Long term use of Pardale-V (paracetamol+codeine)

RE: Long term use of Pardale-V (paracetamol+codeine)

Rob Davis — Sat, 19 May 2018 08:44:47 GMT

Yes, frequently, often in conjunction with NSAID and/or tramadol. I usually go with the BSAVA formulary dose of 10mg/kg to start, but am happy to increase if not effective at this dose. Never knowingly seen any problems.

RE: Long term use of Pardale-V (paracetamol+codeine)

Beats — Thu, 17 May 2018 20:29:06 GMT

If it's GI signs related to the actual drug going through the Gi system (i.e. includes acute diarrhoea or vomiting on taking rather than development of stomach/duodenal ulcer), then I've found Trocoxil rather useful. Sounds crazy to give a long-acting NSAID in a dog that hasn't tolerated other NSAIDs, but I think a lot of these are not tolerating the NSAID hitting their GI tract every day rather than the systemic adverse effects of COX-inhibition.

RE: Long term use of Pardale-V (paracetamol+codeine)

Michael Woodhouse — Thu, 17 May 2018 20:18:23 GMT

[quote user="Adebowale Ajao DVM, PGCertSAM, MRCVS"]Has anyone used Pardale-V for the long term management of osteoarthritis.[/quote]

Yes. Lots. At full label dose either bid or tid for many years with zero problems. Usually in conjunction with NSAIDs. Off licence but fine and very effective.

RE: Long term use of Pardale-V (paracetamol+codeine)

Clive Ansell — Thu, 17 May 2018 16:32:21 GMT

Yes, occasionally.

I have an ongoing case in one of my regular practices, an old Labrador with spondylosis where nsaid's and Tramadol don't suit him, and he's doing reasonably well on a combination of pred and pardale-v at an sid rather tid dose.

It is only licenced for acute traumatic pain, or post operatively for a maximum of 5 days of course, so off label with a signed disclaimer.