Slowly progressive cerebellar signs in an adult farm dog - Neospora?

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Emily Rainbow — Sun, 20 Jan 2019 21:24:56 GMT

I’ve had a couple of cases sent for mri that returned with diffuse/symmetrical cerebellar changes that were put down to those deficiencies. Think it was thought to be more of a metabolic/absorption cause rather than a dietary deficiency.

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Iain Richards — Sun, 20 Jan 2019 20:20:05 GMT

[quote user="Jill Butterworth"]Hydatid cyst in the cerebellum? [/quote]

No. Dog is the definitive host.

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Jill Butterworth — Sun, 20 Jan 2019 19:58:27 GMT

Hydatid cyst in the cerebellum?

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Rach — Sun, 20 Jan 2019 15:37:42 GMT

Thanks all. Some sort of atrophy had crossed my mind too, as had a meningioma. I think steroids can slow progression a bit in the latter, but I would be a bit hesitant with neospora and toxo still on the differential list. Currently it is receiving benign neglect.

No cranial nerve signs (that I indentified at least), but I think that fits with a cerebellar localisation (i.e. there aren’t any cranial nerves that originate in the cerebellum).

Emily, is the B1/B12 supplementation suggestion related to your comment about abrioteophies or in case it has a dietary deficiency?

Thanks again,

Rach

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Emily Rainbow — Fri, 18 Jan 2019 10:34:16 GMT

Also consider something like cerebellar abiotrophy or similar.

Supplement with b1 and b12 and see?

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Iain Richards — Wed, 16 Jan 2019 12:35:17 GMT

Sorry, late to this one.

Anything more than cerebellar signs that might help localise the lesion such as cranial nerve function? As it's progressive over that length of time it's reasonable to conclude this is either an atrophy eg amyloid deposition, or destruction by space occupying lesion - tumour or abscess. It's unlikely to be an active infectious process so your clindamycin is not that useful.

Steroids then PTS if QoL poor. (Happy for the above to be dismissed as speculative bollcks by a neuro type!)

RE: Slowly progressive cerebellar signs in an adult farm dog - Neospora?

Roland Bulkyn-Rackowe — Wed, 16 Jan 2019 11:35:37 GMT

Not in a Labrador but I have seen progressive cerebellar ataxia in an adult (3-4 year old) Parson Terrier, and it is considered to be an inherited degenerative condition. I also saw a much younger Labrador affected (signs started at 10 weeks). This was also considered to be inherited and the dog was put to sleep at 5 months old.