https://www.vetsurgeon.org/f/clinical-questions/28413/herpes-virus-infection-in-dogs Have found out a breeder client has a positive herpes titre on more than one dog, including the male used for stud. From what I have been able to find out the vaccine is really about saving litters from fading pup syndrome and nothing to do with helpingen-USTelligent Community 10https://www.vetsurgeon.org/thread/214151?ContentTypeID=1Wed, 31 Jul 2019 21:01:32 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:8a57ccf6-add2-461a-8bd2-0a6d82f53173Dinu Catilina<p>Herpes virus is pretty common and affects around 50% of the breeding stock in a study in Belgium and 85% in Norway.</p> <p>I would ignore the stud dog and vaccinate the females when they&#39;re bred from. In theory the maden females are most likely to be affected but I would vaccinate at any age.&nbsp;</p> <p>The new breeding stock will most likely have herpes anyway! It&#39;s not the end of the world.&nbsp;</p> <p>Edited to add some more info. It&#39;s not very clear how many of the puppies neonatal deaths are directly related to herpes virus. A study in Denmark showed that out of 57 puppies only 22% were positive for herpes and only 1 had patognomonic lesions.&nbsp;</p><div style="clear:both;"></div>