early signs are good.

I think (although you'd be the better judge), that although we have a bit of a way to go in terms of getting more people to chip in, the quality of the discussions is higher and more focussed.

RE: What are people's experiences with ACDS?

Alistair Graham-Evans — Wed, 06 Sep 2023 12:36:27 GMT

Sorry

Was more to stimulate a discussion around a couple of observations - bit of a tangent off a previous post really

RE: ACDS

Michael Woodhouse — Wed, 06 Sep 2023 11:27:39 GMT

[quote userid="2100" url="~/f/clinical-questions/30761/acds/242322#242322"]Mostly, I can edit titles to a question, but I must say I am struggling with this one!![/quote]

"what are people's experiences with ACDS?"

[quote userid="6765" url="~/f/clinical-questions/30761/acds"]1 - When I did more routine case work I discovered the cases resolving quicker if they received a dose of steroid.[/quote]

I give virtually any dog I treat for V&D maropitant and dexamethasone and fine they bounce back much faster than when not.

RE: ACDS

Arlo Guthrie — Wed, 06 Sep 2023 08:37:07 GMT

Alistair Graham-Evans - What is the question here?! All posts have to have a subject line in the form of a question, for lots of reasons, but mainly because it focuses the mind. Mostly, I can edit titles to a question, but I must say I am struggling with this one!!

RE: ACDS

Richard Carter — Wed, 06 Sep 2023 08:35:58 GMT

But the gut is a shock organ in the dog and as allergic or anaphylactic reactions probably now relatively common or it is a common pathway reaction of the git to toxin/ trauma, steroid does make sense. I also find much better gi response even in the parvo days to steroid over NSAIDs. The thinking then was to keep the dog breathing and alive another day until things could improve