RE: Poisons slowly disappearing

Linda Filshie — Fri, 01 Feb 2019 07:11:53 GMT

Thanks Jane, that's really helpful.

RE: Poisons slowly disappearing

jd2008 — Fri, 01 Feb 2019 06:06:00 GMT

Hi Linda, it's a fairly common toxicosis here in Australia (unfortunately these baits are marketed as 'pet friendly') but I can't recall seeing it in the UK so not ignorant at all.

This case series was written by two former colleagues: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1751-0813.2009.00451.x I might still have the full paper hidden somewhere on my hard drive but in summary it causes profound GI ulceration and GI distress with the potential for nasty stricture formation if not treated early enough. Another issue with delayed treatment is oxidative organ damage.

Presentation can be misleading as dogs will commonly show moderate GI distress within the first few hours following which appears to resolve spontaneously within the first 24hrs so many go untreated initially.

Treatment is very effective if given early enough: chelation with desferrioxamine CRI until serum iron levels returned to normal. You can also judge the efficacy of treatment by monitoring urine colour. Local human laboratories in Australia will run serum iron analysis with a very quick turnaround. Adjunct treatment is aimed at GI protection (proton pump inhibitors +/- H2 antagonists) and supportive care (analgesia, iv fluids). Many of the intoxications I dealt with required several days of chelation which ended up being pretty costly.

Jane

RE: Poisons slowly disappearing

Linda Filshie — Thu, 31 Jan 2019 21:41:55 GMT

Excuse my ignorance but what effect does ferric edta have on mammals?

RE: Poisons slowly disappearing

jd2008 — Thu, 31 Jan 2019 08:49:43 GMT

Sadly metaldehyde baits will probably simply be swapped for iron EDTA ones instead