Ampicillin or Amoxycillin.

RE: Ampicillin or Amoxycillin.

Julian Earl — Thu, 16 Dec 2021 20:00:01 GMT

[quote userid="12930" url="~/001/veterinary-clinical/small-animal/medicine/f/discussions/30110/ampicillin-or-amoxycillin/234414#234414"]ampicillin is not as well absorbed from the gut, he[/quote]

Especially in the presence of food! Ampicillin is absorbed less efficiciently, iv 30% cf to 70+IIRC !

HTH??

RE: Ampicillin or Amoxycillin.

Claire Godfrey — Wed, 15 Dec 2021 18:30:50 GMT

That's great thank you.

Couldn't really see why not and client will be happy!

RE: Ampicillin or Amoxycillin.

Beats — Wed, 15 Dec 2021 10:11:21 GMT

[quote userid="2792" url="~/001/veterinary-clinical/small-animal/medicine/f/discussions/30110/ampicillin-or-amoxycillin"]My question is is there any benefit to using ampicillin over amoxycillin?[/quote]

I can't imagine it would make a difference. From memory, ampicillin is not as well absorbed from the gut, hence amoxicillin being the usual preference when treating bacterial infection in the body orally with an aminopenicillin. I guess if aim is to reduce gut bugs only then there is some logic perhaps to choice of ampicillin over amoxicillin, but I expect it is very marginal and theoretical only.

If it was an old case that I had inherited and the management was stable, then I wouldn't interfere too much, but would happily switch ampicillin to amoxicillin for convenience if needed.