Sodium Bromide in Epileptic Dogs?

Re: Sodium Bromide in Epileptic Dogs?

Cat Henstridge — Mon, 03 Aug 2009 08:47:31 GMT

Hi guys,

Thanks very much for your comments, very helpful! Turns out the dog had settled on the KBr anyway by the time I got back to the owner!

Cat

Re: Sodium Bromide in Epileptic Dogs?

Hanna Bennett — Thu, 23 Jul 2009 22:03:57 GMT

Have had a few dogs vomit on the capsule form of KBr (Epilease) and then swapped them onto the powder which we mix with water for the owner to give orally as a solution. Not one dog has vomited on this formulation, and the owners are more than happy with the fact that it is considerably cheaper! Use the same dose, and have no issues with fit control changing.

Re: Sodium Bromide in Epileptic Dogs?

Niall Taylor — Thu, 23 Jul 2009 21:59:58 GMT

[quote user="Cat Henstridge"]His pb levels are perfect (bang in the middle of the range)[/quote]

Bear in mind that 'bang in the middle' means you've got room to play with regarding the dose rate, some dogs require higher serum levels than others, why not try increasing the phenobarb dose.

What form of KBr are you giving?

Cheers,

Niall

Re: Sodium Bromide in Epileptic Dogs?

Andrew Kent — Thu, 23 Jul 2009 20:24:00 GMT

Hi Cat,

I have never used NaBr myself but I have heard of its use when KBr seems to cause gastric irritation. I understand the dose of NaBr is 15% lower than KBr dose, but it is difficult to monitor whether you are in therapeutic levels as I am not aware of anybody that can accurately measure this.

The other drug I would consider if this is not an option is Levetiracetam (Keppra) which I have seem some good results with.

Andy