https://www.vetsurgeon.org/f/clinical-questions/29099/environmental-damage-from-parasite-control-treatment Isoxazoline treatments for parasites in small animals are effective and currently widely used. Is there any concern over long term environmental changes that could result from their widespread use ? In this current covid pandemic the one thing I haveen-USTelligent Community 10https://www.vetsurgeon.org/thread/222596?ContentTypeID=1Thu, 14 May 2020 14:18:47 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:4629289c-f932-47f7-afdc-3308b7fe2fb4David Bentley<p>I&#39;m not sure about oral Isoxazolines as I believe they are excreted unchanged in urine and faeces, but they are probably a safer bet than topicals.&nbsp; There was a recent letter in one of the UK vet journals recently&nbsp;&nbsp;estimating that with Imidocloprid spot -ons there is enough product in a large dog dose of spot on to kill half of the invertebrates/insects in a lake the size of an olympic swimming pool if the dog went for a swim&nbsp; soon after treatment.&nbsp; I suspect topical Izoxazolines&nbsp; would carry a similar risk.</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/222565?ContentTypeID=1Thu, 14 May 2020 09:18:45 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:643a6848-6479-4cbe-92ce-c4a4ac81b6b2Mark Craig<p>I think we need to be much more mindful of the effects our parasiticides are having on the environment. There is evidence that veterinary products are contributing to environmental pollution.</p><div style="clear:both;"></div>