Use of nsaids in Addisonian dogs on oral prednisolone.https://www.vetsurgeon.org/f/clinical-questions/29157/use-of-nsaids-in-addisonian-dogs-on-oral-prednisolone Given the glucocorticoid dose should be ‘physiologic’, is there really a strong contraindication to using nsaids? Seen a severely arthritic lab today for his zycortal injection. He is already on paracetamol and tramadol. It got me wondering just howen-USTelligent Community 10RE: Use of nsaids in Addisonian dogs on oral prednisolone.https://www.vetsurgeon.org/thread/223806?ContentTypeID=1Tue, 23 Jun 2020 19:21:46 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:e8de0f3d-c75e-4747-a3b2-31cae2ce979fCeri Gruffudd Jones<p>Thank you very much. We do use gabapentin and amantadine as well where nsaids aren&rsquo;t suitable. Interesting that you feel labs have higher incidence of gastric ulceration.&nbsp;</p><div style="clear:both;"></div>RE: Use of nsaids in Addisonian dogs on oral prednisolone.https://www.vetsurgeon.org/thread/223622?ContentTypeID=1Thu, 18 Jun 2020 10:11:22 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:b17d4322-1a06-4354-8fec-709f2d3fba4bLisa Gardbaum<p>In this situation I would probably opt for gabapentin+/or amantadine (off license) first but if there was no improvement I would cautiously use NSAIDs, maybe opting for a COX2 selective ones rather than meloxicam and monitor closely. I personally see proportionally more labs with NSAID induced gastric ulceration anyway so even though the glucocorticoid dose is physiological which should not add a significantly higher risk to using NSAIDs in most addisonian dogs,&nbsp; I would monitor for GI side effects closely&nbsp;</p><div style="clear:both;"></div>