Leishmaniasis in a nine month british born dog

RE: Leishmaniasis in a nine month british born dog

Niall Taylor — Mon, 20 Aug 2018 14:28:38 GMT

OK, thanks Andy - hope you're well :-)

Niall

RE: Leishmaniasis in a nine month british born dog

Andrew Kent — Mon, 20 Aug 2018 13:41:21 GMT

[quote user="Niall Taylor"]

[quote user="Andrew Kent"]The main other reports of leishmania in the UK have been in dogs who have lived with travelled dogs.[/quote]

Andrew Kent - do you have a reference for this by any chance? I have a similar case looming at the moment.

Cheers,

Niall

[/quote]

Hi Niall,

This was reported as an abstract at the Small Animal Medicine Society (SAMsoc) pre-congress day in April by one of the medicine residents from RVC but I don't think it is yet published. From discussions around that I understand that another centre has also seen a similar case and there is likely a case report in publication...

Andy

RE: Leishmaniasis in a nine month british born dog

Niall Taylor — Mon, 20 Aug 2018 12:20:14 GMT

[quote user="Andrew Kent"]The main other reports of leishmania in the UK have been in dogs who have lived with travelled dogs.[/quote]

Andrew Kent - do you have a reference for this by any chance? I have a similar case looming at the moment.

Cheers,

Niall

RE: Leishmaniasis in a nine month british born dog

Michael Woodhouse — Wed, 08 Aug 2018 16:49:58 GMT

I think the dog actually having leishmania would be more odd........

RE: Leishmaniasis in a nine month british born dog

Andrew Kent — Wed, 08 Aug 2018 15:06:45 GMT

Thanks for the update. this would be a good one to get reviewed by another pathologist I think as all a bit odd!

RE: Leishmaniasis in a nine month british born dog

janine redman — Wed, 08 Aug 2018 11:48:23 GMT

Hi the PCR on histo sample came back negatuive and the sample has gone back to the clinical assessment group at idexx and they have requested serology. All a bit costly to the poor owner and a continuing conundrum at the moment

RE: Leishmaniasis in a nine month british born dog

Andrew Kent — Wed, 08 Aug 2018 08:16:08 GMT

Did you have any update on the histo Janine?

Andy

RE: Leishmaniasis in a nine month british born dog

janine redman — Mon, 30 Jul 2018 15:47:22 GMT

Awaiting feedback from lab , will check tomorrow.

RE: Leishmaniasis in a nine month british born dog

Laura Marshall — Mon, 30 Jul 2018 12:17:16 GMT

Do you have access to your vet connect IDEXX account? They sometimes put images of cytology on the file. Would be interesting to see.

RE: Leishmaniasis in a nine month british born dog

Andrea Tarr — Mon, 30 Jul 2018 11:52:02 GMT

Naucke TK, Lorentz S. First report of venereal and vertical transmission of canine leishmaniosis from naturally infected dogs in Germany. Parasit Vectors 2012; 5: 67.

RE: Leishmaniasis in a nine month british born dog

janine redman — Sat, 28 Jul 2018 21:24:25 GMT

Histopath by idexx labs . Not had a chance to discuss it yet. Lesion was like a flattened verrucoid lesion. Not erythematous , nor pruritic initially. Initial punch biopsy we took for diagnosis indicated MCT and showed some of the leishmania bodies.

Neither dog nor owner nor the in contact dogs have travelled abroad. Dog bred in Winchester and rarely , if ever, has left the area of the New Forest. Plenty of mosquitoes and other flying , biting insects around in the New Forest though. They live inside the New Forest National Park boundary.

RE: Leishmaniasis in a nine month british born dog

David Mills — Sat, 28 Jul 2018 21:17:46 GMT

[quote user="janine redman"]

Cytologist has seen multiple inclusion bodies , running pcr tests now. He or she is pretty confident of the diagnosis

[/quote]

With respect, you do not yet have a diagnosis so I would be cautious about "premature closure" on this.

It sounds very unlikely looking at the history you have provided.

RE: Leishmaniasis in a nine month british born dog

Andrew Kent — Sat, 28 Jul 2018 14:46:14 GMT

Interesting.... where do you send your histopath to? and do you know if this has been reviewed by any other pathologists?

It would be unusual (although clearly not impossible) to see a mast cell tumour in such a young dog and also unusual to see leishmania in a non-travelled dog. The combination therefore seems even more unusual!

Have any of the owners other dogs travelled? The main other reports of leishmania in the UK have been in dogs who have lived with travelled dogs.

The PCR is sensible, as would be leishmania serology, but I might also ask for the pathology to be reviewed by somebody else.

Andy

RE: Leishmaniasis in a nine month british born dog

Dinu Catilina — Sat, 28 Jul 2018 08:10:44 GMT

[quote user="Francisco Gomez"]Do we know how the disease transmission happen in the absence of the vector?[/quote]

There was a case report in Germany with confirmed transmission after a dog fight. There are also strong suspicions that it can be transmitted through semen which is probably not a concern in this particular case.

RE: Leishmaniasis in a nine month british born dog

Francisco Gomez — Sat, 28 Jul 2018 07:46:52 GMT

When I lived in Spain, leishmania was a routine diagnosis and many clients lived happily with dogs diagnosed with the disease.

That is not to say the risk to humans is non existent but I suspect is very low.

Do we know how the disease transmission happen in the absence of the vector?

RE: Leishmaniasis in a nine month british born dog

janine redman — Sat, 28 Jul 2018 01:09:26 GMT

Cytologist has seen multiple inclusion bodies , running pcr tests now. He or she is pretty confident of the diagnosis

RE: Leishmaniasis in a nine month british born dog

Michael Woodhouse — Sat, 28 Jul 2018 00:57:18 GMT

My first question with a diagnosis such as that (given the history) is could this be a misdiagnosis/false positive?