https://www.vetsurgeon.org/f/clinical-questions/26631/t-cell-lymphoma one of our receptionists has a 7 year old hovawart which has recently been diagnosed with stage 111b T cell lymphoma . She has started on the CHOP protocol but asked if there were any other possibilities for a longer term prognosis ? en-USTelligent Community 10https://www.vetsurgeon.org/thread/191967?ContentTypeID=1Mon, 29 Jan 2018 18:30:10 GMT146601cc-3922-4be7-9974-7e1d4e45a66b:bc2bcb6a-2788-4da8-a76b-49cca4b05a4bGerry Polton<p>Hi Janine</p> <p>We typically treat these with a lomustine-based protocol. My patients usually receive lomustine and L-asparaginase. Colleagues I know will often use the same plus vincristine. Choices are influenced by the clinical presentation including anatomic distribution of lesions, presence or absence of bone marrow infiltration, specific morphological subtype of the lymphoma if that can be defined. It would be worth considering referral to an oncologist in this case. Failing that, consider lomustine (70mg/sqm q 28d) and prednisolone (1mg/kg SID) as a rescue therapy if CHOP has not achieved complete remission within six weeks or if remission is achieved but relapse develops.</p> <p>Yours</p> <p>Gerry</p><div style="clear:both;"></div>