https://www.vetsurgeon.org/f/clinical-questions/29294/infective-endocarditis-in-association-with-mitral-valve-disease Morning all, I feel slightly self-conscious that I shouldn&#39;t be the one asking all the questions but hey ho.... I&#39;ve recently been party to a discussion about IE in dogs wih pre-existing MVD. The published literature shows a very strong bias towardsen-USTelligent Community 10https://www.vetsurgeon.org/thread/224938?ContentTypeID=1Sun, 16 Aug 2020 14:36:26 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:19d92113-7a45-4716-9285-49b5fc83c608Lindsey Edwards<p>I had a cavalier with preexisting murmur present with acute chf signs and pyometra. Stabilised cardiac signs with meds and treated pyo medically with antibiotics and pg. Neither responded terribly well and eventually got consent for ovariohysterectomy. Since recovery dog has &#39;never been better&#39;, chf signs gone and now stable with small murmur, no longer medicated (owner finances). We only presume IE was contributing to the crisis that presented, no echo or cultures performed&nbsp;</p><div style="clear:both;"></div>