https://www.vetsurgeon.org/f/clinical-questions/28119/sterile-nodular-panniculitis So with the owner&#39;s permission, this is Harry. He&#39;s now 9 yo a little overweight due to steroid use trying to control this condition. When he first developed it a couples of years ago (afai recall), he would spontaneously develop abscesses anywhereen-USTelligent Community 10https://www.vetsurgeon.org/thread/210053?ContentTypeID=1Tue, 09 Apr 2019 20:05:34 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:74335827-9cc8-4bc0-9dc5-2816d150fd43Beats<p>I&#39;ve no answers, just commiserations that I personally hate these cases!</p> <p>Sometimes, i&#39;ve observed poorly defined cases that have cyclical disease with fistulae forming and then resolving (usually in same anatomical location for that patient) with sometimes days, weeks, months or years between episodes. sometimes there is a history of healing with antibiotics, or healing with steroids, or healing with doxycycline/niacinamide or whatever... and very hard to decide on causality or not...</p> <p>If no serious ciclosporin side effects, and can financially manage once daily on ongoin basis, and you think there has likely been good response to this treatment so much as you can tell, then I&#39;d personally prefer to continue this. If there&#39;s some flares in this isolated area, then as long as they self-resolve I&#39;d probably live with that if nto too frequent. Alternatively, I&#39;d check cytology and make sure appears reasonably sterile and no suspicious fungal/(atypical) bacterial culture ideally and use methylpred at maybe 4mg daily for 5 to 10 days if flare occurs at first sign. A decent dose of steroid at first suggestion of flare of steroid responsive disease for a short (even day or two sometimes) time can sometimes nip things in the bud IME.</p><div style="clear:both;"></div>