Oral plasma cell tumour

RE: Oral plasma cell tumour

Ex Member — Mon, 14 Sep 2020 12:07:33 GMT

Well done, thanks for the update! Finger crossed!

RE: Oral plasma cell tumour

Rodney Ayl — Mon, 14 Sep 2020 10:53:05 GMT

So far so good! Thanks for the update!

RE: Oral plasma cell tumour

David Mills — Mon, 14 Sep 2020 10:15:25 GMT

Update on this case, 1 month on. No sign of recurrence as yet. Removed grotty sutures today as some suture reaction. Fingers still crossed.

RE: Oral plasma cell tumour

David Mills — Tue, 18 Aug 2020 08:14:55 GMT

Thanks for all the replies, very helpful and pragmatic. Performed a partial caudal maxillectomy yesterday, before and after pics below. Aimed for gross 1cm margins, suspicion of some bone involvement lingual aspect. Will see how things progress from here. Thank you again.

RE: Oral plasma cell tumour

Rodney Ayl — Mon, 17 Aug 2020 16:28:38 GMT

Hi David, first let me say that I agree with Chiara 100% in terms of the best approach to these tumors.
I just wanted to add that over the years I’ve had a number of these oral tumors, that mostly ended up as solitary plasmacytoma‘s, in which case surgical excision which does involve some jaw removal has turned out to be curative.
So with the limited finances I think your plan is a good one and if it turns out to be an incomplete excision then one of the short courses of radiation at Southfield’s can take care of residual disease.
There is always the risk of multifocal disease or being part of a systemic plasma cell proliferation and if so time will tell but since the majority of these are benign, I just wanted to let you know that your plan is still a reasonable choice. I would caution the owner though, that though it has a good chance of cure, you won’t know until it is done.

Hope this helps; kind regards

Rodney

RE: Oral plasma cell tumour

Ex Member — Fri, 14 Aug 2020 15:33:59 GMT

Dear David,

Oral plasmacytomas have low risk of metastasis but local control can be challenging; occasionally malignant or multiple plasmacytomas are described. Skeletal invasion is possible to at least oral radiographs would be helpful to tell you if a maxillectomy is needed.

An alternative would be marginal resection with adjuvant radiotherapy or electrochemotherapy or melphalan therapy or palliative therapy only (again radiotherapy, or electrochemotherapy, or melphalan).

Conservative surgery plus two fortnightly treatments with electrochemotherapy may be the most cost effective here with good long term control unless there is extensive bone invasion. I would run a full haematology and serum biochem just in case there is any abnormality there such as cytopenias or monoclonal gammopathy and yes probably check local lymph nodes but hopefully that will all return negative.

Let us know if you need further help!

Dr Chiara Penzo DVM PhD DIP.Ecvim(Oncology) MRCVS
Oncology Referral Service
Willows Veterinary Centre & Referral Practice, Solihull