https://www.vetsurgeon.org/f/clinical-questions/30091/adverse-antibiotic-reactions Hi, I was wondering if anyone had seen a possible adverse reaction to amoxy / clav? In humans rarely it can cause a cholestatic hepatitis. I have a 3 year old FN lurcher that has been on amoxy clav for a polypoid cystitis. She also received a brief courseen-USTelligent Community 10https://www.vetsurgeon.org/thread/234241?ContentTypeID=1Mon, 06 Dec 2021 22:38:25 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:a06593cd-a237-4609-959c-6608dd3a630bRoland Bulkyn-Rackowe<p>I&#39;ve had a couple previously. A westie with an amoxy clav reaction, a cat with a ceohalexin reaction (went spectacularly red!) and a Springer that had some hepatopathy post TMPS.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/234237?ContentTypeID=1Mon, 06 Dec 2021 21:52:42 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:bbf22c5c-e8a0-477d-8c12-f5f3e3aa3077Stephen Courtney<p>Not as you describe but I have had 2 cases in 30 years ( so bugger all) of antibiotic related skin eruptions. in each case the antibiotic at fault was amoxy-clav. One of these cases it was pescribed for a skin disease - which got worse. switched to cefalexin - also pretty much a beta lactam - continued to get worse. Owner went to a homeopath who stopped the antibiotics and did their thing, and the cat got miraculously better .... of course it did!</p> <p>The other one was more classical and picked up sooner.</p> <p>Oh and I had one case of IMPA that was likely triggered by a sulpha trimethoprim</p> <p>And that&#39;s it - I consult about 6 hours a day and have done so for the last 25 years - so I doubt very much these things are common&nbsp;</p><div style="clear:both;"></div>