Mitotane protocol in small dogs

RE: Mitotane protocol in small dogs

Andrea Tarr — Wed, 10 Apr 2019 10:23:40 GMT

The Royal Dick Small Animal Hospital pharmacy is the only veterinary 'compounding pharmacy' in UK that I know of (i.e. not an authorised specials manufacturer). Compounding pharmacy is an American term that is being adopted - here we've called it extemporaneous preparation. (In the UK, pharmacists in general have largely stopped doing this and will usually get specials from a specials manufacturer). The Royal Dick produces a limited range e.g. tylosin capsules, budesonide capsules and external creams) and can prepare bespoke formulations; .https://www.ed.ac.uk/vet/services/pharmacy/compoundingpharmacies

RE: Mitotane protocol in small dogs

Beats — Tue, 09 Apr 2019 20:16:20 GMT

Probably redundant on Andrea's post, but if wishing awkward formulation compounded etc, i tend to start here:

https://www.ed.ac.uk/vet/services/pharmacy/compoundingpharmacies

RE: Mitotane protocol in small dogs

Andrea Tarr — Tue, 09 Apr 2019 10:03:50 GMT

The Specials Laboratory list mitotane capsules among the formulations they prepare.

http://www.specialslab.co.uk/

RE: Mitotane protocol in small dogs

Ian Ramsey — Wed, 06 Mar 2019 08:34:57 GMT

Good question!

The dose is 50mg/kg but the tablets are 500mg and in theory should not be divided.

Two options

a) Divide them (use a pill splitter, gloves and if you have one a fume hood).

b) Get a compounding pharmacy to split them (suspect very expensive)

c) Give dose every other day during induction.

Personally I have always gone with option a) but I split the tablets using precautions described and give the tablets to the owner. However I think this decision depends on a lot of other factors such as availability of compounding pharmacies who are willing to do this for a realistic price.

Hope this helps

Ian