https://www.vetsurgeon.org/f/clinical-questions/29711/mct-from-expert-help-forums[quote user=&quot;Fable&quot;]Would love some thoughts on how to approach this tricky MCT case. The dog is a 12yo JRT. Had a lump present on LF for a while, but it was quite small. However in the last few weeks it has dramatically increased in size, he is lickingen-USTelligent Community 10https://www.vetsurgeon.org/thread/228965?ContentTypeID=1Sun, 07 Mar 2021 12:51:41 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:f3502993-4ba4-42b8-9a3a-4d49d8e7fb9bJulian Earl<p>Is Masivet still available? I found it extremely effective in several cases of Mast Cell tumours. Expensive perhaps but so is amputation with the former having the better outcome surely?&nbsp;</p> <p>HTH...</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/228964?ContentTypeID=1Sat, 06 Mar 2021 17:03:43 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:c3d4d9d8-0d7d-459b-8f40-cbc92109af6fBeats<p>Not an expert.</p> <p>I would give that dog 10mg cetirizine daily and 5mg pred daily and see back after a week. Inflammation usually gone down giving more accurate idea of size of mass.</p> <p>Probably would take off the 2 x toes then and pop out popliteal at same time. If dramatically reduced to almost nothing, then might take just one toe and preserve and use&nbsp;outer skin/pad from that toe (&quot;phalangeal fillet&quot;) to close defect of skin over remaining one, but in a JRT with no mobility issues I would think would do fine taking the 2 x toes. I would personally only amputate whole leg if it recurred, but don&#39;t think amputation straight-off would be unreasonable.</p> <p>I looked at stelfonta for a similar case a few months back and it was more expensive than would be to cut off the toes, so I didn&#39;t consider further.</p><div style="clear:both;"></div>