https://www.vetsurgeon.org/f/clinical-questions/27338/latest-suggestions-for-fiv Hi, I&#39;m seeing a cat at the moment with ongoing pyrexia, mild lethargy, &amp; some mild neuro signs - mainly mild ataxia &amp; odd headshaking/facial twitching, plus now mild D+. Investigations so far show low WBCs with marked neutropenia, FIV +ve on Westernen-USTelligent Community 10https://www.vetsurgeon.org/thread/202098?ContentTypeID=1Fri, 31 Aug 2018 20:22:11 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:6b44e71c-aa78-45cd-8543-501e3bd3a767David Mills<p>I don&#39;t think there&#39;s anything new under the sun, it&#39;s a while since I&#39;ve done any shelter stuff. Fiv normally doesn&#39;t have that much of an immunomodulatory effect except when severe or the cat is already debilitated.&nbsp;</p> <p>The bigger worry is the toxo. Cats that fail to favourably and significantly respond in the first few days have a worse prognosis.</p> <p>Corticosteroids are indicated where there are neuro signs, a lot of the signs may be attributable to inflammatory response.&nbsp;</p><div style="clear:both;"></div>https://www.vetsurgeon.org/thread/202065?ContentTypeID=1Fri, 31 Aug 2018 13:47:33 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:47403105-251c-434e-8237-020a90a43c81Martin Atkinson<p>You can try recombinant feline interferon it may work as an immunomodulator as well as by its anti-viral action.&nbsp;</p> <p>Recommended dose is 1 mega unit/kg every other day for 5 doses. If it seems to help repeat in 14 days if it doesn&#39;t it is likely a non-responder. Periodic sets of further 5 injections may be needed according to well being/clinical status</p><div style="clear:both;"></div>