Addisons

RE: Addisons

michelle white — Tue, 22 Jan 2019 13:14:07 GMT

Press were started after cortisol readings

RE: Addisons

Xyresic — Mon, 21 Jan 2019 21:20:33 GMT

Ah, all bets are off if the dog was on prednisolone I’m afraid as that will have affected the basal cortisol. I guess if clinical signs abate post-op you’ll have your diagnosis (not Addisons!) if not retest once been off preds for a while. Good luck!

RE: Addisons

michelle white — Mon, 21 Jan 2019 20:37:34 GMT

Was being treated as atypical with Prednisolone, some signs improved but then vomiting significantly worsened, xrays demonstrated large piece of bone in stomach (chicken thigh) which was removed via gastrotomy, question is was bone there before or just eaten the night before as polyphagic on steroids and owner did see dog get hold of something and took bone out of mouth! Lots of clear fluid in abdomen which has been sent for analysis!

RE: Addisons

Xyresic — Mon, 21 Jan 2019 20:15:01 GMT

Would strongly suspect atypical addisons based on basal cortisol that low. If the dog is ‘stressed’ - which I guess it will be if you‘re suspecting Addisons, then it should have a basal cortisol higher than that. But that’s probably not good enough in itself to make a certain diagnosis...

RE: Addisons

michelle white — Mon, 21 Jan 2019 19:49:58 GMT

Basal cortisol readings of less than 15 on first test and 19 on 2nd one. Normal electrolytes. Dechra no date on availability!

RE: Addisons

Anthony Dennison — Mon, 21 Jan 2019 15:56:22 GMT

[quote user="Xyresic"]Have you done a basal cortisol? If greater than 55mmol/l then unlikely to be Addison’s - although you still really need to do an ACTH stim to confirm if less than 55mmol/l.[/quote]

In the past I have just gone for basal cortisol to try and keep costs down for owners - no point as often I still had to do an ACTH stim test afterwards. I would go straight for this once some Synacthen or Tetracosactide has been sourced.

[quote user="Rob Davis"]Try speaking to Dechra, they are generally very helpful.[/quote]

I agree - often they can send you some direct through your wholesaler. If not, they will help you find some.

RE: Addisons

Rob Davis — Mon, 21 Jan 2019 15:50:31 GMT

Try speaking to Dechra, they are generally very helpful.

RE: Addisons

Xyresic — Mon, 21 Jan 2019 15:50:12 GMT

Have you done a basal cortisol? If greater than 55nmol/l then unlikely to be Addison’s - although you still really need to do an ACTH stim to confirm if less than 55nmol/l. Remember too that approx 10% of Addisonian dogs will be atypical ie no significant change in electrolytes. Definitely always worth ruling out early on - and definitely before you start steroids!