https://www.vetsurgeon.org/f/clinical-questions/30203/use-of-nsaids-in-pyrexic-gastrointestinal-disorders There is a debate at work for the use of nsaids in GI disease for its anti-pyrectic action. The arguement from a collegue is it is ok to use parentally as a one off dose (often with 1/2 to 1/3 dose reduction ) in cases of lethargic / pyrexic GI casesen-USTelligent Community 10https://www.vetsurgeon.org/thread/236777?ContentTypeID=1Mon, 04 Apr 2022 11:57:09 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:bb74f110-dbbe-411d-a7d9-600118ed3deeAndrew Kent<p>Hi Topaz,</p> <p>Apologies for the delay in answering - I suspect there is limited evidence around this but I can tell you what I do!</p> <p>I share your concerns that the presence of concurrent GI disease could increase our risk of adverse effects of NSAIDs - so if I need something of that nature I would tend to reach for paracetamol in the first instance.</p> <p>I do tend to use NSAIDs in FLUTD as long as not obstructive.</p> <p>Andy</p><div style="clear:both;"></div>