https://www.vetsurgeon.org/f/clinical-questions/30165/pemphigus-folliacous-in-a-13-year-old-english-springer-spaniel Dear Dermatologists and Medics. One of my RVNs dogs has been diagnosed with Pemphigus Folliacous as per clinical signs and HP - sent to a derm pathologist. Steroids have been started. Could I confirm the dose of steroids that should be used and foren-USTelligent Community 10https://www.vetsurgeon.org/thread/235364?ContentTypeID=1Mon, 24 Jan 2022 13:24:56 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:c78d9820-07a9-4559-a493-9420718f6823David Bentley<p>An induction dose of pred varies between 1-3mg/kg every 12 -24 hrs., I generally put them on 1mg/kg bid and if this induces remission, wean them off VERY SLOWLY over weeks/months as some will relapse if taken off treatment too soon. Wean down to lowest alternate day dose to keep in remission. Some cases can be taken off treatment completely eventually. Re Oxytet and Niacinamide. Not found it fantastic on its own for pemphigus but could be used alongside steroids. There have been&nbsp;one or two anecdotal reports of Niacinamide on its own helping with some autoimmune diseases....can&#39;t do any harm.&nbsp; &nbsp;Are you sure there is no remaining neoplasia that could possibly be a trigger?</p><div style="clear:both;"></div>